Nature Communications
Articles in this Issue
In situ reprogramming of CAR-alveolar macrophages via liposomal nanomedicine for lung cancer immunotherapy
Characterization of membrane structures regulating primary ciliogenesis by quantitative isotropic ultrastructure imaging
Abstract The trafficking, docking, and fusion of membrane vesicles at the mother centriole (MC) are important for primary cilium construction. Here, we determined the three-dimension...
Intrinsic DNA codes govern distinct modes of nucleosome-transcription factor interactions
Spatial architecture of autism pathogenesis reveals mosaic structural disarray during early development
Operando identification of anion effect on lithium nucleation and growth via in situ transmission electron microscopy
Annealing of skyrmion lattice in van der Waals magnet via field modulation
Regional sex differences in human cortical anatomy vary in their morphometric bases and overlap with sex chromosomal and gonadal influences
Abstract Humans show reproducible sex differences in regional cortical volume (CV), but it remains unclear how these relate to the two biologically dissociable d...
Single-atom substitution redirects KatG reactivity from cofactor biogenesis to stereoselective sulfoxidation
Abstract Protein-derived cofactors rely on precisely positioned heteroatoms to direct redox chemistry, yet isolating their individual contributions remains chall...
Spatial cellular order underlies locally-confined mechanisms of immune resistance in oropharyngeal cancer
Abstract Oropharyngeal squamous cell carcinomas (OPSCCs) frequently result from oncogenic human papilloma virus (HPV) infections (HPV-OPSCC). The mechanisms underlying effective immu...
Molecular pharmacodynamics of amoxicillin-clavulanic acid for urinary tract infections caused by Escherichia coli
Abstract Amoxicillin-clavulanic acid (AMX-CLV) is a widely used oral β-lactam/β-lactamase inhibitor combination against Escherichia coli...
Electrochemical artificial humification for sustainable waste biomass valorization and soil remediation
Enhanced fragmentation of water dications upon high Rydberg states
Synthesis of functionalized hydrosilanes via titanium-catalyzed hydroboration and hydrogenation of C(sp3)–Si bonds in silacyclobutanes
The embryo game uncovers hidden cell behaviours
YBX1 Confers immunosuppressive bone metastatic traits in non-small cell lung cancer
Abstract The spread of lung cancer to bone is a devastating complication often linked to resistance against immunotherapy, but the reasons for this connection are poorly understood....
Crop fields complement biodiversity in permanent grasslands across European landscapes
Abstract Temperate agricultural landscapes are experiencing unprecedented biodiversity declines. Landscape simplification is commonly identified as a driver of species loss across ta...
Robust bulk silicon carbide polymorphs sintered from collapsed hollow mesoporous structure
Deciphering small sequence differences in T cell receptor-antigen pairing
Clonal evolution and mutational trajectories of metastatic colorectal cancer shaped by anticancer therapies
Covalently bonded polymer-metal-organic framework semiconductive membranes for flexible X-ray detection
Mid-infrared snapshot spectral imaging via nonlinear radial dispersion
The PLK4 inhibitor RP-1664 demonstrates potent efficacy in neuroblastoma preclinical models through a dual mechanism of sensitivity
Abstract It was recently shown that inhibition of polo-like kinase 4 (PLK4) induces synthetic lethality in cancers with chromosome 17q-encoded...
Generative flow model on distance geometry for predicting transition states of chemical reactions
A probabilistic forecasting framework for neighbourhood-level disaggregation of electric vehicle adoption scenarios
Abstract The rapid growth of electric vehicle (EV) adoption presents significant challenges for electricity networks, particularly at the low-voltage level, where clustered neighbour...
Trial-by-trial fMRI-neurofeedback dissociates fusiform and occipital contributions to face detection and recognition
Abstract Self-regulation of specific brain regions can be achieved using neurofeedback with real-time functional magnetic resonance imaging (rt-fMRI). We leverag...