Nature Communications
Articles in this Issue
Biomimetic metal-drug coordination nanoplatform to counteract drug resistance in Pseudomonas aeruginosa via energy disruption
Functional distinctions between orbitofrontal cortex and anterior cingulate cortex subregions in decision-making and autonomic regulation
Brain-derived neurotrophic factor and the derived dodecapeptide function as Toll-like receptor 4 antagonists in acute lung injury
Advancing neuroengineering with Neuromorphic Twins
Observation of a backward sliding motion for rollers on surfaces in viscoelastic fluid
Abstract When wheels roll on the ground, they move forward via the contact friction. This propulsion mechanism is also frequently used to create artificial microswimmers in viscous l...
FOXJ1 mediates taxane resistance through regulation of microtubule dynamics
Abstract Docetaxel is the first-line chemotherapy for metastatic prostate cancer (PC), but clinically meaningful mechanisms of resistance remain to be establishe...
Spatiotemporal interplay between epithelial and mesenchymal cells drives human dentinogenesis
ATRX loss couples genome instability at a G-rich repeat to dysregulation of human alpha-globin expression
Abstract Germline mutations in the chromatin remodelling protein ATRX cause a severe developmental disorder associated with α-thalassemia. In addition,...
CycloPepper: a machine learning platform for predicting cyclization outcomes and optimizing synthesis of therapeutic cyclopeptides
Abstract Cyclic peptides exhibit remarkable stability, membrane permeability, and binding affinity, positioning them as promising therapeutics. However, their synthesis, particularly...
Surface hydroxyl-induced Pt0 clusters on TiO2 for synergistic water gas shift catalysis
GLP-1 activates KATP channels in coronary pericytes as the effector of brain-gut-heart signalling mediating cardioprotection
Abstract Failure to reperfuse the coronary microvasculature (“no-reflow”) affects up to 50% of patients after unblocking a coronary artery that was causing ischa...
Do-it-yourself protein arrays as high-throughput immunoassays enabled by confined droplets on patterned plasmonic chips
Physical limits of sea-level rise adaptation in global river deltas
Abstract Sea-level rise threatens deltas worldwide, requiring adaptation to flood risks. Delta adaptation is typically presented as a choice between five strategies: advance, protect...
Activity in human dorsal raphe nucleus signals changes in behavioural policy
Abstract The dorsal raphe nucleus (DRN) is an important source of serotonin to the human forebrain, however there is little consensus about its behavioural function. We build on rece...
Near real-time full-wave inverse design of electromagnetic devices
Enhanced superconductivity and mixed-dimensional behaviour in infinite-layer samarium nickelate thin films
Portable hip exoskeleton improves walking economy for stroke survivors
Deficiency of lysosomal TMEM175 in myeloid macrophages exerts anti-tumor immunity via inflammasome and cross-presentation pathway
Co-transcriptional folding orchestrates sequential multi-effector sensing by a glycine tandem riboswitch
Single-crystal 2D covalent organic frameworks for high-capacity methane storage
Abstract 2D covalent organic frameworks (COFs) usually possess a polycrystalline nature as well as lower porosity and surface area than 3D counterparts, restrain...
Dual reaction strategy for in-situ conductivity enhancement to enable high-performing aqueous zinc-based micro-batteries
Large-array sub-millimeter precision coherent flash three-dimensional imaging
Structure and mechanism of the HECT ligase HECTD3
Abstract HECT E3 ligases regulate many cellular processes, yet how they recognise their substrates and synthesise specific types of poly-ubiquitin chains is still incompletely unders...
Evolution of object identity information in sensorimotor cortex throughout grasp
Extreme optical nonlinearities unveiled by ultrafast laser filamentation in semiconductors
Abstract Sky-high optical nonlinearities make semiconductors ideal platforms for multifunctional photonic devices. The fabrication of such complex devices could greatly benefit from...