Nature Communications
Articles in this Issue
Hygroscopicity-driven spontaneous sustainable direct lithium extraction
Endothelial C-type natriuretic peptide/guanylyl cyclase-B signaling prevents pulmonary arterial hypertension
Abstract C-type natriuretic peptide (CNP) is released from endothelial cells and acts as an autocrine/paracrine mediator, regulating systemic blood pressure and...
Low thermal inertia of carbonaceous asteroid Bennu driven by cracks observed in returned samples
An intralayer microcircuit in the temporal association cortex underlies sensory-induced escape in mice
Abstract A central goal in neuroscience is to clarify how neural circuits translate sensory input into adaptive behaviours. Although unisensory evoked escape circuits in mice are wel...
Biosynthesis of pyomelanin from methanol with engineered Komagataella phaffii and its characterizations
Bidirectional regulation of social memory by two distinct types of GABAergic neurons in the lateral septum
Multimodal imaging reveals a lysosomal drug reservoir that drives heterogeneous distribution of PARP inhibitors
Abstract For all drugs, effective target engagement requires sufficient intracellular concentrations of drug to be reached, but whether tumour heterogeneity impacts drug distribution...
Single-cell spatial map of cis-regulatory elements for disease-related genes in the macaque cortex
Oligomerization-competent PIF4 drives thermomorphogenesis through functional redundancy in transactivation and DNA binding
Resonant and non-resonant driving of linearly-polarized excitons in Cd3P2 magic-size clusters
DRP1 induces neuroinflammation via transcriptional regulation of NF-ĸB.
Abstract Neuroinflammation is a major pathogenic mechanism underlying neurodegenerative diseases. Understanding how neuroinflammation is regulated is critical to...
Illuminating cell states by a comprehensive and interpretable single cell foundation model
Durvalumab and cediranib with and without olaparib in recurrent ovarian cancer: a phase II proof-of-concept study
Abstract Here we report the efficacy and translational findings of durvalumab, olaparib, and cediranib (D + O + C) and of durvalumab plus cediranib (D + C) from the recurrent ovarian...
Light-programmable mechanical computing via polyaniline composite film
Abstract Mechanical computing represents a highly promising paradigm for environment-adaptive information processing. However, existing implementations are generally constrained by l...
Bridging the latency gap with a continuous stream evaluation framework in event-driven perception
Large megathrust earthquakes in cold mantle wedge corners under lawsonite blueschist facies
Semantic similarity across languages reflects neurocognitive dimensions shaped by climate
Abstract Human languages differ widely, yet they share systematic regularities in the underlying semantic representations being expressed. How such similarities and differences arise...
Prediction of thermally driven quasi-1D superionic states in carbon hydride under giant planetary conditions
Structural basis of lipid-linked galactan export by the mycobacterial ABC transporter Wzm-Wzt
Abstract Mycobacteria, including Mycobacterium tuberculosis , possess a unique cell envelope containing arabinogalactan,...