Nature Communications
Articles in this Issue
Hierarchical ceria nanoarchitecture enabling accelerated lattice oxygen activation for efficient redox reactions
MechFind: a computational framework for de novo prediction of enzyme mechanisms
Clec3b⁺ fibroblasts are the primary effectors of portal fibrosis following activation via a KLF4/periostin axis
A digital archive reveals how a funding agency cooperated with academics to support the nascent field of genomics
Large-magnitude events unlikely in induced earthquake sequences
Abstract Injecting fluids into the subsurface frequently triggers earthquakes, yet the maximum size of these events remains difficult to forecast. Earthquake frequencies are typicall...
High aspect-ratio quadrilateral flexible silica optical fibers for enhanced multi-parameter sensing
Abstract A planar silica optical fiber platform, characterized by an ultra-high aspect ratio, is introduced, termed high aspect ratio flat fiber (HARFF). Non‑circular fibers offer un...
Structural and molecular basis of specialized translation mediated by the ribosome mRNA-binding channel
Complement inhibition by a unique cluster of immunomodulatory outer surface proteins of Borrelia recurrentis
Abstract Borrelia recurrentis , the agent of louse-borne relapsing fever, causes a poverty-associated, infectious disease of high mortality....
Decorating titania with ultrasmall UiO-66-H crystallites enables quantitative photocatalytic oxidation of methane to oxygenates
Abstract Selective photocatalytic oxidation of methane to liquid oxygenates under ambient conditions remains challenging due to the inert C–H bond and propensity...
Tactile perception through fluid–solid interaction
RNA targeting therapy for a prenatally enriched potassium channel associated with severe childhood epilepsy and premature death
Abstract Dysfunction of the sodium-activated potassium channel K Na 1.1 (encoded by KCNT1)...
Four decades of intensifying Southern Ocean swells along the Pacific coast of the Americas
Abstract Swells generated in the Southern Ocean regularly impact the Pacific coasts of the Americas, with the most energetic events causing severe infrastructure damage, coastal floo...
Uridine restores oocyte quality and mitigates female reproductive aging by inhibition of ferroptosis in mice
(-)-Englerin A binding to human TRPC5 exposes an aromatic interaction network in channel activation
Abstract TRPC4/5 cation channels are polymodal cellular sensors and emerging drug targets in various human pathologies. The plant natural product (-)-englerin A (EA) is a potent, sel...
Perception and neural representation of intermittent odor stimuli in mice
Abstract Odor cues in nature are sparse and fluctuating due to turbulent transport. To investigate how animals perceive these intermittent cues, we developed a behavioral task in whi...
Uromodulin p.His36Tyr promotes macrophage pyroptosis via App-Cd74 signaling to drive renal inflammation in ADTKD
Dynamic neuronal ensembles encode burst-suppression revealed by cortex-wide optical-electrical interfaces
Abstract Burst suppression is widely observed across cortical regions during reversible or pathological unconsciousness, yet its neuronal organization remains incompletely understood...
Mapping functional non-coding variation in individual human genomes through haplotyping, multiomics, and deep learning
Abstract Most genetic variants in the human genome reside in non-coding regions, where they can perturb regulatory element activity to influence gene expression,...
Differentiation of site-specific symmetry breaking orders in Y1−xPrxBa2Cu3O6+y
Abstract Solid matter is classified through symmetry of ordering phenomena. Experimentally, this approach is straightforward, except when distinct orderings occu...
Orchestrated and dynamic nucleotide addition cycle during respiratory syncytial virus early-stage elongation
Targeting of the nuclear RNA exosome to chromatin by HP1 affects the transcriptional programs of liver cells
Abstract Heterochromatin protein 1 (HP1), a hallmark of pericentromeric heterochromatin, is a chromatin-bound regulator of co-transcriptional processes including alternative splicing...
Small heat shock and J-domain proteins direct defense against areca palm velarivirus 1 by degrading coat protein via autophagy
Distinct CA3 inputs differentially shape the learning-dependent evolution of right CA1 spatial maps
Pump-threshold-free frequency comb via cavity Floquet engineering
True cyst formation underlies persistence and drug tolerance in Tritrichomonas foetus
Abstract Tritrichomonas foetus , a protozoan parasite responsible for bovine and feline trichomonosis, has traditionally been considered to f...