Journal of the American Chemical Society
Articles in this Issue
A Versatile Tumor Microenvironment-Responsive Nanoprobe for Cancer Screening and Early Detection
Abstract It has been highly challenging to reliably detect various cancers at an early stage when tumors are just millimeters in size. To address this, we developed a tumor microenvi...
Coupling Photochromism and Charge Transport in π-Extended Arylazo Oligothiophenes and Oligothienoacenes
Abstract Developing photoresponsive molecular materials that couple efficient charge transport with robust photoswitching remains challenging because structural features enhancing on...
An Iron(V)-Oxo TAML Radical Cation Complex in Photocatalytic Water Oxidation and Electron-Transfer Reactions
Abstract Iron(V)-oxo complexes have been proposed as critical reactive intermediates in catalytic water oxidation. However, iron-oxo complexes bearing redox-active (noninnocent) liga...
One-Step Integration of Sulfonated Polymer Films with Separators for Shuttle Mitigation in Lithium–Sulfur Batteries
Abstract Interfacial polymerization (IP) offers a rapid and inexpensive method for fabricating thin polymer films. In this work, a one-step IP reaction between a triacyl chloride mon...
Reduction Inverts the Thermodynamics of the Stone–Wales Rearrangement
Abstract We demonstrate that alkali-metal doping of polycyclic aromatic hydrocarbons can reshape the potential energy surface in favor of an isomer that is disfavored in the neutral...
Scope of Ni(II)-Catalyzed Nonalternating Ethylene/Carbon Monoxide Copolymerization
Abstract The recent achievement of a nonalternating ethylene/carbon monoxide (CO) copolymerization was a long-sought breakthrough. Their in-chain keto functional groups endow the res...
Electrochemical Nitrate Reduction with Low-Index Cu Single Crystals: Selectivity Trends in Alkaline Solution
Abstract Electrochemical nitrate (NO3−) reduction is a promising pathway toward the production of ammonia (NH3). While copper (Cu) electrodes are commonly used for this reaction, the...
Two Mechanisms One Molecule: Developing a ‘Truly’ Bifunctional Degrader Targeting Rpn13 and CRBN
Abstract Targeted protein degradation (TPD) has emerged as a powerful strategy to eliminate disease-relevant proteins, yet current approaches remain largely constrained to hijacking...
Influence of Primary Coordination Sphere on Anion Rebound Selectivity in Nonheme Fe Enzyme-Catalyzed C(sp3)–H Functionalization: A Comparative Experimental and Computational Study of EgtB and ACCO
Abstract Developing enzymatic mechanisms for C–F bond formation remains a long-standing challenge. Here, we repurposed the biosynthetic nonheme Fe enzyme EgtB, which features a three...
Bidirectional Chemo-Mechanical Interface Stabilization in Perovskite Solar Cells
Abstract The interface structures between dissimilar layers in perovskite solar cells (PSCs) are prone to the concurrent occurrence of lateral (in-plane) chemical aggregation and ver...
Role of Coordination Environment in Synergistic Catalysis: A Molecular Orbital Perspective on M1M2N6 Catalysts
Abstract Visualizing the coordination environment-dependent synergistic mechanisms that govern the structural stability and adsorption behavior of dual-atom catalysts (DACs) is pivot...
Pd/Mo-Catalyzed <i>ortho</i> -Dihydroxylation of Aromatic Rings: Dual-Metal-Mediated C(sp2)–H Functionalization
Abstract We report a direct ortho-dihydroxylation protocol of benzoic acids using a Pd/Mo bimetallic catalyst and tert-butyl hydroperoxide (TBHP) as the oxidant. The Mo component sig...