Journal of Clinical Oncology
Articles in this Issue
ELEVATE: Empowered social media coaching for oncologists.
e21016 Background: Oncologists interested in building a social media presence often lack the training and tools to do so....
Immune checkpoint inhibition for advanced cutaneous squamous cell carcinoma in patients with concomitant chronic lymphocytic leukemia: Integrated single-center and national Cosmos analyses.
e21565 Background: Patients with chronic lymphocytic leukemia (CLL) have immune dysregulation and increased risk of aggres...
Outcomes of inferior vena cava filters in breast cancer patients with DVT: National Inpatient Sample–based comparative analysis.
e12763 Background: Venous thromboembolism (VTE), including deep vein thrombosis (DVT), is a frequent complication of breas...
(RW) post-progression outcomes after first-line (1L) treatment with ribociclib + an aromatase inhibitor (AI) vs AI alone in US patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2–) metastatic breast cancer (MBC).
e13044 Background: Ribociclib remains the only cyclin-dependent kinase 4/6 inhibitor to consistently demonstrate overall s...
Real-world clinical impact and prognostic utility of circulating tumor DNA in stage I–IV non–small cell lung cancer.
e20091 Background: Circulating tumor DNA (ctDNA) is an established and widely used biomarker for detection of minimal resi...
Management of pancreatic metastases from renal cell carcinoma.
e16526 Background: The pancreas is a rare site of metastases, although metastatic renal cell carcinoma (mRCC) is the most...
Genomic and biomarker landscape of MTAP deficiency in gastrointestinal cancers.
4175 Background: Genomic loss of MTAP and CDKN2A...
The impact of online CME on addressing clinical decision-making for immunotherapy in advanced squamous NSCLC.
e21002 Background: Immunotherapy (IO)-based regimens are foundational to the management of advanced squamous non-small cel...
Real-world analysis of pneumonitis risk after chemoradiation and durvalumab by chemotherapy regimen in NSCLC.
e20049 Background: Consolidation durvalumab after chemoradiation improves outcomes in patients with locally advanced NSCLC...
Distinct national mortality patterns in intrahepatic versus extrahepatic cholangiocarcinoma: A population-based study with future projections.
e16255 Background: Cholangiocarcinoma (CCA) presents a rising global health concern. United States mortality patterns diff...
Preoperative combination radiotherapy (RT) and immune checkpoint inhibitor (ICI) in early-stage breast cancer: Influence of RT and ICI treatment sequencing (NCT04454528 post-hoc analysis).
615 Background: The anti-tumor immune effects of combination radiotherapy (RT) and immune checkpoint inhibitors (ICI) are...
Generalizable cancer detection from ultra-low-pass whole-genome sequencing of cell-free DNA using a sequentially fine-tuned transformer framework.
10533 Background: Ultra-low-pass whole-genome sequencing (ULP-WGS) of cell-free DNA (cfDNA) provides a cost-effective appr...
Age-dependent survival gradients and projected future disease burden in adult acute lymphocytic leukemia: A population-based SEER analysis.
e18542 Background: Outcomes in adult acute lymphocytic leukemia (ALL) remain heterogeneous and strongly influenced by age....
Enhancing diverse participation in cancer clinical trials: Evaluating theory-based recruitment messaging and visual imagery preferences among underrepresented adults.
e24122 Background: Using multiple channels and theory-based recruitment messaging are strategies to enroll diverse audienc...
Single-agent versus combination paradigms: A systematic review and meta-analysis of the immunotherapy clinical profile in metastatic renal cell carcinoma.
e16549 Background: Immunotherapy-based combinations are established as the first-line standard of care for metastatic rena...
Lymphoma epidemiology in Syria: A 2024 analysis from the nation's primary oncology referral center.
e19042 Background: The ongoing conflict in Syria has significantly disrupted cancer surveillance, leading to a critical la...
Cancer-related overall survival for patients on durvalumab for stage III unresectable non–small cell lung cancer with PD-L1 positive and negative tumors.
8026 Background: Durvalumab improves overall survival (OS) and progression free survival (PFS) when used as consolidation...
A multicenter phase Ib/II trial of azacitidine, venetoclax, and ivosidenib in <i>IDH1</i> -mutated acute myeloid leukemia (AML).
6503 Background: Outcomes for patients with IDH1 mut AML have...
Phase II study of ceralasertib (ATR inhibitor) plus durvalumab in patients with advanced gastric cancer (AGC) who progressed on prior anti-PD-(L)1 therapy.
4062 Background: The standard first-line therapy for advanced gastric cancer (AGC) now includes immune checkpoint inhibito...
Importance of where you die: Lung cancer mortality trends in homeless-proxy settings across the U.S.
e13755 Background: Homelessness significantly impacts health, contributing to worse cancer outcomes and higher death rates...
Glucagon-like peptide-1 injectable medication uptake among United States cancer survivors with diabetes: National estimates and socioeconomic patterns from 2024.
e23094 Background: Use of glucagon-like peptide-1 (GLP-1) receptor agonists has expanded rapidly for diabetes and obesity...
Neoadjuvant apatinib plus camrelizumab in renal cell carcinoma with inferior vena cava tumor thrombus: Results of a phase II study.
4536 Background: Renal cell carcinoma (RCC) with inferior vena cava tumor thrombus (IVCTT) remains a surgically challengin...
Demographic and socioeconomic patterns of malignant melanoma in junctional nevus: An NCDB analysis.
e21572 Background: Malignant melanoma in junctional nevus (MMJN) is a rare type of cutaneous melanoma that originates in m...
Real-world efficacy and safety of photoimmunotherapy for recurrent nasopharyngeal carcinoma: A nationwide multicenter study in Japan.
6030 Background: Treatment options for locally recurrent or residual nasopharyngeal carcinoma (NPC) after definitive radio...
IL7-IL15 fusion cytokine (fusokine)–secreting iPSC-derived mesenchymal stromal cells to convert immunosuppressive into highly immune-activated tumor microenvironments (TMEs), potentiate antitumor immunity, and synergize with PD-1 inhibition in ovarian cancer.
e14522 Background: Mesenchymal stromal cells (MSCs) exhibit inherent tumor-homing properties and can be programmed to prod...