Journal of Clinical Oncology
Articles in this Issue
Assessing the true cost of infusion care: Comparing hospital chargemaster, cash, and negotiated prices for infusion CPT codes across top-ranked US hospitals.
e23186 Background: Patients in the United States often lack clear, actionable information about the prices of common outpa...
Length of stay, costs, and mortality in colon cancer: A regional comparison between the northeast and west.
e13756 Background: Colorectal cancer is a leading cause of cancer-related mortality in the United States, with an estimate...
Plasma cell-free chromatin state kinetics as a predictor of early treatment response in gastric cancer.
e16073 Background: Early and reliable assessment of treatment response across heterogeneous gastric cancer (GC) regimens r...
HMA plus venetoclax for 7- vs 14- vs 21- vs 28-day cycles in newly-diagnosed acute myeloid leukemia: ELN- and Mayo Genetic Risk–stratified analysis in 540 patients.
6525 Background: Venetoclax plus hypomethylating agent (Ven-HMA) is the standard treatment for unfit patients with newly d...
PREDICT-RD: Postoperative molecular residual disease by ctDNA surveillance in TNBC with residual disease (TBCRC-071).
TPS647 Background: Patients with residual triple-negative breast cancer (TNBC) post-neoadjuvant therapy, particularly thos...
Clinical and structural factors associated with access to stereotactic body radiation therapy (SBRT) in lung cancer.
e20104 Background: Stereotactic body radiation therapy (SBRT) is an established treatment modality for select patients wit...
Integrating genomics, imaging, and clinical data for late-onset cardiomyopathy prediction in pediatric cancer survivors: A multi-modal machine-learning comparison using St. Jude Cloud.
10018 Background: Pediatric cancer survivors face substantial risk of anthracycline- and radiation therapy (RT)-related ca...
Zirconium-engineered nanoplatform to enhance radiotherapy through NOD-like receptor-mediated pyroptosis.
e14595 Background: Radiotherapy faces significant challenges in clinical application due to tumor radioresistance and pote...
Complex segmentectomy versus lobectomy in small-sized peripheral non–small cell lung cancer: A post-hoc supplemental analysis of a multicenter, open-label, phase 3 trial (JCOG0802/WJOG4607L).
8009 Background: JCOG0802/WJOG4607L confirmed the superiority of segmentectomy on overall survival (OS) over lobectomy for...
Impact of outpatient CAR T-cell therapy administration on healthcare utilization in patients with hematologic malignancies.
1503 Background: CAR T-cell therapy has revolutionized treatment outcomes in hematological malignancies, but has tradition...
Racial disparities in maternal outcomes among pregnant patients with cancer: A National Inpatient Sample analysis.
e23244 Background: Pregnancy-associated cancer affects approximately 1 in 1,000 pregnancies. We conducted a national analy...
Overall survival benefit of doublet versus triplet BRAF inhibitor–based therapy: Insights from the BEETS study (JACCRO CC-18).
3540 Background: Cetuximab plus encorafenib, with or without binimetinib, is established as one of the standard treatment...
Effect of higher initial dose and accelerated titration of ropeginterferon alfa-2b on early hematologic and molecular responses in polycythemia vera: A meta-analysis.
e18592 Background: Ropeginterferon alfa-2b (ropeginterferon) is a mono-pegylated interferon-alpha that received FDA approv...
Real-world outcomes of microsatellite instability-high (MSI-H)/mismatch repair deficient (dMMR) biliary tract cancers (BTC).
4128 Background: Immune checkpoint inhibitors have revolutionized the treatment of microsatellite instability–high (MSI-H)...
Sociodemographic disparities in cervical cancer incidence, mortality, and disability-adjusted life years in Europe, 1990-2023.
e17520 Background: Cervical cancer remains a public health concern in Europe despite effective prevention strategies, incl...
Progressive locally advanced or metastatic radioiodine-refractory differentiated thyroid cancer (RAI-R DTC) patients treated with donafenib: A real-world study.
e18018 Background: Donafenib was approved for the treatment of RAI-R DTC patients by National Medical Products Administrat...
Concomitant radiotherapy, tremelimumab, and durvalumab for advanced NSCLC patients progressing on first-line immunotherapy: A phase 2 study (CORAL-Lung).
8583 Background: The optimal treatment for advanced NSCLC that developed resistance to immune checkpoint inhibitors (CPIs)...
Non-random patterns of multiple primary malignancies in the era of cancer survival.
10584 Background: Improved cancer therapies have increased survival, placing survivors at risk for subsequent primary canc...
Results of peripheral blood immune analysis in patients receiving immune checkpoint inhibitor therapy and correlation with immune-related adverse events.
e19568 Background: Immune-related adverse events (irAEs) result from T-lymphocyte activation induced by immune checkpoint...
Real-world patterns of PD-L1 expression, biomarker testing, and immunotherapy utilization across lung and other solid tumors in an Asian cohort.
e23380 Background: Programmed death-ligand 1 (PD-L1) immunohistochemistry (IHC) is an established enrichment biomarker gui...
An AI-enabled framework for pre-visit decision support using patient similarity analysis in melanoma.
e21533 Background: Clinical decision-making in melanoma is challenged by heterogeneous disease biology, evolving treatment...
A multi-institutional epidemiologic and oncologic profile of gastrointestinal stromal tumors in the Lebanese population.
e23508 Background: Gastrointestinal stromal tumor (GIST) is a rare type of soft tissue sarcoma that most commonly arises f...
Pan-cancer multi-omic integration for identification of clinically aggressive and potentially actionable molecular modules in breast, endometrial, and ovarian cancers.
e12610 Background: Pan-cancer analysis enable the detection of molecular alterations that are individually infrequent with...
Precision oncology in practice: Real-world multicenter experience with larotrectinib in pediatric extracranial NTRK fusion–positive tumors.
10036 Background: Gene fusions involving NTRK1/2/3 represent actionable oncogenic...
Endometrial cancer mortality among postmenopausal women in the United States, 1999-2023.
e17621 Background: Endometrial cancer occurs predominantly in postmenopausal women, driven by hormonal imbalance and metab...