Journal of Clinical Oncology
Articles in this Issue
HPV vaccination rates in New Mexico and future directions for promoting the HPV vaccine among young adults.
e22540 Background: The Human Papillomavirus (HPV) is the most common sexually transmitted infection in the U.S. and is att...
Global context modeling with vision transformers for MRI-based classification of brain tumors.
e14003 Background: Brain tumors represent a heterogeneous group of neoplasms with widely variable prognosis and treatment...
Real-world effectiveness of disitamab vedotin plus PD-1 inhibitor versus platinum-based chemotherapy as postoperative adjuvant therapy in high-risk upper tract urothelial carcinoma: A comparative study.
4611 Background: Currently, gemcitabine–platinum combination chemotherapy represents the standard adjuvant regimen followi...
Advancing equity in clinical trials through decentralized methodology: A national position statement.
e23022 Background: Regional/Rural and socially disadvantaged populations continue to face persistent barriers to clinical...
Triple M syndrome following immune checkpoint inhibitors: Clinical features and mortality drivers of a severe irAE.
e23431 Background: Triple M overlap syndrome (TMOS) is a rare but lethal immune related adverse event (irAE) characterized...
Comparative real-world outcomes of tarlatamab and lurbinectedin in relapsed extensive-stage small cell lung cancer.
8100 Background: Extensive stage small cell lung cancer is an aggressive malignancy with rapid progression and poor surviv...
Characterizing spatial tumor architecture and ECM recapitulation using an EO771 syngeneic TNBC model.
e13133 Background: Triple-negative breast cancer (TNBC) remains an aggressive malignancy with limited therapeutic options...
Tumor CTR1 expression and longitudinal serum copper assessment in breast cancer patients treated in the neoadjuvant setting.
e12629 Background: Copper is an essential nutrient required for energy production, antioxidant defense, and connective tis...
Prevalence and prognostic value of Claudin 18.2 expression in pancreatic ductal adenocarcinoma.
4188 Background: Although Claudin18.2 expression (CLDN18.2) has been investigated in pancreatic ductal adenocarcinoma (PDA...
A systematic review and meta-analysis evaluating role of AI-, ML-, and DL-based models for predicting recurrence risk after curative surgical resection of colorectal cancer liver metastases.
e15517 Background: Recurrence following curative-intent hepatic resection for colorectal cancer liver metastases (CRLM) re...
Updated safety and efficacy of puxitatug samrotecan (Puxi-Sam, AZD8205) in patients (pts) with endometrial cancer (EC) or ovarian cancer (OC): Phase 1/2a BLUESTAR study.
5515 Background: B7-H4, a transmembrane glycoprotein that negatively regulates T cells, is highly expressed in EC and OC....
Detection of mutational signatures in advanced cancer patients using clinical-grade specimens.
3137 Background: The underlying extrinsic and/or intrinsic mutational processes underlying tumor development lead to genom...
Effect of treatment delay on outcomes with adjuvant chemotherapy vs chemoradiotherapy in R1-resected biliary tract cancers.
e16267 Background: R1 margins after biliary tract cancer (BTC) resection are associated with high recurrence risk. The rol...
A phase II study to evaluate the safety and efficacy of BB-1701 in combination with sintilimab in patients with HER2 expression or mutation in locally advanced/metastatic breast cancer or NSCLC.
2632 Background: BB-1701, a HER2-targeting antibody-drug conjugate (ADC) containing eribulin, has demonstrated promising a...
A novel bispecific RDC+ADC theranostic approach to overcome trastuzumab deruxtecan resistance and tumor heterogeneity.
e15150 Background: Resistance to single-antigen HER2-targeted ADCs, such as trastuzumab deruxtecan and trastuzumab emtansi...
Survival outcomes of human epidermal growth factor receptor 2 (HER2)–amplified and HER2-mutated left-sided colorectal cancer (CRC) patients treated with anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (mAbs).
3543 Background: Current guidelines support the use of anti-EGFR mAbs in left-sided CRCs without mutations in...
Diagnostic accuracy of urine-based HPV testing for cervical neoplasia and cancer: A landmark systematic review and meta-analysis.
e17506 Background: Urine-based human papillomavirus (HPV) testing offers a non-invasive screening alternative that could i...
Teliso-V monotherapy and EGFR-TKI combinations in c-Met–over-expressing NSCLC: A systematic review and meta-analysis.
e20714 Background: c-Met protein over-expression is frequent in non-small cell lung cancer (NSCLC) and is linked to poor p...
Heart failure in hospitalizations for hematologic malignancies versus solid tumors: National burden and inpatient outcomes, 2018-2022.
11074 Background: Heart failure (HF) is a common and morbid comorbidity in oncology. Whether HF burden and prognosis diffe...
Recovery with residual disparities: Real-world patterns of platinum chemotherapy use after the 2023 drug shortage.
1562 Background: The 2023 national shortages of cisplatin and carboplatin disrupted standard cancer treatment across multi...
Sleep disorder diagnosis prevalence among adult cancer patients.
e24113 Background: Sleep is commonly impacted by cancer diagnosis and treatment. Poor sleep is consistently reported to be...
Clinico-transcriptomic risk stratification to guide abiraterone treatment intensification in high-risk prostate cancer: A combined analysis of NRG/RTOG 9202, 9413, 9902, and 0521.
5000 Background: Outcomes for some patients with ≥high-risk localized prostate cancer (HR-PCa) who receive radiati...
Neoadjuvant chemoimmunotherapy before chemoradiation vs chemoradiation alone for stage IIB-IIIC1 carcinoma of the cervix: A phase II open-label randomized controlled trial (NeoCHIMERA).
TPS5631 Background: Locally advanced cervical cancer (FIGO 2018 stages IIB–IIIC1) remains a major cause of cancer-related...
Oncologic safety and patient-reported outcomes of sentinel lymph node biopsy omission in early breast cancer: A meta-analysis of randomized controlled trials.
e12618 Background: Sentinel lymph node biopsy (SLNB) has replaced axillary lymph node dissection for axillary staging in c...
Race-associated clinicogenomic predictors in non-small cell lung cancer treated with immune checkpoint inhibitors.
8557 Background: PD-L1 low and STK11 mutation associate with immune checkpoint inhibitor (ICI) resistance in non-small cel...