Journal of Clinical Oncology
Articles in this Issue
Multi-study genomic survival modeling and gene panel recalibration across heterogeneous cohorts.
e13671 Background: Gene expression–based prognostic models and multigene panels are widely used for risk stratification in...
Diagnostic and predictive utility of peritoneal tumor DNA in gastroesophageal cancer: A prospective multicenter study.
4101 Background: Gastric and gastroesophageal cancers (G/GEC) commonly spread to the peritoneum. Accurate peritoneal stagi...
Tumor microenvironment phenotypes and survival in fibrolamellar carcinoma: An exploratory study.
4150 Background: Fibrolamellar carcinoma (FLC) is a very rare liver cancer affecting children, adolescents, and young adul...
Safety, immunogenicity, and efficacy of Ad5.F35-GUCY2C-PADRE vaccine in patients with GI cancers at high risk of relapse: Results from a phase 2A trial.
3617 Background: Guanylyl cyclase C (GUCY2C) is an intestinal tumor antigen ectopically expressed in some gastroesophageal...
Rural-urban disparities in demographics, clinical characteristics, and hospitalization burden among young non-smoking adults with lung cancer in the United States.
e20645 Background: Recent reports indicate a rise in lung cancer incidence among young non-smokers, yet rural-urban differ...
Evaluating trust in health information sources among persons with a cancer diagnosis: An analysis of the HINTS database.
e23342 Background: Trust in health information sources plays a critical role in how patients understand and adhere to thei...
Emiltatug ledadotin (Emi-Le), a B7-H4–directed antibody-drug conjugate (ADC), in patients with aggressive adenoid cystic carcinoma (ACC): Phase 1 interim analysis.
6010 Background: ACC is a rare cancer that typically arises in the salivary glands but can affect various organs. About 40...
Real-world comparison of remission status in newly diagnosed multiple myeloma treated with daratumumab-based versus bortezomib-based first-line therapy.
e19572 Background: The introduction of CD38 monoclonal antibodies has transformed the frontline management of newly diagno...
Direct oral anticoagulants versus low-molecular-weight heparin for venous thromboembolism in primary brain tumors: A TriNetX real-world analysis.
2054 Background: Venous thromboembolism (VTE) is a common complication in patients with primary brain tumors and is associ...
Thrombotic events in patients receiving immune checkpoint inhibitors: Incidence, risk factors, and prognostic outcomes from a retrospective cohort study.
e24155 Background: Immune checkpoint inhibitors (ICIs) have transformed cancer outcomes across multiple malignancies. Howe...
Comparative evaluation of the diagnostic value of microRNAs for early colorectal cancer detection in adults: Results of a systematic review and network meta-analysis.
e15530 Background: Circulating microRNAs (miRNAs) are promising non-invasive biomarkers for colorectal cancer (CRC), but t...
Prediction of pathologic response using a taxane-based gene expression signature in RNA-sequencing data from breast cancer patients receiving neoadjuvant therapy.
549 Background: Taxanes are frequently used in both early and advanced breast cancer, but their use has not yet been guide...
Survival and socioeconomic disparities in the elderly population with mycosis fungoides and Sézary syndrome: A comparative analysis of 2,690 patients by facility type.
7069 Background: Mycosis fungoides (MF) and Sézary syndrome (SS) are rare T-cell malignancies (0.26 and 0.36/100,000 perso...
Revumenib as maintenance for AML following allogeneic stem cell transplantation.
6505 Background: Relapse after allogeneic stem cell transplantation (SCT) remains common in acute myeloid leukemia (AML)....
Systemic antibiotic exposure and outcomes of immune checkpoint inhibitors in non–small cell lung cancer.
e20602 Background: Immune checkpoint inhibitors (ICIs) have transformed the management of solid tumors, particularly non–s...
Phase II open-label trial of neoadjuvant immunotherapy in combination with CAPOX for resectable non-metastatic proficient mismatch repair (pMMR) colon cancer: NICER study.
TPS2691 Background: Colorectal cancer (CRC) is the third most common malignancy worldwide. Immune checkpoint inhibition ha...
Association of baseline protein–energy malnutrition with mortality and healthcare utilization in patients with hepatocellular carcinoma treated with VEGF-based systemic therapy.
e16166 Background: Patients with hepatocellular carcinoma (HCC) frequently have advanced liver disease and frailty at the...
QUINTESSENTIAL-2: A phase 3 study of arlocabtagene autoleucel versus standard of care in adult patients with relapsed and refractory multiple myeloma (RRMM) exposed to lenalidomide.
TPS7577 Background: Despite advances in multiple myeloma (MM) treatment, most patients (pts) will relapse, highlighting th...
Prevalence of post-traumatic stress disorder and associated factors among adult sarcoma patients.
11557 Background: A cancer diagnosis and treatment can be extremely stressful and even traumatic for sarcoma patients. How...
Immune checkpoint inhibitor adoption, timing, and survival in an urban lung cancer cohort: A landmark analysis.
e20697 Background: Although immune checkpoint inhibitors (ICIs) improve survival in randomized trials, real-world use is s...
Disproportionate reporting of severe gastrointestinal injury with ruxolitinib among JAK inhibitors in myeloproliferative neoplasms: A FAERS pharmacovigilance analysis.
e18600 Background: Janus kinase (JAK) inhibitors are cornerstone therapies for myeloproliferative neoplasms (MPNs). Althou...
Burden and trends of cancer and attributable risk factors in women, 1990 to 2023, with projections of mortality to 2050.
e22624 Background: Cancer (CA) is a leading cause of premature mortality and disability in women worldwide. Women specific...
Detection, quantification, and subtyping of adenoid cystic carcinoma (ACC) using methylation from liquid biopsies.
6118 Background: Despite the common indolent behavior of ACC, some patients will experience aggressive disease with short...
Implementation of a multi-cancer early detection (MCED) test in a private practice: Adoption, performance, and repeat-testing patterns.
10532 Background: Century City Medical Management (CCMM), a network of private primary care practices, implemented MCED te...
Lung cancer navigation pilot: Preliminary results of nurse outreach support for lung cancer patients enrolled in the EOM.
e13580 Background: Oncology practices struggle with reducing unnecessary ED visits and hospitalizations. This is an import...