Journal of Clinical Oncology
Articles in this Issue
Myxoid leiomyosarcoma: A population-based NCDB analysis.
e17611 Background: Myxoid leiomyosarcoma is a rare malignant smooth muscle tumor characterized by abundant myxoid stroma a...
ICONIC (Improving Outcomes Through Collaboration in Osteosarcoma): Insights from a national prospective cohort trial for newly diagnosed osteosarcoma patients.
11524 Background: There has been little change in osteosarcoma (OS) treatment over the last two decades. Understanding man...
Efficacy and safety of telpegfilgrastim in the prophylaxis of chemotherapy-induced neutropenia in breast cancer patients: A retrospective study.
e12515 Background: Chemotherapy-induced neutropenia (CIN) is a common complication during cancer chemotherapy, leading to...
An alternative approach to limiting surgical and radiation stress in patients with glioblastoma.
2062 Background: While neuro-oncology has seen global advances in high-tech diagnostics and treatments for brain tumors, t...
Guard-01: A randomized, open-label trial of efbemalenograstim alfa as primary prophylaxis for neutropenia during definitive concurrent chemo-radiotherapy.
12060 Background: Concurrent chemoradiotherapy (CCRT), a curative cornerstone for locally advanced malignancies, exerts sy...
USP10 activity as sensitizer of lung adenocarcinoma to immune checkpoint inhibitors: Upregulating PD-L1 via the ANT3-mediated activation of the cGAS-STING pathway.
8542 Background: Although immune checkpoint inhibitors (ICIs) have reshaped the treatment landscape for advanced lung aden...
Empowering multidisciplinary teams in cancer survivorship: Results from the ASCO Project ECHO survivorship program in Brazil.
11096 Background: As the number of cancer survivors increases in Brazil, access to structured survivorship education for h...
Treatment outcomes with pembrolizumab and chemotherapy in metastatic metaplastic triple-negative breast cancer: Data from a central European cohort.
e13119 Background: Metaplastic triple-negative breast cancer (MpTNBC) is a rare and clinically aggressive subtype of breas...
Efficacy and safety of cadonilimab (CD) in combination with disitamab vedotin (RC48) or nab-paclitaxel (NP) in the treatment of recurrent or metastatic cervical cancer (r/mCC): A prospective, double-cohort, multicenter, open-label, phase II clinical study.
5526 Background: The prognosis for patients(pts) with r/mCC is poor. The available second-line treatment regimens are limi...
Final results of the phase III OCTAVA trial: Clinical benefit of low-dose anti–CTLA-4 plus anti–PD-1 combination vs anti–PD-1 monotherapy in unresectable or metastatic melanoma.
9544 Background: BCD-217-2/OCTAVA is an international, multi-center, randomized, double-blind, placebo-controlled phase II...
An intervention in disguise: An immersive care model for families where a parent has a brain tumor.
e13551 Background: Having a parent with brain cancer deeply impacts the family unit, leading to increased isolation and lo...
Real-world experience of a pediatric precision oncology protocol utilizing paired somatic and germline sequencing at a single institution: Interim analysis.
10008 Background: While most pediatric oncology patients are cured with upfront therapy, outcomes for patients with metast...
Landscape of the immune microenvironment in malignant pleural effusion from EGFR-TKI-resistant NSCLC.
e20532 Background: Malignant pleural effusion (MPE) is a poor prognostic factor in non-small cell lung cancer (NSCLC), whi...
Platinum-based chemotherapy in early-stage, high-risk, triple-negative breast cancer: A systematic review and meta-analysis of randomized trials.
529 Background: The clinical benefit of adding platinum agents to adjuvant chemotherapy for early-stage triple-negative br...
Updated efficacy and safety of olverembatinib (HQP1351) as second-line therapy in patients with chronic-phase chronic myeloid leukemia (CP-CML).
6510 Background: Olverembatinib is a third-generation BCR::ABL1 tyrosine kinase inhibitor (TKI) approved in China for chro...
Effect of neoadjuvant radiotherapy combined with surgery on long-term prognosis of patients with centrally located hepatocellular carcinoma: A machine learning and propensity score weighting analysis.
e16259 Background: Primary liver cancer is the sixth most common malignancy globally and the third leading cause of cancer...
When disaster strikes: A scoping review of climate-resilience toolkits relevant to cancer care delivery.
e23198 Background: External disruptions, such as extreme weather and infrastructure failures,are increasingly undermining...
Early versus delayed biologic therapy for immune checkpoint inhibitor–associated colitis: A propensity-matched real-world analysis.
e24204 Background: Immune checkpoint inhibitor (ICI)–associated colitis is a clinically significant immune-related adverse...
Sequential use of antibody-drug conjugates in advanced breast cancer: A real-world study based on HER2 status.
e13020 Background: The optimal sequencing strategy for antibody-drug conjugates (ADCs) following progression on prior ADC...
Cardiac safety of L-annamycin at high cumulative anthracycline exposure: Pooled analysis.
12025 Background: Anthracyclines are widely used chemotherapeutic agents but limited by dose-dependent cardiotoxicity and...
The complementary anti-cancer and analgesic properties of the natural product barettin.
e15129 Background: Chemotherapy induced peripheral neuropathy (CIPN) is one of the most common side effects of chemotherap...
Alcohol and cancer risk: A review of messaging content on websites of medical, cancer, government, and nonprofit organizations and alcohol companies.
e22508 Background: Alcohol is a risk factor for multiple cancers, yet there is limited awareness of this risk relationship...
Trends in U.S. pneumonia-related admissions among patients with multiple myeloma (2006–2022).
e19535 Background: Despite improvements in survival due to novel therapies, patients with multiple myeloma (MM) experience...
Clinical profile, treatment patterns, and survival outcomes of multiple myeloma patients in the Middle East: Real-world data from Bahrain.
e19576 Background: Real-world data from the Middle East in myeloma is limited, despite unique demographic factors that may...
Influence of genetic ancestry on UV mutational signatures linked to immunotherapy response in melanoma, beyond TMB.
3087 Background: Melanoma is a UV-driven malignancy with substantial biological heterogeneity, yet genomic profiling effor...