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Correction: RIPC improves myocardial injury by promoting mitochondrial protection via the PGC-1α/Nrf2 pathway

ERK promotes miR34a/ISOC1 signaling to enhance all trans retinoic acid-induced myeloid differentiation in acute promyelocytic leukemia

ARMH3 acts as a central scaffold at the Golgi/TGN through interactions with Arl5, GBF1, and PI4KB

Integrating condensates into protein lifespan – From birth to death

Erythroferrone antagonism of BMPs is governed by a composite heparin-binding motif

TRAIP promotes the development of papillary thyroid cancer by inhibiting TRAF2-mediated BRAF ubiquitination

Tamoxifen induces region-specific osteocytic recombination and transiently alters bone structure in Dmp1-Cre-ERT2 mice

Correction: Glyceraldehyde-3-phosphate dehydrogenase/1,3-bisphosphoglycerate-NADH as key determinants in controlling human retinal endothelial cellular functions: Insights from glycolytic screening

An isotype-specific phosphorylation of Hsp90 rewires co-chaperone regulations

Waiting time distribution and multifractality analysis of solar flares

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Quantum Kinetic Uncertainty Relations in Mesoscopic Conductors at Strong Coupling

General theoretical framework linking macroscopic stress to microscopic strand conformations in unentangled elastomers

Possible solution to the gallium anomaly moving beyond the leptonic wave-function factorization

Magnetic turbulence boosts supernova signals of axionphoton conversion

Promote or prevent? A regulatory focus perspective on managerial risk taking

This study examines the heterogeneity of CEOs’ risk attitudes and how fixed versus variable compensation components shape their strategic risk-taking, as part of corporate governance policy. Building on psychological Regulatory Focus Theory (RFT) and established management frameworks, we developed a conceptual model with six hypotheses. We applied a validated Polish Linguistic Inquiry and Word Count (LIWC) dictionary to measure CEOs’ promotion and prevention focus through content analysis of their shareholder letters. Our dataset covers 82 companies listed on the Warsaw Stock Exchange (WSE) from 2011 to 2020, analyzed using longitudinal panel data. The results confirmed that a CEO’s regulatory focus is a significant motivational factor in strategic risk-taking. Promotion-focused CEOs tend to pursue bolder, riskier decisions, increasing the firm’s strategic risk, whereas prevention-focused CEOs are more cautious and inclined to mitigate risk, aligning with prior findings in the literature. Moreover, these relationships are moderated by compensation structure. Higher fixed salaries are associated with reduced strategic risk, reinforcing risk aversion, while larger annual bonuses are associated with greater risk-taking. In particular, fixed compensation strengthened the natural risk-avoidant tendencies of prevention-focused CEOs, suggesting that higher guaranteed income reinforces a cautious strategy. Unexpectedly, large annual bonuses did not temper the risk appetite of promotion-focused CEOs; instead, bonuses amplified their risk-taking, indicating that intrinsic motivation can outweigh extrinsic incentives for risk moderation. These findings underscore the need for tailoring executive compensation policies to individual CEOs’ risk preferences. Fixed salaries may temper excessive risk-taking in promotion-focused CEOs, while performance-based bonuses may motivate otherwise cautious, prevention-focused CEOs to undertake strategic risks. Such insights are valuable for refining corporate governance strategies in European public firms, especially in Poland, to better align CEO behavior with shareholder interests.

Correction: The spatial spillover effect and its attenuation boundary of urban economy on port efficiency

Applications of the Behavior Change Wheel in promoting physical activity among children and adolescents: A scoping review

Background Physical inactivity among children and adolescents remains a major global public health concern, yet the ways in which behavioral theory is applied to inform physical activity (PA) interventions are often insufficiently described. The Behavior Change Wheel (BCW) model provides a systematic framework for linking behavioral determinants to intervention content, but its application in PA promotion for this population has not been comprehensively mapped. Methods This scoping review was conducted in accordance with the Joanna Briggs Institute methodology and reported following the PRISMA-ScR guideline. Seven electronic databases were searched for studies published since 2011 that explicitly applied the BCW to promote PA among children and adolescents. Data were charted on study characteristics, targeted components of the Capability, Opportunity, and Motivation-Behavior (COM-B) model, BCW intervention functions, behavior change techniques, and implementation outcomes. Results Fifteen studies met the inclusion criteria. Most applications focused on intervention development, co-design, or feasibility rather than effectiveness evaluation. Psychological capability and reflective motivation were the most frequently targeted COM-B components, and education, training, and enablement were the dominant intervention functions. Commonly used behavior change techniques included goal setting, action planning, self-monitoring, feedback, and social support. Functions involving coercion or restriction were rarely used. Reporting of implementation outcomes was inconsistent, with limited attention to reach, penetration, and sustainability. Conclusions In studies using the BCW framework, PA interventions for children and adolescents predominantly emphasize individual-level self-regulation strategies, with less focus on opportunity-level change and implementation sustainability. Greater transparency in theoretical mapping and stronger integration of implementation considerations are needed to enhance the translation of theory-based interventions into practice.

‘Us and them’: A realist interview study exploring how and why health system factors influence dentists’ participation in state funded, contracted primary dental care for low-income populations in Ireland

Objectives To identify and explain the health system factors influencing private general dental practitioners (GDPs) engagement in state-funded, contracted primary oral healthcare for low-income adults in Ireland, in which circumstances, for which groups, how and why. Methods Nineteen realist interviews were conducted with frontline GDPs, health system actors and academic subject experts from Ireland and elsewhere. Collected data were then transcribed, coded, and analysed to generate context–mechanism–outcome configurations (CMOCs) and develop an overarching realist programme theory to explain causation. Results Thirteen individual and abstracted CMOCs were crafted and subsequently consolidated into five high level CMOCs. GDPs’ engagement with state funded care is influenced by a myriad of complex health system contextual factors. These include low political and resource commitment to oral health; cost containment measures characterised by limited and outdated baskets of care and low remuneration; overtly bureaucratic oversight or contract administrative processes; adversarial communications and the absence of consultative mechanisms between the health system and GDPs. Other factors such as oral healthcare ‘market’ dynamics, GDPs’ professional networks and community ties can also influence engagement in state care. Conclusion As Ireland looks to reform its primary oral healthcare system to widen population access to care and meet national oral health policy and WHO commitments on oral health, the findings of this study provide health system leaders with evidence to leverage system change and increase or sustain GDPs’ engagement in state care. Leveraging such change has the potential to improve access to care for vulnerable populations and reduce oral health inequalities.

Incremental diagnostic yield of bone scintigraphy after standard radiologic imaging in patients with fall trauma at a Level I trauma center

Objective This study aimed to evaluate the incremental diagnostic yield of bone scintigraphy (BS) performed after standard radiologic imaging (SRI) modalities, including radiography, computed tomography, and magnetic resonance imaging, in patients with fall trauma presenting to a Level I trauma center. Methods Three hundred eight patients with fall trauma who underwent BS after SRI were retrospectively enrolled. The presence and number of bone injuries across six skeletal regions were evaluated using both SRI and BS. Bone injuries were evaluated according to three imaging-based categories: SRI alone, SRI − /BS + , and SRI + BS. Imaging-derived bone parameters included the total number of regions with bone injuries, the total number of injured bones, and the Imaging Bone Index (IBI) score. Correlations between these imaging-derived bone parameters and four trauma scores were analyzed, and differences in imaging-derived bone parameters were examined according to the cutoff values of each trauma score. Results The imaging-derived bone parameters in the SRI + BS category were significantly higher than those in the SRI alone category. Imaging-derived bone parameters in both the SRI alone and SRI + BS categories showed significant correlations with all trauma scores, with significantly stronger correlations for the total number of injured bones and IBI scores in the SRI + BS category. Patients with severe trauma exhibited significantly higher imaging-derived bone parameters in the SRI − /BS+ category. Conclusions Performing BS after SRI provided incremental diagnostic yield by detecting additional bone injuries not identified on preceding SRI and yielded quantitative imaging-derived bone parameters associated with trauma severity in this Level I trauma center cohort of patients with fall trauma.