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Factors influencing ankle alignment changes following medial unicompartmental knee arthroplasty: Preoperative knee and ankle deformities and extent of knee alignment correction

PLoS ONE Han-Ting Shih, Shun-Ping Wang, Cheng-Hung Lee et al. Mar 14, 2025 DOI: 10.1371/journal.pone.0318677

Introduction The impact of medial unicompartmental knee arthroplasty (MUKA) on ankle alignment is not well-studied. This study aims to investigate the changes in ankle alignment following MUKA and identify the influencing factors. Materials and Methods A retrospective analysis included 175 patients undergoing MUKA between 2018 and 2020. Patients were categorized into varus (n =  113) or valgus (n =  62) ankle groups based on preoperative ankle deformities. Preoperative and postoperative full-length standing radiographs were used for radiographic measurements. Results Following MUKA, significant differences in the change in tibial plafond-talus angle (PTA) were observed between the groups, with the varus ankle group showing a change of -0.71 ±  0.82° and the valgus ankle group showing a change of 0.08 ±  0.94° (p <  0.001). In the varus ankle group, the tibial plafond-ground angle (PGA) increased from -3.65 ±  4.22° preoperatively to -0.51 ±  4.52° postoperatively (p <  0.001), talus-ground angle (TGA) increased from -5.28 ±  4.32° to -1.32 ±  4.74° (p <  0.001), and PTA decreased from 1.52 ±  1.04° to 0.81 ±  1.12° (p <  0.001). In the valgus ankle group, PGA increased from -5.44 ±  4.39° to -1.43 ±  4.63° (p <  0.001) and TGA increased from -4.55 ±  4.24° to -0.59 ±  4.47° (p <  0.001), but PTA did not show a significant change. Ankle alignment change significantly correlated with preoperative joint line convergence angle (JLCA), preoperative medial proximal tibial angle (MPTA), preoperative PGA, preoperative TGA, preoperative PTA, hip-knee-ankle angle (HKA) changes, and bearing thickness. Conclusions MUKA significantly corrects the majority of ankle alignment towards a more neutral position. The extent of ankle alignment correction is influenced by preoperative knee and ankle joint deformities, as well as the degree of knee alignment correction.

“You do need each member of the team to bring that next piece of the puzzle”: Allied health professionals’ experience of interprofessional complex care in hospital settings

PLoS ONE Felice Borghmans, Venesser Fernandes, Stella Laletas et al. Mar 14, 2025 DOI: 10.1371/journal.pone.0317799

This study explores the experiences of allied health professionals who work in interprofessional hospital complex care teams. The aim of the study was to identify factors influential to meaningful clinician experiences in these contexts. Increase in interprofessional complex care in hospital settings reflects rising population health complexity. Furthermore, growth in these models coincides with a heightened focus on health system efficiency due to rising healthcare costs, resource constraints, and health workforce shortfalls. Combined, these issues constitute a ‘wicked problem’. However, research exploring the experiences of clinicians working under these conditions is limited, exposing the knowledge gap of interest to this study. Using a qualitative approach, in-depth interviews were conducted with allied health professionals engaged in hospital-based interprofessional complex care, and their narratives were analysed according to the conceptual framework of complex adaptive phenomenology. The study identified four interconnected themes: workplace culture and leadership, interprofessional practice, healthcare ethics, and the ambiguity of complex care. Furthermore, the notion of ‘empowerment of self and others’ was a continuous thread throughout, which appeared essential to effective interprofessional practice. The study showed how the clinician experience provides a window to the functioning of a healthcare system and the bearing of experience on healthcare efficiency and sustainability. Recommendations include developing a more balanced approach to ‘efficiency’ in policy settings, implementing structured leadership development programs within the allied health workforce, empowering under-graduate practitioners through education to work effectively with uncertainty, and increasing research into the clinician experience of interdisciplinary complex care practice.

RAC1 promotes the occurrence and development of tongue squamous cell carcinoma by regulating RAC1/PAK1/LIMK1 signaling pathway

Scientific Reports Zongxuan He, Kai Song, Hongyu Han et al. Mar 14, 2025 DOI: 10.1038/s41598-025-92538-z

Self-reported myopia and age-related cataract: a two-sample Mendelian randomization study

Scientific Reports Huan Liu, Feiyan Wang, Jing Wei Mar 14, 2025 DOI: 10.1038/s41598-025-93564-7

Experimental and theoretical investigation into the decomposition mechanism of 3,5-dimethyl-4-hydroxyphenylpentazole

Scientific Reports Lei Chen, Chao Gao, Chong Zhang et al. Mar 14, 2025 DOI: 10.1038/s41598-025-93972-9

Intelligent prediction system for surface movement and deformation in the subsequent filling mining of inclined, thick, and large ore

Scientific Reports Xinxin Huang, Chen Wang, Xuyu Li et al. Mar 14, 2025 DOI: 10.1038/s41598-025-93123-0

Subjective probability is modulated by emotions

Scientific Reports Lara Abel, Eric Schulz, Jonathan D. Nelson Mar 14, 2025 DOI: 10.1038/s41598-025-92230-2

Abstract Information about risks and probabilities is ubiquitous in our environment, forming the basis for decisions in an uncertain world. Emotions are known to modulate subjective probability when probabilistic information is desired (as in gambles) or undesired (as in risks). Yet little is known about the role of emotions in shaping the subjective probability of affectively neutral events. We investigated this in one correlational study (Study 1, N = 162) and one experimental study (Study 2, N = 119). As predicted, we found that participants higher in emotional dominance were more conservative in their probability estimates, avoiding the extremes. Remarkably, this pattern also transferred to realistic risk assessments. Furthermore, respondents’ tendency to use the representativeness heuristic as a proxy for probability was increased in high dominance individuals. Our findings suggest that emotional dominance may be a unifying construct explaining previously reported effects of emotions on probabilistic cognition.

Publisher Correction: Molecular diversity and genetic potential of new maize inbred lines across varying sowing conditions in arid environment

Scientific Reports Ahmed A. Galal, Fatmah A. Safhi, Nora M. Al Aboud et al. Mar 14, 2025 DOI: 10.1038/s41598-025-93231-x

USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance

Scientific Reports Bo Zhou, Jie Li, Shuai Wu et al. Mar 14, 2025 DOI: 10.1038/s41598-025-93029-x

Functional and molecular single-cell analyses implicate PRDM14 in the initiation of B cell leukemia in mice

Scientific Reports Lauren J. Tracey, Mahmoud El-Maklizi, Dustin J. Sokolowski et al. Mar 14, 2025 DOI: 10.1038/s41598-025-93043-z

Space disinfection using TiO2 photocatalyst reduces the incidence of febrile neutropenia in cancer patients

Scientific Reports Kazuhide Iizuka, Heihachiro Ochiai, Yoshikazu Iizuka et al. Mar 14, 2025 DOI: 10.1038/s41598-024-82229-6

Experimental study on the mechanism of rockburst in tunnel construction by drilling and blasting construction in high ground stress stratum

Scientific Reports Bin Wang, Huaqiao Xu, Qinghe Zhang et al. Mar 14, 2025 DOI: 10.1038/s41598-025-93551-y

Sexual dimorphism and morphological integration in the orchid bee brain

Scientific Reports Denise Yamhure-Ramirez, Peter C. Wainwright, Santiago R. Ramírez Mar 14, 2025 DOI: 10.1038/s41598-025-92712-3

Abstract Sex-specific behaviours are common across animals and often associated with sexual dimorphism in the nervous system. Using micro-CT scanning we standardized sex-specific brain atlases and tested for sexual dimorphism in the brain of the orchid bee Euglossa dilemma , a species with marked sex differences in social behaviour, mating strategies and foraging. Males show greater investment in all primary visual processing neuropils and are uniquely integrated with the central complex, evidenced by a strong positive covariation. This suggests that males invest more on locomotor control, flight stability and sky-compass navigation which may have evolved in response to sex-specific behaviours, like courtship display. In contrast, females have larger mushroom bodies that strongly and positively covary with the optic lobes and have increased volume of the Kenyon cell cluster, implying greater capabilities for visual associative memory. We speculate this is an adaptation to social and nest-building behaviours, and reliance on learning visual landmarks required for central place foraging. Our study provides the first record of sexually dimorphic morphological integration in the brain of an insect, an approach that revealed sex-specific brain traits that lack an apparent morphological signal. These subtle differences provide further evidence for the causal link between brain architecture and behaviour.

Author Correction: Energy optimization and plant comfort management in smart greenhouses using the artificial bee colony algorithm

Scientific Reports Muhammad Jawad, Fazli Wahid, Sikandar Ali et al. Mar 14, 2025 DOI: 10.1038/s41598-025-93229-5

Range dependent Hamiltonian algorithms for numerical QUBO formulation

Scientific Reports Hyunju Lee, Kyungtaek Jun Mar 14, 2025 DOI: 10.1038/s41598-025-93552-x

Prism and Maddox rod test as a reliable tool for surgical targeting in small-angle AACE

Scientific Reports Longxiang Huang, Jinghan Wu, Huihang Wang et al. Mar 14, 2025 DOI: 10.1038/s41598-025-93791-y

Publisher Correction: Scattering of Sculpted Light in Intact Brain Tissue, with implications for Optogenetics

Scientific Reports Itia A. Favre-Bulle, Daryl Preece, Timo A. Nieminen et al. Mar 14, 2025 DOI: 10.1038/s41598-025-92455-1

The impact of gamma interferon on BK virus candidate microRNAs and related miRNAs in kidney transplant patients with BK infection

Scientific Reports Maryam Changizi, Gholamreza Motalleb, Ramin Yaghobi et al. Mar 14, 2025 DOI: 10.1038/s41598-025-93503-6

Synergistic effects of biochar and plants can reduce greenhouse gas emissions from salt affected soil

Scientific Reports Dwarika Bhattarai, Shailesh Pandit, Rojina Kafle et al. Mar 14, 2025 DOI: 10.1038/s41598-025-93198-9

YTHDC1 negatively regulates UBE3A to influence RAD51 ubiquitination and inhibit apoptosis in colorectal cancer cells

Scientific Reports Mingwei Gao, Yueguang Wu, Li Zhang et al. Mar 14, 2025 DOI: 10.1038/s41598-025-92925-6