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Sex-specific association between maternal childhood adversities and offspring’s weight gain in a Brazilian cohort
Abstract Maternal adverse childhood experiences (ACEs) are linked to negative health and developmental outcomes in offspring. However, whether maternal ACEs influence infant weight gain in the first months of life, and if this effect differs by infant sex, remains unclear. This study included 352 full-term newborns from low-risk pregnancies and their mothers in low-income settings in Brazil. Anthropometric data (weight, length, head circumference) and other information (feeding type, offspring sex, family income) were collected at delivery (W0), discharge (W1), and up to 8 weeks postpartum (W2). ACEs were assessed using the CDC-Kaiser Questionnaire, and weight gain was calculated as the difference between W2 and W1, divided by the number of days between measurements. The association between maternal ACEs and offspring weight gain was positive only in male offspring (unstandardized coefficient (male) = 1.82, SE = 0.438, p < 0.001); for each 1-point increase in the ACEs score (e.g., from 0 to 1), weight gain increased by 1.8 g/day. These findings indicate that maternal ACEs are associated with increased weight gain in male infants during the first two months of life, potentially increasing the risk of future obesity. Further research is required to investigate the underlying biological mechanisms and their neurodevelopmental implications.
Intelligent control algorithms for posture and height control of four-leg hydraulic supports
AI learns from chromatin data to uncover gene interactions
Comparison of outcomes with and without intrastent placement during PMS surgery
Abstract To assess the efficacy of using a nylon suture as a stent in the PreserFlo MicroShunt (PMS) lumen to prevent postoperative hypotony, 59 eyes that underwent PMS implantation with follow-up for > 6 months were analyzed. Patients were divided into no intrastenting (NST) and intrastenting (ST) groups, with the ST group subdivided into 9 − 0 nylon suture fully placed (9 F), 9 − 0 nylon suture placement in only half of the lumen (9 H), 10 − 0 nylon suture fully placed (10 F), and 10 − 0 nylon suture placement in only half of the lumen (10 H). The distribution was as follows: 23 eyes in the NST group, 10 in the 9 F group, 9 in the 9 H group, 11 in the 10 F group, and 6 in the 10 H group. No significant differences were observed in preoperative and 6-month postoperative intraocular pressure, number of glaucoma medications, or cumulative survival rate between groups. Postoperative hypotony occurred in 13 eyes (56.5%) in the NST group, one (2.78%) in the ST group (p = 0.00014). Post-intrastent removal, hypotony occurred in 6 eyes (16.7%) in the ST group. These findings suggest that intrastent placement effectively prevents postoperative hypotony, regardless of nylon suture diameter or insertion length; however, timing is crucial as hypotony may occur after removal.
Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals
Relationship between androgen receptor and androgen receptor-related protein expression in breast cancers focusing on morphologically identified carcinoma with apocrine differentiation
Deformation mechanism and damage energy evolution of coal body under different gas pressures based on the energy principle
The longitudinal association between multiple cardiometabolic diseases, socioeconomic status, and depressive symptoms in China
Extracting rates and activation free energies of martensitic transitions using nanomechanical force statistics: theory, models, and analysis
Individual and sex differences in frontloading behavior and approach- avoidance conflict preference predict addiction-like ethanol seeking in rats
LINC00626 drives tamoxifen resistance in breast cancer cells by interaction with UPF1
Assessing blood flow in uterine fibroids using intravoxel incoherent motion imaging compared with dynamic contrast-enhanced MRI
Conformational protection of molybdenum nitrogenase by Shethna protein II
Transient cortical beta-frequency oscillations associated with contextual novelty in high density mouse EEG
Abstract Beta-frequency oscillations (20–30 Hz) are prominent in both human and rodent electroencephalogram (EEG) recordings. Discrete epochs of beta (or Beta2) oscillations are prevalent in the hippocampus and other brain areas during exploration of novel environments. However, little is known about the spatial distribution and temporal relationships of beta oscillations across the cortex in response to novel contexts. To investigate this, mice fitted with 30-channel EEG-style multi-electrode arrays underwent a single recording session in a novel environment. While changes to spectral properties of cortical oscillations were minimal, there was a profound increase in the rate of beta bursts during the initial part of the recording session, when the environment was most novel. This was true across the cortex but most notable in recording channels situated above the retrosplenial cortex. Additionally, novelty was associated with greater connectivity between retrosplenial areas and the rest of the cortex, specifically in the beta frequency range. However, it was also found that the cortex in general, is highly modulated by environmental novelty. This data further suggests the retrosplenial cortex is an important hub for distinguishing environmental context and highlights the diversity of functions for beta oscillations across the brain, which can be observed using high-density EEG.
Effects of chronic diseases on health related quality of life is mediated by sleep difficulty in middle aged and older adults
A noninvasive hyperkalemia monitoring system for dialysis patients based on a 1D-CNN model and single-lead ECG from wearable devices
Exogenous dopamine application ameliorates chilling injury and preserves quality of kiwifruit during cold storage
Airspace closures due to reentering space objects
Abstract Uncontrolled reentries of space objects create a collision risk with aircraft in flight. While the probability of a strike is low, the consequences could be catastrophic. Moreover, the risk is rising due to increases in both reentries and flights. In response, national authorities may choose to preemptively close airspace during reentry events; some have already done so. We determine the probability for a rocket body reentry within airspace over a range of air traffic densities. The highest-density regions, around major airports, have a 0.8% chance per year of being affected by an uncontrolled reentry. This rate rises to 26% for larger but still busy areas of airspace, such as that found in the northeastern United States, northern Europe, or around major cities in the Asia-Pacific region. For a given reentry, the collision risk in the underlying airspace increases with the air traffic density. However, the economic consequences of flight delays also increase should that airspace be closed. This situation puts national authorities in a dilemma—to close airspace or not—with safety and economic implications either way. The collision risk could be mitigated if controlled reentries into the ocean were required for all missions. However, over 2300 rocket bodies are already in orbit and will eventually reenter in an uncontrolled manner. Airspace authorities will face the challenge of uncontrolled reentries for decades to come.