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Atomistic Origin of Microsecond Carrier Lifetimes at Perovskite Grain Boundaries: Machine Learning-Assisted Nonadiabatic Molecular Dynamics

Natural killer cells are decreased in systemic sclerosis and have diagnostic value for pulmonary arterial hypertension incorporation

Molecular Uranium Dioxide-Mediated CO₂ Photoreduction

Web tension field action of a stainless steel section with stiffened web and folded flanges under bending and shear interaction

Electrochemically Driven Selective Olefin Epoxidation by Cobalt–TAML Catalyst

Author Correction: Mirror-invariance is not exclusively visual but extends to touch

Pressure-Induced Engineering of Surface Oxygen Vacancies on Metal Oxides for Heterogeneous Photocatalysis

Author Correction: Tunable optical and photovoltaic performance in PTB7-based coloured semi-transparent organic solar cells integrated MgF2/WO3 1D-photonic crystals via advanced light management

Dual Pathways of Photorelease Carbon Monoxide via Photosensitization for Tumor Treatment

Calculation algorithm of additional stresses in irregularly shaped foundation soils under non-uniform loading

Author Correction: Prediction of prognosis in patients with cerebral contusions based on machine learning

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Transient Triplet Metallopnictinidenes M–Pn (M = Pd^II, Pt^II; Pn = P, As, Sb): Characterization and Dimerization

Life cycle assessment of a luxury fashion brand’s HPP event booth in the context of circular economy

Surface Copassivation Strategy for Developing Water-Soluble InP Colloidal Quantum Dots with High Luminescence and Suppressed Blinking

Influences of aqua-(2-formylbenzoato) triphenyltin(IV) on regression of hypoxic solid tumor through mitochondrial mediated pathway by inhibiting Hif-1 alpha

Facile, Reversible Hydrogen Activation by Low-Coordinate Magnesium Oxide Complexes

Identification of salt-resilient cotton genotypes using integrated morpho-physiological and biochemical markers at the seedling stage

Selective Depolymerization for Sculpting Polymethacrylate Molecular Weight Distributions

UPLC-qTOF-MS/MS profiling of phenolic compounds in Fagonia arabica L. and evaluation of their cholinesterase inhibition potential through in-vitro and in-silico approaches

Abstract Fagonia arabica L. is a widely used traditional medicinal herb. This study explored the flavonoid and phenolic acid content in the aerial parts of F. arabica, leading to the tentative identification of 42 compounds using Ultra-Performance Liquid Chromatography-Quadrupole Time-of-Flight Mass/Mass Spectrometry and analyzed with the phytochemical-focused RIKEN tandem mass spectral database (ReSpect) for identification based on authentic standards. The total phenolic and flavonoid content was measured in the ethyl acetate and butanol fractions. The flavonoid content in the ethyl acetate fraction was 101 ± 1.43 µg Rutin/mg, compared to 6.48 ± 0.29 µg rutin/mg in the butanol fraction. Similarly, the ethyl acetate fraction contained 199.14 ± 1.58 µg gallic acid/mg, while the butanol fraction had 47.69 ± 0.54 µg gallic acid/mg. Also, the study demonstrated the effectiveness of the different fractions of Fagonia arabica L. in inhibiting the butyrylcholinesterase enzyme, which is a key contributor to the progression of Alzheimer’s disease. At a concentration of 0.45 mg/mL, the ethyl acetate fraction showed the highest efficiency, inhibiting butyrylcholinesterase by 50% (IC50). Based on the in vitro results, a molecular docking study suggested the selectivity of the tentatively identified compounds towards butyrylcholinesterase over acetylcholinesterase, as kaempferol-3-O-glucoside achieved the highest selectivity. This insight could inform potential modifications to enhance selectivity, which may be applied in the synthesis, semi-synthesis, and development of novel treatments for Alzheimer’s disease.