Browse Articles

Functional analysis of amino acid substitutions within human AGT1 in a cell-based platform to support the diagnosis of primary hyperoxaluria type 1

Journal of Biological Chemistry Leonardo Gatticchi, Ilaria Bellezza, Gill Rumsby et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110494

Systematic characterization of zinc in a series of breast cancer cell lines reveals significant changes in zinc homeostasis

Journal of Biological Chemistry Mena Woyciehowsky, Portia Larson, Annika R. Stephan et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110442

Maintenance of proper phosphatidylinositol-4-phosphate level by Stt4 and Sac1 contributes to vesicular transport to and from the plasma membrane

Journal of Biological Chemistry Tomoki Sano, Makoto Nagano, Hiroki Shimamura et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110410

PTH stimulation of Rankl transcription is regulated by SIK2 and 3 and mediated by CRTC2 and 3 through action of protein phosphatases 1, 2, 4, and 5

Journal of Biological Chemistry Michael J. Mosca, Zhiming He, Nagarajan Selvamurugan et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110434

Application of NanoSIMS and isotopic labeling to analyze the spatial distribution of the plant iron chelator nicotianamine

Journal of Biological Chemistry Tomoko Nozoye, Miyuki Takeuchi, Fabian Hollmann et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110478

The GTPase κB-Ras is an essential subunit of the RalGAP tumor suppressor complex

Journal of Biological Chemistry René Rasche, Lisa Helene Apken, Sonja Titze et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110460

Understanding the substrate recognition and catalytic mechanism of 2-O-methyl fucosidases from glycoside hydrolase family 139

Journal of Biological Chemistry Zak McIver, Alicia Moraleda-Montoya, Zongjia Chen et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110407

Genetic variants linked to neurodevelopmental disorders within the β3-β4 loop of the TRIO PH2 domain release autoinhibition of GEF2 activity

Journal of Biological Chemistry Melissa G. Carrizales, Andrew D. Boulton, Anthony J. Koleske Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110429

Proximity labeling techniques for protein–protein interaction mapping in plants

Journal of Biological Chemistry Beyza Özmen, Leonard Blaschek, Michael Ogden et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110501

Identification of SRSF9 through pooled shRNA screening links BNIP3 splicing to autophagy and metabolic reprogramming in breast cancer

Journal of Biological Chemistry Anchala Pandey, B. Jithin, Srinivas Abhishek Mutnuru et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110482

Structural biology of Parkinson’s disease-associated leucine-rich repeat kinase 2 (LRRK2)

Journal of Biological Chemistry Andres E. Leschziner Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110376

Two stages of substrate discrimination dictate selectivity in the Escherichia coli MetNI-Q ABC transporter system

Journal of Biological Chemistry Janet G. Yang, Hulda Yuchun Chen, John H. Guardado et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110493

The metastasis-associated protein MTA3 promotes cardiac repair by inhibiting the fibroblast to myofibroblast transition during fibrosis

Journal of Biological Chemistry Xu Wang, Yihui Liu, Heng Liu et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110448

Hemoglobin β-F41K: A recombinant oxygen carrier prototype engineered for enhanced heme retention, stability, and optimal oxygenation properties

Journal of Biological Chemistry Mohd Asim Khan, Kajal Yadav, Anthony V. Signore et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110477

Regulatory mechanism of the SenX3-RegX3 two-component system in Mycobacterium smegmatis: Roles of PhoU in sensing inorganic phosphate levels

Journal of Biological Chemistry Youjin Seung, Ha-Eun Baik, Eun-Jin Park et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110435

The redox landscape of pyruvate:ferredoxin oxidoreductases reveals often conserved Fe–S cluster potentials

Journal of Biological Chemistry Sheila C. Bonitatibus, Ryan V. Pham, Andrew C. Weitz et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110380

TFAP2C drives cisplatin resistance in bladder cancer by upregulating YAP and activating β-catenin signaling

Journal of Biological Chemistry Qiufeng Pan, Changmin Zou, Zhigen Lin et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110387

Hypoxia promotes the generation of a versican-rich extracellular matrix by human coronary artery endothelial cells

Journal of Biological Chemistry Sara M. Jørgensen, Song Huang, Lasse G. Lorentzen et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110459

Molecular arrangements that accompany binding of rice xylanase inhibitor protein OsXIP and the Rhizopus oryzae GH11 xylanase RXyn2

Journal of Biological Chemistry Takayuki Ohnuma, Jun Tanaka, Harutada Ozaki et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110385

Neuronal endolysosomal alterations induced by Apolipoprotein E4 emerge over time in primary neurons

Journal of Biological Chemistry Emma Nyberg, Sabine C. Konings, Nils Lindblom et al. Aug 01, 2025 DOI: 10.1016/j.jbc.2025.110479