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Impact of government’s dual-carbon attention on urban carbon emissions reduction: evidence from the Yangtze River Delta
Abstract There is an ever-increasing concern among local governments in China regarding the relationship between government attention and carbon emissions. This study proposes a new dual-carbon attention dictionary and measures local governments’ dual-carbon attention (GCA) level using textual analysis and the maximum reverse matching method. Our research highlights that an extended STIRPAT model exhibits the significance of local governments’ efforts in achieving CO 2 emissions reduction. Empirical evidences demonstrate that increased GCA leads to a greater reduction in urban CO 2 emissions. Furthermore, GCA greatly decreases urban CO 2 emissions in the Yangtze River Delta (YRD) via accelerating the upgrading of industrial structures and improving emission-reduction policies implementation and reducing carbon emissions intensity. Additionally, the GCA has stronger robustness in decreasing urban CO 2 emissions in the YRD under peers GCA, environmental governance policies and environmental protection investment.
Impact and resiliency of the early phase of the COVID-19 pandemic on healthcare providers and their household members
BRD4 and MYB inhibition overcomes venetoclax resistance in EVI1-rearranged acute myeloid leukemia
Evaluation of heat transfer performance of a heat exchanger tube mounted with an I-rib twisted tape and twisted winglets
Gradient transformer Self-Attention U-Net for enhanced crack detection in concrete bridges
Impact of BaO on the gamma-ray shielding performance of lanthanum barium-borate glasses
Abstract This study examined the gamma radiation shielding properties of test barium-lanthanum borate glasses having the composition (80 − x) B 2 O 3 –8TiO 2 –11ZnO–x BaO–1La 2 O 3 (x = 26, 29, 32, and 35 mol%). The glasses are designated as Ba26La1, Ba29La1, Ba32La1, and Ba35La1, and were prepared from the melt-quenching method. The radiation shielding parameters, mass attenuation coefficient (MAC), linear attenuation coefficient (LAC), half-value layer (HVL), tenth-value layer (TVL), mean free path (MFP), and effective atomic number (Z eff ), were evaluated by using Phy-X/PSD software, at energy (0.015–15 MeV). The results of this study indicate that an increased amount of BaO in the glasses improves the attenuation property of the glasses. For example, Ba35La1 had the highest LAC value of 186.392 cm −1 at 0.015 MeV. This suggests that the Ba35La1 glass has very good absorption for low energy gamma rays. Ba35La1 exceeds many lead-free shielding materials and achieves a comparable attenuation value to lead-based shielding glasses values with respect to attenuation coefficients for specific lead-based glasses, with energies relevant to diagnostic photons. Ba35La1 is a great lead-free candidate for medical and industrial radiation shielding applications. Some properties of the shielding characteristics in Ba35La1 strengthened this claim such as, the greatest shielding efficiency over the total energy spectrum was manifested by Ba35La1 < 0.1 MeV due to the photoelectric region, coupled with the K-edge discontinuity at 0.037 MeV as a result of the Ba absorption edge; thus confirming the role high-Z modifiers had in enhancing the attenuation coefficient results within the region of interest.
Cold plunge: how I gained hands-on experience in marine biology
Uniplanar aquatic exercise quantified with inertial sensors and pose estimation
Abstract This study presents a concurrent validity analysis of two measurement techniques for quantifying uniplanar human movement during aquatic exercise. Established marker-based biomechanical motion capture systems are labour intensive, and command significant prices, limiting their accessibility in non-specialist environments. Therefore, this study assesses the applicability of alternate measurement methods; inertial measurement unit (IMU) sensors and markerless computer vision (CV) tracking in the form of pose estimation , applied to the quantification and analysis of aquatic exercise. This analysis establishes the validity of each method by deriving several performance-related metrics; range of motion, duration, and angular velocity, of uniplanar aquatic exercise repetitions. Using the proposed methods it was observed that each performance metric demonstrated excellent agreement (ICC $$\ge$$ 0.94) across methods, based on intraclass correlation coefficients in 20 healthy young adults (n = 9 women, aged 20-26). This analysis encompassed two exercise types, knee flexion-extension and hip flexion-extension. The authors highlight that this contribution represents a step toward establishing robust, accessible methods for objective exercise quantification in aquatic settings, where previously there has been an absence of convenient technical solutions.
Diagnostic and prognostic biomarkers associated with histotype in advanced epithelial ovarian cancer
Abstract Despite advances in cancer treatments, epithelial ovarian cancer (EOC) remains the leading cause of death among gynecologic cancers. EOC is stratified into five main histopathological subtypes: high-grade serous carcinoma (HGSC), low-grade serous carcinoma (LGSC), endometrioid carcinoma (EC), clear cell carcinoma (CCC), and mucinous carcinoma (MC). However, personalized treatment strategies and reliable biomarkers for all histotypes remain elusive. Building on our previous work with early-stage EOC, we aim to explore diagnostic and prognostic biomarkers in advanced-stage EOC, updated to the latest World Health Organization classification guidelines from 2020, using comprehensive transcriptomic profiling from total RNA sequencing of 146 EOCs. Differential expression analysis identified top 9 histotype-specific gene panels for HGSC, CCC, MC, and EC, including S100A1 (HGSC), ARID3A (CCC), LGALS4 (MC), and PAX9 (EC). We also identified gene candidates associated with overall survival and disease-specific survival, reflecting both favorable (e.g., OTOF , EEF1E1-BLOC1S5 , and STAC3 ) and unfavorable (e.g., SMOC1 , GDPGP1 , EPRS1 ) clinical outcome. Additionally, enrichment analysis revealed tumor progression-related pathways unique to each histotype, offering insights into the molecular mechanisms underlying disease progression and potential therapeutic targets. These findings provide valuable insights into the molecular landscape of advanced-stage EOC, paving the way for more effective diagnostic and prognostic tools across diverse histotypes.