Browse Articles

Prevalence and risk factors for major arterial bleeding in fragility pelvic fractures in the aging population

Abstract Fragility pelvic fractures (FPF) are increasingly common among elderly patients and, despite being caused by low-energy mechanisms, can result in major arterial bleeding (MAB). However, few studies have examined the prevalence and predictors of MAB in this population. This study aimed to evaluate prevalence and potential risk factors associated with MAB in elderly patients with FPF. This retrospective cohort study used data from the Japan Trauma Data Bank. The study included patients (age ≧ 65 years) with FPF between 2010 and 2021, defining FPF as pelvic fractures caused by a ground-level fall. Demographic, comorbidities, and antithrombotic use were analyzed. MAB was operationally defined by the performance of therapeutic angioembolization (TAE). Multivariable logistic regression was performed to identify predictors of MAB and in-hospital mortality. A total of 1,354 patients met inclusion criteria; 80 patients (5.9%) underwent TAE. Compared with the non-MAB group, the MAB group had significantly higher rates of liver disease, cerebral vascular disease, use of antithrombotic agents, systolic blood pressure (SBP) < 90 mmHg, and lower Glasgow Coma Scale scores. A multivariable logistic regression analysis revealed that age (OR 1.04, 95% CI 1.01–1.07), male sex (OR 2.42, 95% CI 1.49–3.93), cerebral vascular disease (OR 2.11, 95% CI 1.21–3.67), liver disease (OR 6.23, 95% CI 2.36–16.40), and SBP < 90 mmHg (OR 5.43, 95% CI 2.96–9.97) were independently associated with MAB. MAB itself was independently associated with higher in-hospital mortality (OR 4.3, 95% CI 2.1–8.9). Notably, 28% of in-hospital deaths occurred within 48 h and 50% within 7 days of admission. Despite their low-energy origin, FPFs can lead to life-threatening hemorrhage requiring invasive hemostatic intervention. A subset of elderly patients—particularly those with comorbidities or hypotension upon admission—are at elevated risk of MAB and poor outcomes. Early recognition and targeted intervention strategies are essential to improve survival in this growing and vulnerable population.

Theorization regarding access to oral health care for Brazilian prisoners: A qualitative study

The Brazilian prison system has faced difficulties in guaranteeing the fundamental rights of the population deprived of liberty, including access to oral health. In view of this, the aim of our study was to formulate a theory concerning access to oral health and the influencing factors, grounded in the perspectives of incarcerated men. We carried out a qualitative study with men deprived of liberty, who were serving their sentences in a closed regime in a state prison unit in Minas Gerais (Brazil). The data collection was conducted through semi-structured interviews and processed utilizing Grounded Theory. The categories produced in this qualitative analysis using Grounded Theory were interpreted and organized based on the Patient-Centered Access Conceptual Framework. We conducted interviews with 16 men, and analysis allowed the creation and bringing closer together of the following categories related to the patient: 1) Ability to perceive 2) Ability to seek 3) Ability to reach 4) Ability to pay 5) Ability to engage, and dimensions related to the service offered: 1) Approachability 2) Acceptability 3) Availability and accommodation 4) Affordability 5) Appropriateness. For men deprived of liberty, barriers to accessing oral health result from state negligence, which promotes overcrowding and a lack of qualified professionals. This scenario creates a micropolitics of access, breaking the logic of equity.

Effect of water application on ammonia emissions from simulated beef cattle feedyard surfaces

Leaders in the global banking network: Analysis of the Bank for International Settlements network data

Prior work on networks derived from the Bank for International Settlements (or BIS) focused on centrality measures such as degree, betweenness, and DebtRank, with less attention given to adversarial network models. In this work, we address this gap by introducing an adversarial network-based method to locate influential countries within the global banking network. We analyze BIS data from 2000 to 2015, modeling countries as nodes and lending relationships as weighted, directed edges. We study low-key leaders, which are countries with outsize influence despite lower centrality, and highly exposed nodes, which are countries most vulnerable to defaults. Using the Common Out-neighbor (or CON) score with PageRank, we quantify each country’s influence and exposure, and define a measure of low-key leader strength. Our results show that low-key leaders, such as those in the United States and Mexico, possess strong influence with lower exposure to contagion, whereas highly exposed leaders, like those in Germany and the United Kingdom after 2003, maintain broad lending portfolios that heighten vulnerability. We also examine these roles over time, including the United States’ loss of low-key leader status after the 2008 financial crisis. Our analysis of low-key leaders and highly-exposed nodes provides new insights into systemic risk within the BIS network.

Naringenin restores osteogenic differentiation in TNF-α-Treated bone marrow mesenchymal stem cells by targeting AKR1B1

Abstract In chronic inflammatory microenvironments, TNF-α disrupts bone remodeling by suppressing osteogenic differentiation in human bone marrow mesenchymal stem cells (hBMSCs), while conventional TNF-α inhibitors lack osteoprotective effects. This study reveals that naringenin counteracts TNF-α-induced osteogenic suppression by potentially targeting AKR1B1 to restore redox balance and inhibit NF-κB-mediated inflammation. In vitro experiments demonstrated that naringenin restored osteogenic capacity in TNF-α-treated hBMSCs, enhancing ALP activity, mineralization, and expression of RUNX2/OCN while reducing IL-6/IL-1β levels. Mechanistically, naringenin scavenged free radicals, elevated SOD/CAT activity, and attenuated TNF-α-driven ROS accumulation. Bioinformatics analysis identified TNF-α-activated NF-κB signaling and upregulation of the oxidative stress enzyme AKR1B1, with molecular docking confirming strong binding between naringenin and AKR1B1. This study pioneers AKR1B1 as a novel therapeutic target for inflammatory bone loss, demonstrating naringenin’s synergistic “antioxidant-anti-inflammatory-pro-osteogenic” effects. These findings provide a theoretical foundation for phytochemical applications in orthopedic therapies and highlight potential clinical translation strategies.

Delineation in fuzzy boundaries: Canonical ordination analysis discriminates between cryptic species by linking taxonomy to genetics, morphology, climate, and space

In species complexes, delineation of cryptic species remains a major challenge due to their morphological similarities despite significant genetic divergence. The related problems of defining and recognizing hidden diversity impact a range of sciences, posing theoretical and practical problems. Our article introduces a novel application of canonical ordination analysis as a powerful tool for examining and testing the interplay between genetic and morphological variability in cryptic species while accounting for their relation to climate and spatial descriptors, aiming to discriminate them by integrating multiple sources of predictors. We used data on 60 Fruticicola sp. populations across its range, belonging to three cryptic species— Fruticicola fruticum , F. similis , and F. gemina . We used five variable categories: taxonomy (response variables), genetics and morphology (response variables and predictors), climate and space (predictors). We applied distance-based redundancy analysis and canonical correspondence analysis to examine and test relationships among these variable categories, variation partitioning procedure to disentangle the effects of the considered predictors, and linear discriminant analysis to test their discriminatory power. Morphology was best explained by climate (mainly humidity), whereas genetic distances showed patterns shared between climate and space. Because the three pseudocryptic species were defined on molecular basis, taxonomy was almost completely explained by genetic distances. Although, when considered alone, morphology, climate, and space did not perform well in discriminating the species, when included together in the models, they were able to correctly classify the samples. We demonstrate how this multivariate canonical approach enhances species delimitation, offering a clearer understanding of cryptic diversity and its ecological implications. By linking these facets, we provide a comprehensive framework that connects taxonomic classifications with ecological and evolutionary processes. Hence, our results bring more insight into the processes linked to hidden diversity while providing new tools for its assessment, broadening the framework for applied research.

DEX in near Earth orbit in light of Venus Orbiter Dust Experiment

From sea to cure: Discovery of marine-derived therapeutics against Fusarium solani in shrimps for enhancing aquaculture sustainability

Fusarium solani , an Ascomycota filamentous fungus species, causes shell disease or mycotic infections in wild and farmed shrimps. It causes black gill disease in shrimps, which has no specific treatments, so cutting-edge pharmaceutical research to prevent glutamine synthetase is needed to stop it and reduce its negative effects on aquaculture productivity and health. In silico drug design has been evaluated as an innovative treatment for black gill disease in shrimps caused by F. solani . Initially, molecular docking targeted the Glutamine synthetase (AF-Q9UUN6-F1-v4), utilising a set of 1,191 seaweed metabolites found in the Seaweed metabolite database (SWMD). The three lead compounds, CID: 359 (Phloroglucinol), 11640528 ((6E,10E,14E)-16-(2,5-dihydroxy-3-methylphenyl)-2-hydroxy-2,6,10,14-tetramethyl hexadeca-6,10,14-trien-3-one), and 8768 (Protocatechualdehyde), have binding affinities of −5.752, −5.374, and −5.102 kcal/mol, with negative binding free energies of −16.27, −48.99, and −27.48 kcal/mol, respectively. Additionally, they have excellent ADMET properties, making them safe and effective, whereas HOMO-LUMO and QSAR studies suggest thermodynamic stability and biological activity, notably antifungal efficacy. The compounds were subsequently assessed to verify their durability and binding affinity to the target protein by conducting an MD simulation analysis. In the MD simulation, the ligands evaluated in this study exhibited notable robustness of the proteins’ binding site when complexed with CID: 8768, which suggests a strong interaction between the target and lead compound. Consequently, the compound obtained from the seaweed Polysiphonia lanosa may inhibit the fungal activity of F. solani glutamine synthetase protein, revealing that the compound might be an effective novel therapeutic candidate.

Design of a single particle-interferometric reflectance imaging sensor adipo-chip for obesity biomarker screening

Comparison of the effectiveness and safety of vaginal and sublingual low-dose misoprostol versus vaginal dinoprostone for labor ınduction: A retrospective cohort study

Background Labor induction is one of the most common obstetric interventions, yet the optimal pharmacological agent and route of administration remain subjects of ongoing debate. Prostaglandin analogs such as misoprostol and dinoprostone are widely used for cervical ripening and induction; however, evidence comparing their effectiveness and safety across different routes is still limited. Aim The primary purpose of the study is to evaluate the efficacy and safety of vaginal and sublingual misoprostol and vaginal dinoprostone pessary in labor induction. Materials and Methods Patients were divided into three groups based on the labor induction methods used. The first group included patients who received 25 µg vaginal misoprostol for labor induction, the second group included patients who received 25 µg sublingual misoprostol, and the third group included patients who received vaginal dinoprostone pessary. The primary outcome of the study was to evaluate vaginal delivery rates and time from induction to delivery of the fetus. The secondary outcomes of the study were to evaluate cesarean delivery rates, indications for cesarean delivery, first- and fifth-minute Apgar scores, birth weight, gender, amniotic fluid meconium contamination, and admission rates to the neonatal intensive care unit (NICU). The study data were collected from the hospital’s automation system and archives. All patients’ demographic and obstetric characteristics and maternal and fetal outcomes were recorded in a spreadsheet document (Microsoft Excel™), and statistical analyses were performed using the SPSS 28.0 program. Results Vaginal delivery rates were higher in the group where vaginal (86,5%) and sublingual misoprostol (85,3%) were applied, and cesarean delivery rates were higher in the group where vaginal dinoprostone pessary (31,6%) was applied (p = 0.000). When the groups were compared according to the duration of labor, no difference was found in the vaginal (523.86 ± 405,92) and sublingual misoprostol (560.15 ± 438,00) groups, while the duration of labor was significantly higher in the dinoprostone pessary group (857.37 ± 558,36) (p = 0.000). Hyperstimulation (6.8%) (p = 0.007) and admission rates to the neonatal intensive care unit (9.1%) (p = 0.004) were higher in the dinoprostone group, and this difference was statistically significant. Conclusion According to the results of the study, low-dose vaginal or sublingual misoprostol was found to be more effective and safer than vaginal dinoprostone pessary in labor induction.

The origin and influence of non-cavity modes in a micropillar Bragg microcavity

Abstract Controlling the photonic environment of emitters is essential to the design of classical and quantum light sources. We study the case of a dipole-like emitter in a cylindrical pillar etched into a planar Bragg microcavity, which is a common design of quantum-dot single photon source. In addition to the well-known cavity modes created by the high-reflectivity of the Bragg mirrors at small in-plane wavevectors, we show the presence of broad spectral features that play a key role in controlling photon collection efficiency and Purcell enhancement. These ‘non-cavity’ modes are insensitive to the periodic index modulation of the Bragg reflectors, but arise from the cylindrical pillar geometry, as we show by comparison with simulations of uniform pillars, which reproduce the non-cavity modes. This approach provides a tool for understanding and modelling these often-disregarded decay channels as a function of source height, cavity dimensions and surface layers.

Global assessment of pain care quality for musculoskeletal disorders: Insights from the quality of care index (QCI) from 1990 to 2021

Background Musculoskeletal disorders (MSDs) represent a global primary cause of disability, affecting over 1.69 billion individuals and accounting for over 160 million disability-adjusted life years (DALYs) in 2021. Conventional metrics assess care quality inadequately, necessitating a multidimensional evaluation framework. Thus, this study introduces a novel metric — the Quality of Care Index (QCI) — to comprehensively evaluate the MSD landscape. Objective To develop a novel QCI for MSDs and evaluate global trends, disparities, and drivers from 1990 to 2021. Methods Using Global Burden of Disease (GBD) 2021 data across 204 countries, we constructed a composite QCI integrating four domains: Pain Relief Rate(PRR), Opioid Use Rate(OUR), Need-Independent Coverage(NIC), and Patient Satisfaction(PS). These were standardized into a single index using Principal Component Analysis (PCA). Trends were analyzed via Estimated Annual Percentage Change (EAPC), with disparities assessed by Socio-Demographic Index (SDI) and geography. Results Significant increases in MSDs prevalence (over 12.7% of low back pain; near doubling of osteoarthritis) and DALYs occurred globally, driven by aging populations. Geographic Paradox: Lower- and middle-income countries (LMICs; e.g., Vanuatu, Nicaragua, Central African Republic) achieved higher QCI scores than high-income nations (e.g., Italy, Germany, Japan). QCI improved in LMICs (notably for osteoarthritis/neck pain) but stagnated or even declined in high-income regions. DALYs correlated positively with SDI (R = 0.649–0.863; p < 0.001), with steepest rises in middle- and high-SDI areas for low back pain and osteoarthritis. Conclusion The QCI scores reveal critical relationship between MSDs burden and care quality. High-income regions experience challenges of opioid overuse and stagnant patient satisfaction, while LMICs express gains in access and perceived relief. Implementing context-stratified strategies — de-implementing low-value care in high-SDI areas while scaling evidence-based access in resource-constrained regions — constitutes a critical pathway to equitably alleviate the global MSDs burden.

Symmetric bug prediction in software requirement by machine learning algorithms

Optimizing and forecasting the development of China’s sports industry structure

The sports industry’s contribution to economic growth is increasingly pronounced, as structural optimization offers significant potential to enhance its impact on economic development. This study employs the grey relational analysis and GM (1,1) grey prediction models to examine the correlation between China’s sports sub-sectors and key national economic development indicators, providing projections for future trends. Results indicate that the sports manufacturing sector and related product sales demonstrate the strongest correlation with Gross Domestic Product (GDP), highlighting their critical role in fostering economic growth. The GM (1,1) model reliably forecasts future trends in the sports industry’s added value. Based on these insights, sector-specific recommendations are proposed to promote structural optimization and sustainable development in China’s sports industry.

Multi-omic analysis reveals elevated BRI3BP expression associated with hepatocellular carcinoma progression and poor prognosis

Abstract BRI3BP, an RNA-binding protein upregulated in multiple cancers, plays an undefined role in hepatocellular carcinoma (HCC). This study investigates its diagnostic and prognostic potential in HCC. Multi-omics analysis of TCGA and GEO data identified BRI3BP-interacting genes and enriched pathways. Genomic and epigenetic alterations were assessed using cBioPortal and MethSurv. Immune infiltration was profiled via ssGSEA and TIMER 2.0. Prognostic relevance was validated through survival analysis, Cox regression, and experimental assays. BRI3BP was overexpressed in HCC and correlated with advanced tumor stage, shorter overall survival (OS), and disease-free survival (DFS). Functional enrichment linked BRI3BP to cell cycle regulation, Rho GTPase activity, and copper homeostasis. Analysis of transcriptomic data revealed that BRI3BP expression also significantly correlated with immune cell infiltration and an immunosuppressive microenvironment, validated by immunohistochemistry showing reduced CD8 + and increased CD68 + cells in high-BRI3BP samples. In vitro, BRI3BP overexpression promoted HCC cell migration and invasion and activated the ROCK signaling pathway, suggesting potential involvement in tumor progression. Drug sensitivity assays confirmed lower lapatinib IC50 in overexpression models. High BRI3BP expression correlates with aggressive HCC phenotypes, poorer survival, and dysregulated oncogenic pathways, supporting its role as a prognostic biomarker and candidate therapeutic target.

How do healthcare professionals on non-palliative care wards perceive quality of care in the dying phase? Personal and organizational predictors identified in a cross-sectional study

Background Most people in European countries die in hospitals outside of specialist palliative care wards. Healthcare professionals of all disciplines are therefore often involved in the care for dying patients. Healthcare professionals’ perception of quality of care in the dying phase as well as its predictors are of interest to improve quality of care on non-palliative care hospital wards. Aim Identification of personal and organizational predictors of healthcare professionals’ perceived quality of care in the dying phase. Methods Cross-sectional online survey with healthcare professionals of ten non-palliative care hospital wards of two university medical centers. Descriptive statistics were used to describe the data. A hierarchical linear regression model with ten theoretically derived personal (gender, age, profession, palliative care training, spirituality, two self-care items, general self-efficacy, thanatophobia, burden factors when caring for dying patients) and two organizational predictors (type of ward, interprofessional patient-centered teamwork) was developed. The dependent variable was an eleven-point Likert-scaled item (0 = extremely bad, 10 = ideal) measuring the quality of care in the dying phase at the respective ward, perceived by healthcare professionals. Predictors were categorized as modifiable and non-modifiable. Results Most of the n = 201 participants were female (64.7%), nurses (57.2%) and 30–50 years old (53.2%). The regression model was statistically significant (p < 0.001) and explained 30.7% of the total variance. Lower perceived quality of care in the dying phase was associated with younger age (β = 0.15, ρ = 0.020), being a nurse (β = 0.29, ρ < 0.001), and lower perception of interprofessional patient-centered teamwork on their ward (β = 0.37, ρ < 0.001). Discussion Perceived quality of interprofessional patient-centered teamwork was the most clinically relevant predictor in this model, as it had the strongest association and was modifiable. Age and profession were significant, non-modifiable predictors but can be considered when implementing interventions. As improving the perceived quality of care in the dying phase could be beneficial for dying patients, interventions strengthening interprofessional patient-centered teamwork should be implemented on non-palliative care hospital wards.

Study on the mechanical characteristics and anchorage performance of the anchor cable with precast internal-anchor-head (PIAC)

Abstract In order to improve the anchoring force of traditional anchor cables while ensuring low cost, this paper proposed a new-type anchor cable structure with a precast internal-anchor-head (PIAH) at the anchor cable end. The reliability of the new structure was thoroughly validated through theoretical analysis, indoor pull-out experiments, and numerical simulations. Firstly, the mechanical pattern based on the characteristics and anchoring mechanism of the PIAH structure was analyzed, and the calculation methods under different failure modes were proposed. Secondly, a full-scale physical model experiment was conducted to study the effects of varying lengths PIAH on the tensile stress of the grout, stress distribution between grouting sections and the surrounding rock, shear stress distribution between PIAH and grout, and the yield conditions of the PIAH. Results show that after applying the PIAH, the ultimate bearing capacity increases from 796.4 to 921.2 kN, and the ultimate strain decreases from -1219.7 × 10 –6 to -309.5 × 10 –6 , a reduction of 74.63%. It indicates that the strain state of the grout will be substantially improved after setting the PIAH in anchor cable, and the bond strength between the grout and the hole wall could be enhanced, result in effective increase of anchoring force. At the same time, longer PIAH are more favorable for controlling cable deformation. Furthermore, to further validate the experimental results, numerical models of multiple-types anchor cable structures were established based on finite difference numerical method. Simulation results show that, under the same conditions, the ultimate bearing force of the anchor cable increases as the length of PIAH increases, and the overall elastic modulus of the anchoring system could also be improved. Compared to the grout of the Traditional Prestressed Anchor Cable (TPAC), the concentration degree of axial stress of Anchor Cable with Precast Internal-anchor-head (PIAC) was only 28.57%, effectively reduced the degree of stress concentration. Additionally, the maximum effective length of PIAH is about 1.5 ~ 2 m under the test conditions of a 4 m PIAC and further length increases produce diminishing returns. Meanwhile, PIAC can be used not only in hard rock formations, but also in soft rock formations if improving the strength of the interface between the surrounding rock and the grout. The research results have valuable reference significance for the engineering application of PIAC.

Genomic characteristics of Lacticaseibacillus rhamnosus strains isolated from blood

Lacticaseibacillus rhamnosus is widely recognized for its health-promoting properties, which have led to its broad application in the production of food and dietary supplements. Nevertheless, although rare and typically limited to patients with underlying conditions, adverse effects have also been reported. In this study, we sequenced and characterized the genomes of seven L. rhamnosus strains isolated from blood. Using a hybrid approach that combined Illumina and Oxford Nanopore technologies, we obtained complete genomes ranging from 2.96 to 3.13 Mb, with a GC content of 46.7–46.8%. Comparative analyses with publicly available L. rhamnosus genomes revealed that these isolates were genetically related to strains from highly diverse origins, including plants, dairy products, dietary supplements, the gastrointestinal and genitourinary tracts, as well as blood and other clinical samples from geographically distant regions. Importantly, neither core genome multilocus sequence typing (cgMLST) nor prophage and CRISPR module analyses indicated similarity to the widely used probiotic strain L. rhamnosus GG. Gene-based analysis identified determinants associated with bacteriocin production, adhesion, health-promoting traits, and potential pathogenicity of the strains. Notably, several genes linked to probiotic functions also overlapped with virulence factors found in pathogenic microorganisms. These findings demonstrate the genomic diversity of L. rhamnosus blood isolates and highlight the dual role of certain genetic determinants, underlining the importance of careful strain-level evaluation when selecting L. rhamnosus strains for probiotic use.

Intelligent ship traffic supervision system based on distributed blockchain and federated reinforcement learning for collaborative decision optimization

Abstract This paper presents an innovative intelligent decision optimization model that integrates distributed blockchain technology with federated reinforcement learning to address critical challenges in ship traffic collaborative supervision. Traditional maritime traffic monitoring systems suffer from data silos, privacy concerns, and centralized decision-making bottlenecks that impede effective multi-jurisdictional coordination. The proposed framework employs a multi-layered architecture consisting of data layer, blockchain layer, federated learning layer, and decision layer to enable secure data sharing while preserving operational autonomy among maritime authorities. The distributed blockchain mechanism ensures data integrity and immutability through cryptographic protocols and smart contracts, while the federated reinforcement learning algorithm enables privacy-preserving collaborative model training without exposing sensitive commercial information. Experimental validation demonstrates superior performance with 93.6% decision accuracy, 520ms average response time, and 285 transactions per second throughput. Case studies involving emergency collision avoidance, abnormal behavior identification, and search-and-rescue coordination confirm the system’s practical effectiveness, achieving 40% reduction in incident response times and 60% enhancement in cross-agency collaboration efficiency. The research provides a robust foundation for next-generation maritime traffic management systems that require secure multi-party collaboration and intelligent decision optimization.

The effect of parental enhancing program with mobile application on parental stress and competence among Thai adolescent postpartum women: A quasi-experimental matched control design

Background Adolescent pregnancy constitutes a critical public health issue worldwide. Young mothers face substantial physical and psychological changes as they transition to motherhood, while limited knowledge, experience, and maturity may impair parenting and increase stress. The study aimed to evaluate the effects of the parental enhancing program with mobile application on parental stress and competence among Thai adolescent postpartum women. Methods A quasi-experimental study using a matched control design was conducted among sixty adolescent postpartum women, aged 15−19. Participants were sequentially allocated to an intervention group (n = 30) receiving a parental enhancing program with mobile application, and a control group (n = 30) receiving standard postpartum care. Adolescent postpartum women in the intervention group received two sessions from the parental enhancing program before discharge with weekly follow-up through the Line Official Account™. Data were collected using questionnaires, including the Edinburgh Postnatal Depression Scale (EPDS), Parenting Stress Index (PSI-4-SF), and Parenting Sense of Competence Scale (PSOC). Evaluations were conducted during the 6-week postpartum. ANCOVA was used to compare post-intervention mean scores of parental stress and competence between groups. Results All enrolled participants completed the study (Intervention: 30; Control: 30). At 6-weeks postpartum, after controlling baseline EPDS scores, the results revealed that adolescent postpartum women in the intervention group demonstrated significantly lower parental stress (F(1,57) = 14.40, partial η² = 0.20, 95% CI [−14.05, −4.34], p < .001) and higher parental competence (F(1,57) = 8.79, partial η² = 0.13, 95% CI [1.90, 9.80], p < .01) compared to the control group. Conclusion The parental enhancing program with mobile application demonstrates promise for evidence of reducing parental stress and improving parental competence in postpartum adolescent mothers. However, further studies in randomized controlled trials are warranted to confirm its effectiveness and generalizability. Trial registration Thai clinical trials registry (TCTR20250309010).