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Bayesian-optimized machine learning and experimental study of Al₂O₃-CuO hybrid nanofluid thermal performance in turbulent circular tube flow

Scientific Reports Praveen Kumar Kanti, H. B. Marulasiddeshi, Nejla Mahjoub Said et al. Nov 05, 2025 DOI: 10.1038/s41598-025-23785-3

Abstract This study explores the thermal behavior of hybrid nanofluids (HNFs) composed of water mixed with equal proportions (50:50) of Al₂O₃ and CuO nanoparticles (NPs) under turbulent flow regimes. The nanofluids (NFs) are prepared in the volume concentrations range of 0–1%. Both experimental investigations and numerical simulations were carried out to evaluate the effects of NP concentration and Reynolds number (Re) on Nusselt number (Nu), friction factor, and entropy generation. Results demonstrated a marked enhancement in heat transfer with increasing NP concentration and flow rate. Notably, the use of HNFs led to a 71% reduction in total entropy generation (TEG) compared to water alone. Empirical correlations were developed to predict the Nu and friction factor accurately. Furthermore, an XGBoost machine learning model was employed to estimate thermal parameters with high precision. The model achieved an R² of 1.000 (training) and 0.991 (testing) with an MSE of 0.001 for TEG. For the friction factor, R² training as 0.686 and R² test as 0.916 (testing) were obtained. Nu model achieved perfect training accuracy (R² = 1.000) and strong testing performance (R² = 0.975, MSE = 29.457). These results affirm the effectiveness of XGBoost in modeling thermofluidic behavior in HNF systems.

Transition-Metal-Free Site-Selective β- and γ-C–H Borylation of Aliphatic Amines

Journal of the American Chemical Society Sumon Sarkar, Nitish Kumar Deo, Tong Zhang et al. Nov 05, 2025 DOI: 10.1021/jacs.5c12618

A 1.2-V 7.76-ENOB 1-MS/s single-ended SAR ADC in 65-nm CMOS for biomedical applications

Scientific Reports Kawther I. Arafa, Dina M. Ellaithy, Heba Shawkey et al. Nov 05, 2025 DOI: 10.1038/s41598-025-21817-6

Abstract A successive approximation register analog-to-digital converter (SAR ADC) is a promising approach used in biomedical applications due to its energy-efficiency architecture with less complex hardware implementation. The core building blocks of SAR ADC are sample-and-hold switch (S/H), comparator, logic control register, and digital-to-analog converter (DAC). To enhance the overall performance, a high-isolation CMOS bootstrap S/H switch has been used. The SFDR of proposed ADC has increased by up to 2.2 dB. Also, we propose a double-tail single-ended dynamic latch comparator with extra pair PMOS transistors that save power by up to 7.5% as compared to the traditional double-tail dynamic comparator. Moreover, after adding these pair of transistors into conventional double tail dynamic comparator without any calibration cost, the SNDR has increased by more than 2 dB and 0.3bit improvement of ENOB. Furthermore, a synchronous modified SAR logic control register based on low-power D flip-flops (FFs) is proposed. A metal-isolator-metal capacitor (MIM) with a modified capacitance reduction configuration is used to improve the active area of the capacitive DAC (CDAC) compared to the conventional CDAC with 36.7% saving power. The proposed ADC has been implemented using a 65-nm TSMC CMOS process, 1.2 V supply voltage with a sampling rate of 1 MS/s. An active area of 0.00585 mm 2 with a total post-result power consumption of 5.75 µW has been accomplished for the proposed fully integrated ADC.

Ultrafast Encapsulation of Bimetallic Nanoclusters into Zeolites: Linking Structural Features to Catalytic Performance

Journal of the American Chemical Society Tao Yu, Kai Jia, Zhenyuan Zhao et al. Nov 05, 2025 DOI: 10.1021/jacs.5c15231

The threat of an embodied virtual belly affects gastric feelings depending on somatic, interoceptive and alexithymic characteristics of healthy women

Scientific Reports Rudy Jeanne, Louise Dupraz, Jessica Bourgin et al. Nov 05, 2025 DOI: 10.1038/s41598-025-22694-9

Ultrafast Nonradiative Relaxation Limits the Efficiency of Photoinduced Bond Homolysis in Molecular LMCT Photocatalysts

Journal of the American Chemical Society Rachel Weiss, Bryan Kudisch Nov 05, 2025 DOI: 10.1021/jacs.5c10766

Study on effective frequency range of wheel-rail excitation for elevated high-speed railway

Scientific Reports Mengting Xing, Juxiang Zhu, Caiyou Zhao et al. Nov 05, 2025 DOI: 10.1038/s41598-025-22394-4

Development of Dual-Receptor Lysosome-Targeting Chimeras for Protein Degradation

Journal of the American Chemical Society Kun Wang, Ke Wang, Cong Wang et al. Nov 05, 2025 DOI: 10.1021/jacs.5c13695

The impact of continuous intravenous administration of heparin on coagulation dysfunction and organ failure in patients with sepsis

Scientific Reports Qinlong Sun, Si Wang, Xiaoxu Ding et al. Nov 05, 2025 DOI: 10.1038/s41598-025-22773-x

Personalized Cancer-Specific Protein-Aptamer Corona for Orthogonal Multiplex Cancer Diagnosis

Journal of the American Chemical Society Jinlong Fan, Baichuan Jin, Xin Dai et al. Nov 05, 2025 DOI: 10.1021/jacs.5c12860

Genotype environment interaction and stability analyses of advanced blast resistant rice genotypes derived from crossing MR219 x Pongsu Seribu-2

Scientific Reports Raieah Saiyedah Sabri, Mohd Y. Rafii, Samuel C. Chukwu et al. Nov 05, 2025 DOI: 10.1038/s41598-025-22481-6

Record Superconductivity in a Kagome Calcium Boride at High Pressure

Journal of the American Chemical Society Kexin Zhang, Jingkun Yu, Simin Li et al. Nov 05, 2025 DOI: 10.1021/jacs.5c11841

Fair-efficient allocation mechanism with meta-types resources in cloud computing

Scientific Reports Fengyue Zhang, Chunlei Shi Nov 05, 2025 DOI: 10.1038/s41598-025-22657-0

Quantum Defects Engineered in Chirality Pure Single-Wall Carbon Nanotubes for Enabling Ratiometric Sensing of Insulin

Journal of the American Chemical Society Ali A. Alizadehmojarad, Hohyung Kang, Gabriel Sánchez-Velázquez et al. Nov 05, 2025 DOI: 10.1021/jacs.5c12157

Bifunctional Iminophosphorane Superbases Enable the Highly Enantioselective Sulfa-Michael Addition to Fully Substituted Cyclopropene Carboxylic Acid Derivatives

Journal of the American Chemical Society Kang Yuan, Alberto I. Ristache, Szymon M. Kosc et al. Nov 05, 2025 DOI: 10.1021/jacs.5c07849

Fast and Reliable NMR-Based Fragment Scoring for Drug Discovery

Journal of the American Chemical Society Ridvan Nepravishta, Juan C. Munoz-Garcia, Kenneth Cameron et al. Nov 05, 2025 DOI: 10.1021/jacs.5c11092

Self-Organization of Microcompartments Powered by Enzyme-Driven Solutal Flows at the Water–Oil Interface

Journal of the American Chemical Society Pankaj S. Patwal, B. V. V. S. Pavan Kumar Nov 05, 2025 DOI: 10.1021/jacs.5c11877

Mechanism-Aware Deep Learning for Polar Reaction Prediction

Journal of the American Chemical Society Ryan J. Miller, Alexander E. Dashuta, Brayden Rudisill et al. Nov 05, 2025 DOI: 10.1021/jacs.5c16838

Interfacial Electric Fields Transform Brown Carbon Formation: Accelerate Radical Coupling toward Strong Light-Absorbing Products

Journal of the American Chemical Society Yangyang Liu, Kejian Li, Qiuyue Ge et al. Nov 05, 2025 DOI: 10.1021/jacs.5c08398

Activatable Fluorescent Probes for In Vivo and Ex Vivo Dynamic Profiling of Virus-Infected Macrophages

Journal of the American Chemical Society Jie Yu, Yan Zhang Nov 05, 2025 DOI: 10.1021/jacs.5c15321