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Molecular Charge Topologies Govern Polar Nematic Ordering

Journal of the American Chemical Society Viviana Palacio-Betancur, Nicholas E. Jackson Dec 24, 2025 DOI: 10.1021/jacs.5c18760

Reservoir characterization and rock typing of the gas-bearing El Wastani Formation, Simian Field, offshore Nile Delta

Scientific Reports Soliman Anwar, Hassan EL Kadi, Mohamed Reda et al. Dec 24, 2025 DOI: 10.1038/s41598-025-31825-1

Abstract Accurate prediction of reservoir performance in heterogeneous, clay-rich clastic systems remains a critical challenge in petrophysics. This study presents a novel, integrated workflow to overcome this challenge by delineating hydraulic flow units (HFUs) for robust rock typing and permeability prediction in the Pliocene El Wastani Formation, Simian field, offshore Nile Delta. Our methodology synergizes advanced petrophysical log analysis, conventional and special core analysis (SCAL), and sedimentological facies characterization to decipher controls on reservoir quality. The multi-technique approach included: spectral gamma ray (Th-K) cross-plots and Thomas-Stieber model analysis to characterize a dominant laminated illite/smectite clay assemblage; MDT pressure data to precisely define the Free Water Level at 2146 m TVDSS; and Pickett plot analysis to determine a formation water resistivity (Rw) of 0.16 Ω.m. Core-based Flow Zone Indicator (FZI) analysis of 208 samples, identified six distinct HFUs, each defined by a unique, high-fidelity porosity–permeability transform (R 2  = 0.70–0.98). This hydraulic zonation, validated by stratified modified Lorenz (SML) analysis, showed a strong correlation with sedimentary facies, linking high-quality flow units (HFU-4, HFU-5) to high-energy channel deposits. The results quantitatively demonstrate that reservoir quality is primarily governed by the interplay of depositional environment and consequent pore architecture. The superior performance of the RQI/FZI method over the Pittman R35 technique establishes it as the preferred predictive model. This integrated workflow provides a transformative framework for characterizing heterogeneous reservoirs, ultimately enabling optimized well placement, enhanced recovery, and improved reservoir management decisions in the Nile Delta and analogous basins worldwide.

Harnessing Truxone-Based Electrically Conductive Metal–Organic Framework for Electrochromism

Journal of the American Chemical Society Brianna Check, Ji Yong Choi, Joe Santarelli et al. Dec 24, 2025 DOI: 10.1021/jacs.5c17399

Neural architecture search using network embedding and generative adversarial networks

Scientific Reports Morteza Yousefi, Vahid Mehrdad, Mohammad Bagher Dowlatshahi Dec 24, 2025 DOI: 10.1038/s41598-025-30012-6

Unraveling the Humidity-Induced Phase Transition in CALF-20 via Machine Learning Potentials

Journal of the American Chemical Society Poobodin Mano, Klichchupong Dabsamut, Ching-Ming Wei et al. Dec 24, 2025 DOI: 10.1021/jacs.5c18944

Spatiotemporal evolution analysis of multiscale fracture dynamics in hydraulic shale stimulation via integrated acoustic emission and CT imaging

Scientific Reports Xu Wei, Meng Cai, Cuilong Kong et al. Dec 24, 2025 DOI: 10.1038/s41598-025-28004-7

Facilitating Quantitation of Mitochondrial G-Quadruplex DNA with an Iridium(III) Two-Photon Phosphorescence Lifetime Imaging Probe

Journal of the American Chemical Society Kai Xiong, Cheng Ouyang, Fa Wang et al. Dec 24, 2025 DOI: 10.1021/jacs.5c17409

A data-driven approach for risk assessment and material identification of buried objects using microwave measurements and neural networks

Scientific Reports Gülçin Yarımay, İbrahim Halil Bayat, Semih Doğu et al. Dec 24, 2025 DOI: 10.1038/s41598-025-28188-y

3D Macroporous Engineering of Metal Sulfide-Based Materials for High-Capacity and Ultrastable Potassium Storage under Room and Extreme Temperatures

Journal of the American Chemical Society Run-Hang Chen, Jian-Hua Long, Zi-Jian Chen et al. Dec 24, 2025 DOI: 10.1021/jacs.5c12045

Medical QA dialogue datasets in RAG systems performance evaluation and ChatGPT optimization

Scientific Reports Muretijiang Muhetaer, Ailimulati Yusupu, Wang Yifan et al. Dec 24, 2025 DOI: 10.1038/s41598-025-28015-4

Abstract This study evaluates the effectiveness of Chinese doctor–patient dialogues as retrieval sources for Retrieval-Augmented Generation (RAG) in clinical question answering. Using ChatGPT-3.5 as a baseline and extending to GPT-4o and GPT-5, we compare multiple retrieval pipelines, including dense retrieval, Cross-Encoder reranking, Reciprocal Rank Fusion (RRF), and Cascade RRF→Rerank. Experimental results show that dialogue-based retrieval significantly improves generation quality relative to direct prompting (e.g., ROUGE-1-f: +12.6%, BERTScore_F1: +1.5%, p  < 0.05). Among retrieval strategies, Rerank-only provides the best accuracy–latency balance, while the cascade pipeline introduces noise and yields no additional benefit. Under identical retrieval settings, GPT-4o achieves stronger automatic metrics and 4–5× lower latency, whereas GPT-5 receives slightly higher human preference scores (+ 0.08, p  < 0.001), indicating a trade-off between efficiency and perceived coherence. Expert evaluation further confirms improvements in readability, accuracy, and authenticity (all p  < 0.001). These findings highlight that data representation and metadata structure have a greater impact on RAG performance than retrieval algorithm complexity, offering practical guidance for reliable medical QA deployment.

Dynamics in Anisotropic Disassembly Process of DNA-Assembled Core–Satellite Superstructure of Gold Nanoparticles at Nanometer Order

Journal of the American Chemical Society Noriko Nakamura, Yuto Sahara, Yuki Yamazaki et al. Dec 24, 2025 DOI: 10.1021/jacs.5c16982

Effect of leguminous green manures on alleviating continuous cropping obstacles in muskmelon cultivation

Scientific Reports Yunfeng Ye, Guifen Li, Huayun Xie et al. Dec 24, 2025 DOI: 10.1038/s41598-025-28033-2

Macretina: a dataset, to support deep learning assisted retinopathy of prematurity diagnosis

Scientific Reports Urvesh Trivedi, Abhishek Srivastava, Pratik Mahajan Dec 24, 2025 DOI: 10.1038/s41598-025-31624-8

Small-Molecule Fe <sup>3+</sup> -Based Magnetic Resonance Imaging Probe Enables Noninvasive Imaging of Pancreatic Zn <sup>2+</sup> and β-Cell Function In Vivo

Journal of the American Chemical Society Jinyan Yi, Kexin Bian, Yun Xu et al. Dec 24, 2025 DOI: 10.1021/jacs.5c17216

PLX3397 attenuated tumor growth and remodeled tumor microenvironment of recurrent glioblastoma

Scientific Reports Chen Yang, Linzhi Cai, Xi Xiang et al. Dec 24, 2025 DOI: 10.1038/s41598-025-32943-6

Upcycling of Acid Waste Gases Using Asymmetric Atomic-Copper-Anchored Covalent Organic Framework Catalyst

Journal of the American Chemical Society Liping Zheng, Fengqing Liu, Yabin Zhou et al. Dec 24, 2025 DOI: 10.1021/jacs.5c13792

Evaluation of tuberculosis education effects on healthcare workers’ knowledge attitudes and practices in Jiangsu China 2019 to 2023

Scientific Reports Dian Jia, Honghuan Song, Guoli Li et al. Dec 24, 2025 DOI: 10.1038/s41598-025-28031-4

Vinylsilanes as Chain-Transfer Agents in Ethylene Polymerization: Direct Synthesis of Heterotelechelic Polyolefins

Journal of the American Chemical Society Zhi-Hao Chen, Feng Chen, Olafs Daugulis et al. Dec 24, 2025 DOI: 10.1021/jacs.5c15808

Whole transcriptome analysis reveals T cell signaling activation in septic patients with thrombocytopenia

Scientific Reports I-Chieh Chen, Yu-Han Jiang, Tzu-Hung Hsiao et al. Dec 24, 2025 DOI: 10.1038/s41598-025-32584-9

High-Density Palladium Single-Atom Catalysts for Photoinduced Tandem Decarbonylation/Carbonylative Reductive Coupling

Journal of the American Chemical Society Haolin Du, Qi Yu, Yucong Miao et al. Dec 24, 2025 DOI: 10.1021/jacs.5c12630