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Iyengar yoga and health education interventions for prolonged grief disorder in later life: feasibility of a randomized controlled pilot trial
General Framework for Geometric Deep Learning on Tensorial Properties of Molecules and Crystals
HMBOX1 plays a critical role in plumbagin-induced growth inhibition of hepatocellular carcinoma cells
Direct Charge-Transfer Transition Drives Triplet Generation and Photon Upconversion in 2D Hybrid Perovskites
Comparative analysis of the mechanical behavior and plastic deformation of empty and polyurethane foam-filled polyethylene tubes under lateral compression
Abstract In this research, the energy absorption and plastic deformation of circular polyethylene tubes under lateral compression were investigated, comparing empty tubes with those filled with polyurethane foam. The effects of tube length, diameter, wall thickness, and filler density on load-bearing capacity and energy absorption were evaluated. Absorbed energy and lateral load were found to increase with tube length, although the ductile response of polyethylene produced pronounced fluctuations in the load–displacement curve. Diameter influenced the two configurations differently: in empty tubes, smaller diameters yielded greater energy absorption, whereas in foam-filled tubes, larger diameters increased the flattening load and total absorbed energy, underscoring the critical role of diameter in foam-filled systems. Increasing wall thickness enhanced energy absorption, but polyurethane-foam filling was more effective and yielded a more consistent, predictable load–displacement response. Foam-filled tubes outperformed empty tubes overall; dominant damage mechanisms were identified as foam fracture, crushing, and densification. For applications prioritizing structural efficiency and specific absorbed energy (SAE), the use of higher-density polyurethane foam is recommended. Adhesion between the foam and the tube’s inner surface significantly increased peak load capacity. After relaxation, a uniform diameter reduction of approximately 12.7% was observed across specimens, indicating consistency in the final morphology. These findings provide guidance for the design of load-bearing systems employing polyethylene tubes and polyurethane foam.
Machine Learning-Guided Decoding Bioelectronic Signals of Photosynthetic Cyanobacterial Cells by Conducting Polymers
A high-resolution machine learning and multi-source remote sensing approach for estimating net primary productivity in campus green spaces
Zinc Plating on Copper Proceeds via Breakdown of a Capacitive Electric Double Layer
NIHSS mismatch as a predictor of early neurological improvement after mechanical thrombectomy
Cerium(IV) Phosphido Complexes
Proteomics analysis reveals progesterone receptor induced mitochondria-mediated apoptosis in breast cancer cells
In Situ Synthesis of Palladium Hydride as an Efficient and Stable Alkaline Hydrogen Oxidation Reaction Catalyst
A predictive model for vertical ground reaction force during incline push-ups
Mechanism of CO <sub>2</sub> Electrolysis with Heterogenized Molecular Iridium Catalysts Deciphered Using Operando Spectroscopy
Effects of glucagon-like peptide-1 on systemic hemodynamics, kidney function, and intrarenal oxygenation in sheep with sepsis-associated acute kidney injury
Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) reduce chronic kidney disease progression in people with type 2 diabetes mellitus. Sepsis is the leading cause of acute kidney injury (AKI). This study investigated whether GLP-1 is renoprotective in an ovine model of gram-negative septic AKI. Sixteen healthy merino ewes were surgically instrumented to measure mean arterial pressure, cardiac output, renal blood flow, renal cortical and medullary perfusion and oxygenation, and renal function. After a 5-day recovery period, sepsis was induced via continuous intravenous infusion of live Escherichia coli for 30 h. After 24 h, the sheep were randomized to receive an intravenous infusion of 3.6 pmol/kg/min GLP-1 ( n = 8) or a fluid-matched vehicle ( n = 8) for 6 h. After 24 h of sepsis, 7/8 sheep in each group developed AKI. GLP-1 treatment increased renal blood flow compared to placebo + 13 vs. − 3.4 ml/min difference (95% CI) = 16 (− 7–40) P = 0.0054), and maintained renal cortical oxygenation + 2.5 mmHg vs. = − 7.2 mmHg, difference (95% CI) = 9.7 (5.2–14.4) P < 0.001. GLP-1 maintained renal medullary perfusion + 1.7 vs. vehicle − 213 perfusion units, difference (95% CI) = 214 (− 21–450) P = 0.07. However, GLP-1 did not significantly improve the primary endpoint of renal medullary oxygenation − 1.6 vs. − 11.5, difference (95% CI) = 9.9 (− 6.8–26.7) P = 0.21. In an ovine model of gram-negative sepsis-associated AKI, GLP-1 infusion supported global renal perfusion, renal oxygen delivery, and cortical oxygenation but failed to improve renal medullary oxygenation and kidney function.
Nanopores with Ionic Memory in Oscillating Ion Current Signals
The effect of dental loupes on postural ergonomics during non-surgical periodontal therapy
Abstract To evaluate the effect of prismatic dental loupes on clinician posture during periodontal treatment performed by periodontology assistants. This cross-sectional observational study was conducted using a counterbalanced crossover design. Ten periodontology assistants performed supragingival scaling on two different patients; once with and once without loupes. Posture was assessed using Branson’s Posture Assessment Instrument (BPAI) through photographic evaluation at the 1st, 3rd, and 5th minutes of treatment. BPAI scores were compared between the two conditions, and correlations among posture components were analyzed. The use of loupes significantly improved overall posture, with lower total BPAI scores in the loupe condition. Significant improvements were observed in the hip, trunk, head/neck, and shoulder regions, while wrist posture did not differ significantly. A strong positive correlation was found between total BPAI and head/neck scores, indicating the influence of head/neck alignment on overall posture. Magnification loupes contribute to improved clinician posture, especially in the head/neck region, which strongly correlated with overall posture. The observed interdependence among body regions supports the need for holistic posture assessment. These findings highlight the ergonomic benefits of loupes in reducing musculoskeletal risks in dental practice. Incorporating magnification loupes into clinical practice may improve operator posture and contribute to long-term occupational health among dental professionals.