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Discover research articles across all indexed journals

Efficient apoptosis via double-strand breaks of DNA in human epithelial cells induced by non-thermal effect of high-field broadband terahertz waves

Scientific Reports Huan Zhou, Xingyi Wei, Xiao-Yu Peng et al. Jan 24, 2026 DOI: 10.1038/s41598-026-37373-6

Isotopic and defect analysis of enriched molybdenum oxide using EPR spectroscopy and DFT simulation

Scientific Reports Razieh Hosseini, Javad Karimi-sabet, Mehdi Janbazi et al. Jan 24, 2026 DOI: 10.1038/s41598-026-37195-6

Development and preliminary evaluation of real-time PCR assays for six lactic acid bacteria

Scientific Reports Shao-Ji Li, Biyan Cui, Wenhua Li et al. Jan 24, 2026 DOI: 10.1038/s41598-026-37047-3

Patient profiles, incidence and trends of lung cancer in Ethiopia from 2012 to 2023 using a cancer registry

Scientific Reports Nathan Estifanos, Gudina Egata, Adamu Addissie et al. Jan 24, 2026 DOI: 10.1038/s41598-026-36944-x

Integrated safety and microbiota profiling of fulvic acid formulations across in vitro and in vivo models

Scientific Reports Aleksandra Szwed-Georgiou, Przemysław Płociński, Marcin Włodarczyk et al. Jan 24, 2026 DOI: 10.1038/s41598-026-37331-2

Biofilms of Bacillus subtilis as biostimulants for plant resilience to drought and flooding

Scientific Reports Yu-Hsuan Chen, Jiou-Yi Liu, San-Gwang Hwang et al. Jan 24, 2026 DOI: 10.1038/s41598-026-36767-w

Secure, scalable, and interoperable healthcare data exchange using layer-2 ZK-rollups, smart contracts, and IPFS

Scientific Reports Abhinav Raghav, Aanjey Mani Tripathi, Niyaz Ahmad Wani et al. Jan 24, 2026 DOI: 10.1038/s41598-026-35289-9

Lung ultrasound B-line quantification in CTD-ILD: a cross-sectional single-center observational study

Scientific Reports Mengru Du, Jie Wang, Peng Lai et al. Jan 24, 2026 DOI: 10.1038/s41598-026-36874-8

Agreement between Scheimpflug-based optical biometer with partial coherence interferometry in patients with keratoconus

Scientific Reports Hassan Hashemi, Alireza Jamali, Morad Amir Ahmad et al. Jan 24, 2026 DOI: 10.1038/s41598-026-37513-y

Research on the molecular mechanism of celastrol targeting CTNNB1/STAT3 to inhibit uveal melanoma based on network pharmacology and multi-omics analysis

Scientific Reports Zhanglong Li, Ruofan Xi, Xudong Han et al. Jan 24, 2026 DOI: 10.1038/s41598-026-37061-5

Damage identification of reinforced concrete structure based on CNN-ICSA-GWELM model

Scientific Reports Weichen You Jan 24, 2026 DOI: 10.1038/s41598-025-32324-z

Clinical characteristics and associated complications in diabetic patients with Grade 1 stress injury based on a TriNetX Retrospective Study

Scientific Reports Ya-Huei Chen, Pi-Hua Chang, Mei-Yu Chang et al. Jan 24, 2026 DOI: 10.1038/s41598-025-34181-2

Sustainable operation of multi-energy systems under cooperative and non-cooperative strategies

Scientific Reports Hamid Karimi Jan 24, 2026 DOI: 10.1038/s41598-026-36536-9

Effects of dance mindfulness and combined interventions on social anxiety in left behind rural adolescents: a randomized controlled trial

Scientific Reports Xiaofen Ding, Qian Yang, Yuqin Sun et al. Jan 24, 2026 DOI: 10.1038/s41598-026-35039-x

Differences in red blood cell fatty acid profiles by type 2 diabetes status in early-stage chronic kidney disease

Scientific Reports Cindy George, Jillian Hill, N. Unati Nqebelele et al. Jan 24, 2026 DOI: 10.1038/s41598-026-36504-3

Combining response surface methodology and measurement system analysis to identify melt flow index of hygrothermal-sensitive composites

Scientific Reports Ning Su, Xiaoling Liu, Xiang Chen et al. Jan 24, 2026 DOI: 10.1038/s41598-025-33933-4

Optical coherence tomography and histological assessment of cutaneous vasculature and neural changes in long-term smokers: an exploratory study

Scientific Reports Abigail E. Doyle, Payal M. Patel, Sarina B. Elmariah et al. Jan 24, 2026 DOI: 10.1038/s41598-026-36667-z

An innovative data mining-driven optimisation modelling approach based on TAM for the design of elderly-centric ICT products

Scientific Reports Yu Cao, Xiaogang Yang, Shijian Luo et al. Jan 24, 2026 DOI: 10.1038/s41598-026-37657-x

Abstract To enhance the quality of life and health of the elderly, it is necessary to incorporate their specific needs into the design and manufacturing processes of Information and Communication Technology (ICT) products. However, these needs are often overlooked in product development, leading to poor user experiences and low adoption rates. To address this important issue, this study innovatively proposes a data mining-driven optimisation modelling approach. This approach first extracts key design elements from online reviews of elderly ICT products through text mining techniques such as data purification and Latent Dirichlet Allocation (LDA). These elements are then incorporated as external variables to construct a user needs integrated technology acceptance model (UN-TAM) for the elderly, which is validated using Structural Equation Modelling (SEM). Using the elderly smartwatch as a case study, four design optimisation parameters, functional architecture, human-computer interface, morphological aesthetics, and interaction mode, were extracted from a substantial database based on the elderly user comments. The proposed model establishes a quantitative mapping relationship among “design parameters, user perception, and behavioral intention”. The results indicate that these design parameters significantly influence the product acceptance through three distinct pathways: perceived ease of use (γ = 0.641, p  < 0.001), perceived usefulness (γ = 0.601, p  < 0.001), and perceived enjoyment (γ = 0.402, p  < 0.001). Specifically, functional architecture of the elderly-centric ICT products has the most substantial impact on perceived usefulness while the other three parameters predominantly influence perceived ease of use. The proposed data mining-driven optimisation modelling approach can be effectively used in designing and manufacturing elderly-centric ICT products.

DANEELpath open source digital analysis tools for histopathological research in neuroblastoma models

Scientific Reports Isaac Vieco-Martí, Amparo López-Carrasco, Samuel Navarro et al. Jan 24, 2026 DOI: 10.1038/s41598-026-37134-5

Evaluation of cytotoxicity, wound healing, and anti-inflammatory effects of netarsudil on human corneal epithelial cells

Scientific Reports Kwang Eon Han, Jung Hyo Ahn, Su-jin Kim et al. Jan 24, 2026 DOI: 10.1038/s41598-026-36860-0