Browse Articles

Stereodivergent Inverse Electron-Demand Diels–Alder Reactions Enabled by Modification of Prolinol-Derived Catalysts

Optimizing the potential use of waste palm oil clinker powder in cementitious grouts for semiflexible pavements using response surface methodology

Coexistence of Ferroelectricity and Antiferroelectricity in a Photoactive Low-Dimensional Coordination Single-Phase Crystal

Diel movements and flight altitudes of the European storm-petrel in the North Atlantic and their implications for conservation

FDMNet: frequency-domain modulation network for robust object detection in hazy aerial imagery

Photoelectrocatalytic Chemical Pathways in Photoassisted Lithium–Sulfur Batteries via a Multiscale Graph-Based Machine Learning Framework

Effects of robotic hand-assisted rehabilitation on motor function and daily living activities in acute stroke: a randomized controlled trial

CIPHER-seq enables intracellular multimodal profiling of cytokine responses in single immune cells

Abstract Single-cell RNA sequencing inadequately predicts protein abundance, particularly for intracellular cytokines. We developed CIPHER-seq (Cytokine Intracellular Protein High-throughput Expression with RNA-sequencing), enabling simultaneous quantification of intracellular proteins and transcriptomes. This system provides five layers of analysis. CIPHER-seq matched commercial protocols in immune cell recovery while significantly reducing mitochondrial stress signatures. Applied to stimulated PBMCs, CIPHER-seq resolved robust cytokine induction and metabolic remodeling, establishing a streamlined platform for intracellular multimodal profiling.

Direct Observation of Selective Migratory Insertion of Unactivated Terminal Alkenes into Ir–N Bonds

Altitudinal influence on chemical composition, antioxidant potential and methyl ester profile of kapok seed oil: a sustainable biodiesel option

Mechanistic Continuum from Stepwise to Concerted Proton-Coupled Electron Transfer Pathways at a Synthetic Tricopper Cluster

Plasma and aqueous humor levels of Maresin-1 in patients with diabetic retinopathy

Biomimetic Liquid–Solid Interfaces for Selective and Moisture-Tolerant CO ₂ Chemisorption

Stabilizing Covalent Organic Frameworks through Hydrogen Bonding Bridges for Polyamine Entanglement toward Carbon Capture from Point-Source Emissions

A Synergistic Theoretical and Experimental Study on Ternary La–B–H Systems under Pressure

Nanopore-Based Glycan Sequencing via a Fragmentation-Reassembly Strategy

Selective Boron Occupation at Tetrahedral Cation Sites in Co ₃ O ₄ Enables Self-Adaptive Electron Transfer for Enhanced Water Oxidation

Hydration-Controlled Proton Transport in Respiratory Complex I

Ascertaining the Transient State Pivotal for Fast Carrier Migration in Halide Perovskites

Highly Selective Electrochemical Bicarbonate Conversion across C ₁ and C ₂ Products by Interface-Modulation with a Stripping Compartment