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Schrödinger’s Cancer

New England Journal of Medicine Mark Earnest Jan 16, 2025 DOI: 10.1056/nejmp2408841

Epidemiology of sickle cell disease in tribal population of Southern Rajasthan, India

Scientific Reports Anil Purohit, Ramesh K. Huda, Suman S. Mohanty et al. Jan 16, 2025 DOI: 10.1038/s41598-024-81224-1

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis

New England Journal of Medicine Philippe Généreux, Allan Schwartz, J. Bradley Oldemeyer et al. Jan 16, 2025 DOI: 10.1056/nejmoa2405880

Study of physiochemical properties of trisubstituted pyrazole derivatives using polar aprotic solvents

Scientific Reports Poonam Devi, Hardeep Anand, Rashmi Pundeer et al. Jan 16, 2025 DOI: 10.1038/s41598-024-69167-z

Livedo Racemosa

New England Journal of Medicine Wei-Yao Wang, Cheng-Che Eric Lan Jan 16, 2025 DOI: 10.1056/nejmicm2410678

Sex-specific response of intramuscular fat to diet-induced obesity in rats

Scientific Reports Hannah E. Smith, Nada Abughazaleh, Ruth A. Seerattan et al. Jan 16, 2025 DOI: 10.1038/s41598-024-85084-7

Challenges to the Future of a Robust Physician Workforce in the United States

New England Journal of Medicine Rochelle P. Walensky, Nicole C. McCann Jan 16, 2025 DOI: 10.1056/nejmsr2412784

Author Correction: Design of retrofit flue gas (CO2) scrubber for dependable clean energy at the Duvha Coal Power Plant

Scientific Reports Hlamalani Innocent Baloyi, Leonard U. Okonye, Jianwei Ren Jan 16, 2025 DOI: 10.1038/s41598-024-84232-3

Burnout, Depression, and Diminished Well-Being among Physicians

New England Journal of Medicine Jan 16, 2025 DOI: 10.1056/nejmc2415470

B cells enhance IL-1 beta driven invasiveness in triple negative breast cancer

Scientific Reports Nicole J. Toney, Lynn M. Opdenaker, Lisa Frerichs et al. Jan 16, 2025 DOI: 10.1038/s41598-025-86064-1

Finerenone in Heart Failure with Preserved Ejection Fraction

New England Journal of Medicine Jan 16, 2025 DOI: 10.1056/nejmc2414955

Comparison of management options for spontaneous bleeding into soft tissues in patients with COVID-19

Scientific Reports A. E. Tyagunov, D. Y. Trudkov, A. Y. Polyaev et al. Jan 16, 2025 DOI: 10.1038/s41598-025-85454-9

Case 2-2025: A 21-Year-Old Man with Loss of Consciousness and a Fall

New England Journal of Medicine Eric F. Shappell, Brooks P. Applewhite, Sharl S. Azar et al. Jan 16, 2025 DOI: 10.1056/nejmcpc2412511

High-resolution X-ray phase-contrast tomography of human placenta with different wavefront markers

Scientific Reports Sara Savatović, Davis Laundon, Fabio De Marco et al. Jan 16, 2025 DOI: 10.1038/s41598-025-85105-z

Abstract Phase-contrast micro-tomography ( $$\upmu$$ CT) with synchrotron radiation can aid in the differentiation of subtle density variations in weakly absorbing soft tissue specimens. Modulation-based imaging (MBI) extracts phase information from the distortion of reference patterns, generated by periodic or randomly structured wavefront markers (e.g., gratings or sandpaper). The two approaches have already found application for the virtual inspection of biological samples. Here, we perform high-resolution $$\upmu$$ CT scans of an unstained human placenta specimen, using MBI with both a 2D grating and sandpaper as modulators, as well as conventional propagation-based imaging (PBI). The 3D virtual representation of placenta offers a valuable tool for analysing its intricate branching villous network and vascular structure, providing new insights into its complex architecture. Within this study, we assess reconstruction quality achieved with all three evaluated phase-contrast methods. Both MBI datasets are processed with the Unified Modulated Pattern Analysis (UMPA) model, a pattern-matching algorithm. In order to evaluate the benefits and suitability of MBI for virtual histology, we discuss how the complexities of the technique influence image quality and correlate the obtained volumes to 2D techniques, such as conventional histology and X-ray fluorescence (XRF) elemental maps.

Centrophilic retrotransposon integration via CENH3 chromatin in Arabidopsis

Nature Sayuri Tsukahara, Alexandros Bousios, Estela Perez-Roman et al. Jan 16, 2025 DOI: 10.1038/s41586-024-08319-7

Fracture Prevention with Infrequent Zoledronate in Women 50 to 60 Years of Age

New England Journal of Medicine Mark J. Bolland, Zaynah Nisa, Anna Mellar et al. Jan 16, 2025 DOI: 10.1056/nejmoa2407031

A hybrid critical channels and optimal feature subset selection framework for EEG fatigue recognition

Scientific Reports Hanying Guo, Siying Chen, Yongjiang Zhou et al. Jan 16, 2025 DOI: 10.1038/s41598-025-86234-1

Publisher Correction: Preliminary investigation on the establishment of a new meibomian gland obstruction model and gene expression

Scientific Reports Ming Sun, Huanmin Cheng, Zheng Yang et al. Jan 16, 2025 DOI: 10.1038/s41598-024-85098-1

Self-referential belief shares common neural correlates with general belief

Scientific Reports Emily Bruns, Immanuel Scholz, Georgia Koppe et al. Jan 16, 2025 DOI: 10.1038/s41598-024-84445-6

Abstract Belief processing and self-referential processing have been consistently associated with cortical midline structures, and cortical regions such as the vmPFC have been implicated in general belief processing. The neural correlates of self-referential belief are yet to be investigated. In this fMRI study, we presented 120 statements with trait adjectives to N = 27 healthy participants, who subsequently judged whether they believed these trait adjectives applied to themselves, a close person, or a public person. Thereafter, participants rated their certainty in this judgment. Expectedly, self-referential processing evoked a large cluster in the vmPFC, ACC, and dmPFC. For belief, we found a cluster in the vmPFC, ACC, and amPFC during statement presentation, partially overlapping with that for self-referential processing. The cluster for self-belief vs. disbelief was similar in location and size to that for general belief processing. For uncertainty, we found dmPFC activation. We replicated vmPFC involvement in belief processing and found a common neural correlate for belief and self-belief in the vmPFC. Furthermore, we replicated the role of the dmPFC in uncertainty, supporting a dual neural process model of belief and certainty.

HLA-I aberrations in cutaneous T-cell lymphoma

Blood Ting Zhou, Kojo S. J. Elenitoba-Johnson Jan 16, 2025 DOI: 10.1182/blood.2024027135