Browse Articles

Estimation of stationary and non-stationary moving average processes in the correlation domain

This paper introduces a novel approach for the offline estimation of stationary moving average processes, further extending it to efficient online estimation of non-stationary processes. The novelty lies in a unique technique to solve the autocorrelation function matching problem leveraging that the autocorrelation function of a colored noise is equal to the autocorrelation function of the coefficients of the moving average process. This enables the derivation of a system of nonlinear equations to be solved for estimating the model parameters. Unlike conventional methods, this approach uses the Newton-Raphson and Levenberg–Marquardt algorithms to efficiently find the solution. A key finding is the demonstration of multiple symmetrical solutions and the provision of necessary conditions for solution feasibility. In the non-stationary case, the estimation complexity is notably reduced, resulting in a triangular system of linear equations solvable by backward substitution. For online parameter estimation of non-stationary processes, a new recursive formula is introduced to update the sample autocorrelation function, integrating exponential forgetting of older samples to enable parameter adaptation. Numerical experiments confirm the method’s effectiveness and evaluate its performance compared to existing techniques.

Who is American? A comprehensive analysis of the American = White/Foreign = Asian stereotype (2007–2023)

Perceived stress and coping strategies used by undergraduate dental students: An observational study

Studies around the world have reported that dental students experience higher stress compared to medical students. Prolonged and high perceived stress can be of a significant concern as it affects the personal, psychological, and professional well-being of the student, affecting quality of life. The aim of the study was to describe the perceived stress and coping strategies that undergraduate students at dental schools of Lahore, Pakistan employ. This observational study was conducted in year 2023 to report perceived stress and coping strategies among 720 undergraduate dental students of Lahore using modified Dental Environment Stress (DES) and brief Coping Orientation to Problems Experienced (COPE) questionnaires. Categorical variables such as sex, year of study (year 1 till 4), and responses to DES stress domains, stress-related items, COPE domains, and COPE-related items were computed into frequencies and percentages. Mean item scores of stress domains, stress-related items, COPE domains, and COPE-related items were presented with standard deviations (SD). Groups wise comparisons were done using Mann Whitney U and Kruskal Wallis H tests. P value < 0.05 was considered statistically significant. The majority of the undergraduate dental students perceived moderate amount of stress. Item “overload feeling due to huge syllabus” had the highest mean stress score (3.49±0.76) and “language barrier” had the lowest mean stress score (1.75±0.92). Female students had higher mean stress scores than the male students in all of the DES domains. Mean stress scores were higher in year 4 students for “workload”, “self-efficacy beliefs”, “faculty and administration”, “clinical training”, and “social stresses” compared to other years. “Religion” was the highest- and “denial” was the lowest-ranked coping strategies. Female students employed “active coping”, “positive reframing”, “religion”, “venting”, “self-blame”, “denial”, and “behavioral disengagement” coping strategies more than males. Moreover, final year dental students used “instrumental support”, “humor”, “self-blame”, “denial”, and “behavioral disengagement” coping strategies more than year 1 and 2 students. Sex and year of study can influence the degree of perceived stress and choice of coping strategies employed to overcome stressful situations. For the emotional, psychological, and professional well-being of undergraduate students, institutions must provide a nurturing and positive learning environment implementing strategies for stress prevention and management.

Construction of an evaluation indicator system for the integrated development of sports, culture and tourism based on tourist perceptions

A safe-enhanced fully closed-loop artificial pancreas controller based on deep reinforcement learning

Patients with type 1 diabetes and their physicians have long desired a fully closed-loop artificial pancreas (AP) system that can alleviate the burden of blood glucose regulation. Although deep reinforcement learning (DRL) methods theoretically enable adaptive insulin dosing control, they face numerous challenges, including safety and training efficiency, which have hindered their clinical application. This paper proposes a safe and efficient adaptive insulin delivery controller based on DRL. It employed ten tricks to enhance the proximal policy optimization (PPO) algorithm, improving training efficiency. Additionally, a dual safety mechanism of ’proactive guidance + reactive correction’ was introduced to reduce the risks of hyperglycemia and hypoglycemia and to prevent emergencies. Performance evaluations in the Simglucose simulator demonstrate that the proposed controller achieved an 87.45% time in range (TIR) median, superior to baseline methods, with a lower incidence of hypoglycemia, notably eliminating severe hypoglycemia and treatment failures. These encouraging results indicate that the DRL-based fully closed-loop AP controller has taken an essential step toward clinical implementation.

Study on spatial correlation and driving factors of industrial carbon emission in the Hefei metropolitan area based on SNA-QAP method

Implementing psychosocial interventions for teachers’ mental health: Protocol for integrating scoping review with teachers lived experiences in LMICs

Introduction Teachers are pivotal in shaping educational environments and student development but face significant occupational stress and high rates of mental problems. Despite the availability of various psychosocial interventions, comprehensive evidence of their effectiveness and implementation is limited for this occupational group, especially in low- and middle-income countries (LMICs). This mixed methods study aims to conduct a scoping review of characteristics, effectiveness, and implementation outcomes of psychosocial interventions for teachers’ mental health and mental problems, integrating these with teachers’ lived experiences to inform the implementation of mental health interventions in LMICs. Methods The study combines a scoping review with insights from an advisory group of teaching professionals with relevant lived experiences (PWLEs). The review will focus on examining psychosocial interventions studies promoting mental health or addressing mental problems among grade 1–12 school teachers of all genders, ages and contexts, except those working in specialized settings, such as special education centers, or disaster- or crisis-stricken zones. Intervention studies exclusively focusing on physical health or job-related outcomes will be excluded. Using pre-defined search terms, quantitative and qualitative research studies, including unpublished literature, will be searched across multiple databases. Titles and abstracts of identified studies will be screened against inclusion criteria, and the potentially relevant sources will be retrieved in full. Data will be extracted using a data extraction sheet developed for the study covering variables related to participant characteristics, intervention characteristics, study context, effectiveness and implementation outcomes. A purposively selected sample of 10 PWLEs will form the study advisory group and participate in four online workshop-group discussions. The meetings will include a presentation of the scoping review findings, followed by discussions on the relevance of these intervention packages for LMICs, adaptations needed to make them acceptable among school teachers and feasible for delivery in low-resourced settings like India. The synthesis of the data will employ narrative and thematic approaches to generate actionable insights for implementing psychosocial interventions in LMICs. Discussion This study will provide comprehensive evidence on the characteristics and outcomes of psychosocial interventions for teachers’ mental health and mental problems. By integrating insights from teachers with relevant lived experiences, the study will provide practical guidelines for adapting and implementing psychosocial interventions among school teachers in LMICs. Trial registration Review registration number: Open Science Framework, doi.org/10.17605/OSF.IO/GF59J.

Efficacy of malic and tartaric acid in mitigation of cadmium stress in Spinacia oleracea L. via modulations in physiological and biochemical attributes

An evolutionary game theory analysis on the environmental impact of discharging Fukushima’s nuclear wastewater: International stakeholders and strategic dynamics

On August 24, 2023, Japan controversially decided to discharge nuclear wastewater from the Fukushima Daiichi Nuclear Power Plant into the ocean, initiating intense domestic and global debates. This study employs a mixed-method approach, integrating quantitative evolutionary game theory and qualitative data analysis to explore the strategic dynamics among Japan, other nations, and the Japan Fisheries Association regarding this decision. The data includes international environmental reports and economic statistics, served as the basis for simulating decision-making processes under various legal, economic, and environmental pressures. The evolutionary game theory model is used to predict and analyze three evolutionarily stable strategies (ESS), detailing the transition from the initiation to cessation of wastewater discharge. These strategies highlight the necessity for international cooperation, rigorous scientific research, public education, and effective wastewater treatment methods. This study aims to provide both a theoretical framework and practical guidance to foster a global consensus on nuclear wastewater management, which is vital for marine conservation and sustainable development.

Multi scale multi attention network for blood vessel segmentation in fundus images

More on mobility and sedentism: Changes in adaptation from Upper Paleolithic to Incipient Jomon, Tanegashima Island, southern Japan

Sedentism is an adaptive alternative in human societies which is often associated with the emergence of complex societies in the Holocene. To elucidate the factors and processes of the emergence of sedentary societies, continuous accumulation of case studies based on robust evidence from across the world is required. Given abundant archaeological and geological evidence from the late Pleistocene to early Holocene, Tanegashima Island, situated in the southern Japanese Archipelago of the northwestern Pacific Rim, has significant potential to unravel factors and processes of sedentism. Our study evaluates long-term change in hunter-gatherer mobility on Tanegashima Island from the Upper Paleolithic to Incipient Jomon (ca.36,000–12,800 cal BP). Based on Bayesian age modelling, we performed diachronic analyses on lithic toolkit structure, lithic reduction technology, lithic raw material composition, and occupation intensity. The results illustrate that settlement-subsistence strategies on Tanegashima primarily correspond to the change in environmental conditions, mainly food resources, and foragers increased their degrees of sedentism when abundant forest existed. More important is that highly stable sedentism, which is not observed until the Incipient Jomon, depends not only on such a productive environment, but also on the increase in population size. High occupation intensity during the Incipient Jomon on the island is likely attributed to an influx of people from Kyushu proper. Although the relationship between cause and effect of these factors is still to be clarified in future work, our study provides insights on the fundamental causes of sedentism in the temperate forest of the late Pleistocene.

Factors associated with post-traumatic stress symptoms in healthcare providers after performance of cardiopulmonary resuscitation: a mixed-methods study

Comparison of behind-the-ear vs. off-the-ear speech processors in cochlear implants: A systematic review and narrative synthesis

Background Cochlear implants (CI) with off-the-ear (OTE) and behind-the-ear (BTE) speech processors differ in user experience and audiological performance, impacting speech perception, comfort, and satisfaction. Objectives This systematic review explores audiological outcomes (speech perception in quiet and noise) and non-audiological factors (device handling, comfort, cosmetics, overall satisfaction) of OTE and BTE speech processors in CI recipients. Methods We conducted a systematic review following PRISMA-S guidelines, examining Medline, Embase, Cochrane Library, Scopus, and ProQuest Dissertations and Theses. Data encompassed recipient characteristics, processor usage, speech perception, and non-audiological factors. Studies were assessed for quality and risk of bias by using Newcastle-Ottawa Scale (NOS). Results Nine studies involving 204 CI recipients, with a mean age of 49.01 years and 6.62 years of processor use, were included. Audiological results indicated comparable performance in quiet environments, with a slight preference for OTE in noisy conditions. For non-audiological factors, OTE processors excelled in comfort, handling, and aesthetics, leading to higher satisfaction. More data on medical complications and long-term implications is needed. Conclusion OTE processors may offer comparable performance to BTE processors in certain conditions, though not universally across all audiological outcomes. Interpretation depends on settings, processor generation, and testing paradigms. However, non-audiological factors might favour OTE. Understanding current literature may guide professionals in selecting suitable processors for CI recipients.

Optimized design and experimental analysis of the vertical mixing plow for enhancing planosol improvement machine

Abstract Improved soil fertility to sustain crop productivity is important to enhance agroecosystem services. To address the low nutrient content, subsoil compaction, and poor root penetration in Planosol, a new machine was designed to improve these conditions. This machine integrates subsoil mixing and fertilizer application. The paper details the machine’s structure and working principle, focusing on optimizing the vertical mixing plow. Furthermore, discrete element method simulations were conducted, using tillage depth, forward speed, and plow height as factors, with soil mixing rate and tractive resistance serving as the evaluation indicators. Results showed optimal performance at 553 mm tillage depth, 1 m/s speed, and 227 mm plow height, with tractive resistance of 7460.5 N and a soil mixing rate of 72.1%. Field trials and soil improvement tests based on optimized parameters confirmed the accuracy and reliability of the simulation results. Compared to the Shallow plowing and subsoiling area, the subsoil mixing improvement area showed significant improvement, with a yield increase of 16.4–18.9% over two years.

Maternal mental health matters: Indicators for perinatal mental health—A scoping review

Perinatal mental health disorders are a significant contributor to morbidity and mortality in childbearing women. The World Health Organization recommends all women be screened for mental health disorders postnatally and have diagnostic and management services available. There are, however, currently no global indicators in use which measure the status and progress of perinatal mental health. The aim of this scoping review was to identify existing perinatal mental health indicators and propose a core set which could be used at a global level. We used the Global Perinatal Mental Health Theory of Change as the conceptual framework. We found 25 indicators for PMH aligned with the Global Perinatal Mental Health Theory of Change, which were condensed to form a core set of nine indicators These core indicators include the proportion of women with depression, anxiety, post-traumatic stress disorder, psychosis, or adjustment disorders in the perinatal period; the proportion of women screened for these services; the proportion who have access to services following a positive diagnosis; and, the proportion of healthcare providers trained to provide mental health care. This review forms part of the foundational work for the development of a global monitoring framework which would be able to monitor progress towards the provision of universal high quality perinatal mental health care.

Unbiased picture of the ligand docking process for the hevein protein–oligosaccharide complex

Investigation of the canine elbow joint innervation in 100 joints

The canine elbow joint is innervated by four nerves: the musculocutaneous, median, radial, and ulnar nerves. There is little data in the veterinary literature examining the course of the articular branches of those nerves. There is also no agreement as to their anatomical location in the joint capsule nor to their number. The lack of such data prompted us to undertake studies to analyze the course of these nerves and the number and location of their articular branches in both left and right joint capsules in 50 dogs (with a total of 100 joints). No within-individual differences in the number of branches or their location were found between left and right joints. There was between-joint variation in the number of articular branches of the median, musculocutaneous, and radial nerves. There was also variation in the location of the branches of the median and radial nerves. Some of the results are different from those previously reported in the literature. The obtained data allow to further detail anatomical descriptions of the dog elbow innervation. Additionally, they may constitute the basis for developing new surgical procedures, improving existing procedures, or allow a better preparation for possible differences during operations of this joint.

Projecting the global potential distribution of nine Rhododendron Subgenus Hymenanthes species under different climate change scenarios

Antioxidant and anti-inflammatory function of walnut green husk aqueous extract (WNGH-AE) on human hepatocellular carcinoma cells (HepG2) treated with t-BHP

Oxidative damage, oxidative inflammation, and a range of downstream diseases represent significant threats to human health. The application of natural antioxidants and anti-inflammatory agents can help prevent and mitigate these associated diseases. In this study, we aimed to investigate the effectiveness of walnut green husk (WNGH) as an antioxidant and anti-inflammatory agent in an in vitro setting. HepG2 cells were treated with tert-butyl hydroperoxide (t-BHP) to establish a cellular model of oxidative damage and inflammation. We assessed the biocompatibility of walnut green husk aqueous extract (WNGH-AE) on HepG2 cells using MTT and LDH assays (WNGH-AE concentration: 0.05, 0.1, 0.2, 0.4, 0.8, 1.6, 3.2, 6.4, and 12.8 mg/mL). Additionally, we measured intracellular oxidative stress indicators, such as ROS and 8-OHdG, along with inflammatory factors TNF-α and IL-1β through ELISA to evaluate the antioxidant and anti-inflammatory capacity of WNGH-AE (concentration: 0.025, 0.05, 0.1 mg/mL) in HepG2 cells. We also determined the free radical scavenging capacity of various extracts of WNGH using DPPH and ·OH methods. The total phenols, total polysaccharides, and total flavonoids in WNGH-AE were analyzed using the Folin-Ciocalteu’s reagent, the phenol-sulfuric acid method, and the spectrophotometry, respectively. The bioactive components of WNGH-AE were analyzed using LC-MS/MS. Our results demonstrated that WNGH-AE was highly biocompatible with HepG2 cells. The antioxidant effect of WNGH-AE involved the scavenging of intracellular ROS, while its anti-inflammatory effect was linked to the down-regulation of the NF-κB pathway. Compared to other extractants (ethyl acetate, n-butanol, 75% ethanol, and petroleum ether), WNGH-AE exhibited the strongest free radical scavenging ability. Through LC-MS/MS analysis, we identified 403 compounds in WNGH-AE, with gentisic acid being the most abundant and possessing high antioxidant capacity, suggesting it may be a key active component contributing to the antioxidant activity of WNGH-AE. In conclusion, our findings indicate that WNGH-AE is a natural, high-quality antioxidant and anti-inflammatory biomaterial deserving further research and development, with significant potential applications in healthcare. (311 words)

Knowledge of gym goers on myths and truths in resistance training

Abstract Over the last decades, resistance training (RT) has experienced a surge in popularity, and compelling evidence underpins its beneficial effects on health, well-being, and performance. However, sports and exercise research findings may translate poorly into practice. This study investigated the knowledge of Austrian gym-goers regarding common myths and truths in RT. Based on topical systematic reviews (n = 45), a digital questionnaire with 14 statements on RT methods and practices, randomly phrased as myths or truths, was administered to Austrians exercising in local fitness centres. Chi-squared tests were used to check if a majority correctly identified true and false statements. A total of n = 721 (30.1 ± 14 years, 454 males) out of n = 790 contacted individuals completed the survey (response rate: 91.2 percent). Five out of fourteen statements (truth: protein augments strength and hypertrophy, creatine augments strength, superiority of full- vs. partial-ROM RT for hypertrophy; myth: RT reduces flexibility, low-load, high-volume RT is as effective as high-load RT with regard to maximal strength) were identified correctly by a majority (p < .01). The awareness of the scientific evidence on RT is low among gym-goers. Upcoming studies should be geared to improve science communication.