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Ordered Interfacial Water Generated at Poly(ionic liquid) Membrane Surface Imparts Ultrafast Water Transport and Superoleophobicity

Ambient Temperature Isolation of a Monatomic Boron(0) Complex

Improved Ammonia Synthesis and Energy Output from Zinc-Nitrate Batteries by Spin-State Regulation in Perovskite Oxides

Observation of the Protein-Inorganic Interface of Ferritin by Cryo-Electron Microscopy

Erratum: Binder et al., “Reducing Filamin A Restores Cortical Synaptic Connectivity and Early Social Communication Following Cellular Mosaicism in Autism Spectrum Disorder Pathways”

Precise Synthesis of Complex Si–Si Molecular Frameworks

Tetra-Cationic Distibane Stabilized by Bis(α-iminopyridine) and Its Reactivity

Fermi Level Equilibration and Charge Transfer at the Exsolved Metal-Oxide Interface

Emergence of Chirality in an Optically Active Two-Dimensional Crystal with a Spiral Surface Pattern

Crafting Hollow Spheres via Bulk Ice Melting with ppb-Level Gas Sensing Performance

3D Covalent Organic Framework Membrane with Interactive Ion Nanochannels for Hydroxide Conduction

Readily Accessible, Versatile, and Adaptive Biaxially Chiral Chromophores

Supramolecularly Built Local Electric Field Microenvironment around Cobalt Phthalocyanine in Covalent Organic Frameworks for Enhanced Photocatalysis

B, N Codoped Defective Reduced Graphene Oxide as a Highly Efficient Frustrated Lewis Pairs Catalyst for the Selective Hydrogenation of α,β-Unsaturated Aldehydes to Unsaturated Alcohols

Pseudopterosin Biosynthesis: Unravelling a Decades Old Problem in Animal Specialized Metabolism

Facile Access to Quaternary Carbon Centers via Ni-Catalyzed Arylation of Alkenes with Organoborons

Dual Activation Modes Enable Bifunctional Catalysis of Aldol Reactions by Flexible Dihydrazides

Complementary Organization of Mouse Driver and Modulator Cortico-thalamo-cortical Circuits

Corticocortical (CC) projections in the visual system facilitate hierarchical processing of sensory information. In addition to direct CC connections, indirect cortico-thalamo-cortical (CTC) pathways through the pulvinar nucleus of the thalamus can relay sensory signals and mediate cortical interactions according to behavioral demands. While the pulvinar connects extensively to the entire visual cortex, it is unknown whether transthalamic pathways link all cortical areas or whether they follow systematic organizational rules. Because mouse pulvinar neurons projecting to different areas are spatially intermingled, their input/output relationships have been difficult to characterize using traditional anatomical methods. To determine the organization of CTC circuits, we mapped the higher visual areas (HVAs) of male and female mice with intrinsic signal imaging and targeted five pulvinar→HVA pathways for projection-specific rabies tracing. We aligned postmortem cortical tissue to in vivo maps for precise quantification of the areas and cell types projecting to each pulvinar→HVA population. Layer 5 corticothalamic (L5CT) “driver” inputs to the pulvinar originate predominantly from primary visual cortex (V1), consistent with the CC hierarchy. L5CT inputs from lateral HVAs specifically avoid driving reciprocal connections, consistent with the “no-strong-loops” hypothesis. Conversely, layer 6 corticothalamic (L6CT) “modulator” inputs are distributed across areas and are biased toward reciprocal connections. Unlike previous studies in primates, we find that every HVA receives disynaptic input from the superior colliculus. CTC circuits in the pulvinar thus depend on both target HVA and input cell type, such that driving and modulating higher-order pathways follow complementary connection rules similar to those governing first-order CT circuits.

Concise Synthesis of (−)-Veratramine and (−)-20-<i>iso</i>-Veratramine via Aromative Diels–Alder Reaction

OPTO: Automated Optimization for Solid-State NMR Spectroscopy