Scientific Reports
Articles in this Issue
Exploring Pharmacokinetic interactions between SHR8554, a µ-opioid receptor biased agonist, and Itraconazole in healthy Chinese subjects
Abstract SHR8554 is a biased agonist for µ-opioid receptors, which was under investigation as an alternative therapy for clinical pain. This open, fixed-sequence study evaluated its pharmaco...
Re-identification assistance and multi-stage association for pedestrian multi-object tracking
Comparison of endoscopic healing and durability between combination therapy with infliximab and azathioprine versus infliximab monotherapy in pediatric Crohn’s disease
Predicting boiling heat flux, heat transfer coefficient, and regimes Non-intrusively using external acoustics and deep learning
Abstract Accurate monitoring of boiling heat transfer is critical for the safety and efficiency of high energy-density systems, including data center cooling, nuclear reactors, and industria...
A multi stage deep learning approach for real-time vehicle detection, tracking, and speed measurement in intelligent transportation systems
Effects of varying weld speeds on the microstructure, mechanical properties, and corrosion behavior of clad rebars in a marine environment
Matrix metalloproteinases as diagnostic and prognostic biomarkers in skin cutaneous melanoma and squamous cell carcinoma
Abstract Skin cutaneous melanoma (SKCM) and squamous cell carcinoma (SCC) are two prevalent forms of skin cancer, both characterized by extensive remodeling of the extracellular matrix (ECM)...
The impact of institutional openness on the synergistic effect of air pollution reduction and carbon reduction in China
Experimental investigation of blasting stress wave attenuation in sandstone with columnar charging using high-speed DIC technique
Equitable urban green space planning for sustainable cities: a GIS-based analysis of spatial disparities and functional strategies
Accessibility and influencing factors of leisure agriculture demonstration sites in Guangdong Province based on GWR model
Glucose homeostasis and cognitive functions in schizophrenia: a systematic review and meta-analysis
Abstract Schizophrenia is a lifelong mental disorder associated with cognitive dysfunctions. Comorbid metabolic dysregulations, such as diabetes and insulin resistance, may further deteriora...
Automatic detection of orthodontically induced external root resorption based on deep convolutional neural networks using CBCT images
A 13.06 Ma widespread ignimbrite in the Pannonian Basin captured a snapshot of shallow marine to coastal environment in Central Paratethys
Abstract Voluminous Miocene silicic volcanism sourced mainly from the extensional Pannonian Basin played a major role in the evolution of the Central Paratethys. Here, we identify a widely d...
Design and numerical study of active cooling device for high temperature oil and gas wells based on regenerative refrigerator
Ionic liquid-assisted biomass-derived N, S-doped carbon dots with enhanced corrosion inhibition
Body roundness index and mental health in middle-aged and elderly adults: a prospective cohort study
Mental health trajectories, resilience and psychosocial factors in palliative care workers frequently exposed to death
Dual functions of the ΔNp63-miR-141-3p-YAP1 regulatory axis in cervical cancer progression are dependent on histological subtype
Abstract Cervical cancer (CC) poses a significant global health challenge, necessitating the development of novel therapeutic strategies. The interplay between the p63 isoform (ΔNp63), micro...
Association between residential proximity to major roadways and nonfatal cardiovascular disease in Chinese older adults: a nationwide study
In-silico drug repositioning studies of Candida albicans Nitrogen permease reactivator 1 (Npr1) kinase
Cell-specific expression biases in human cortex of genes associated with neurodevelopmental disorders
Antimicrobial, antibiofilm and antioxidant activities of bioactive secondary metabolites of marine Scarus ghobban gut-associated Aspergillus niger: In-vitro and in-silico studies
Abstract Fungal extracts have garnered significant interest in recent years for their diverse applications in pharmaceutical field. This research focused on isolating fungi from the gut of S...