Scientific Reports

Golgi retention of KIT in gastrointestinal stromal tumour cells is phospholipase D activity-dependent

Abstract A constitutively active mutant of the receptor protein tyrosine kinase KIT is a major cause of gastrointestinal stromal tumours (GISTs). Recently, we di...

Effect of patterns of social activities on depressive symptoms among older adults in china: a latent class analysis of CHARLS

AI-derived CT biomarker score for robust COVID-19 mortality prediction across multiple waves and regions using machine learning

Coal-forming sedimentary model and its control on vertical reservoir heterogeneity of the upper carboniferous Benxi formation in Ordos basin, China

Saltations of cis-regulatory modules in Canidae and Hominidae

Abstract Dogs, which were segregated from wolves about thirty thousand years ago, show unique human-similar social-cognitive abilities. However, the genomic basis accounting for the phenotyp...

An intelligence technique for route distance minimization to store and marketize the crop using computational optimization algorithms

HDL cholesterol as a mediator of the relationship between breastfeeding and coronary atherosclerosis from a two-step Mendelian randomization analysis

Revolutionizing clinical decision making through deep learning and topic modeling for pathway optimization

Confinement of charge carriers in gapped bilayer graphene within magnetic and electrostatic barriers

Bioprospecting of six polyphenol-rich Mediterranean wild edible plants reveals antioxidant, antibiofilm and bactericidal properties against Methicillin resistant Staphylococcus aureus

Alzheimer’s disease risk prediction using machine learning for survival analysis with a comorbidity-based approach

Identifying ferroptosis-related genes in lung adenocarcinoma using random walk with restart in the PPI network

Optimizing equivalent testing for scaled projectile penetration into multilayer concrete targets with fuse overload via layer-by-layer chasing-catching methodology

Machine learning analysis of greenhouse gas sources impacting Africa’s food security nexus

Unraveling the luminescence secrets of turquoise nucleus cultivated pearls

Distinguishing the flow of airborne microorganisms along with environmental conditions and their influence on historic heritage buildings

Machine learning approaches for predicting the structural number of flexible pavements based on subgrade soil properties

Abstract This study presents a machine learning approach to predict the structural number of flexible pavements using subgrade soil properties and environmental conditions. Four algorithms w...

Traces of dipnoan fish document the earliest adaptations of vertebrates to move on land

A simulation approach to assessing vegetation configuration effects on thermal comfort in cold region pocket parks

Abstract Pocket parks, play a crucial role in enhancing residents’ thermal comfort and promoting ecological sustainability. Despite their significance, thermal comfort in cold-region spaces...

Experimental study on the mechanical properties and deformation failure characteristics of sandstone under graded equal amplitude cyclic loading and unloading

Computational screening of phytochemicals targeting mutant KRAS in colorectal cancer

The examination of in vitro photosensitizing efficacy of aloe-emodin loaded liposome following photodynamic therapy on melanoma cell lines

Eu isotope fractionation and hydrothermal alteration

Ensemble-based sesame disease detection and classification using deep convolutional neural networks (CNN)

Depression mediates the association between lipid accumulation products and overactive bladder