Scientific Reports

Scalable intracellular delivery via microfluidic vortex shedding enhances the function of chimeric antigen receptor T-cells

Brandon J. Sytsma, Vincent Allain, Struan Bourke et al. Feb 17, 2025 10.1038/s41598-025-89070-5

Abstract Adoptive chimeric antigen receptor T-cell (CAR-T) therapy is transformative and approved for hematologic malignancies. It is also being developed for th...

Multi-omics analysis identifies novels genes involved in glioma prognosis

Yingjie Li, Hong Sun Feb 17, 2025 10.1038/s41598-025-90658-0

A novel UPLC-based method to identify elephant and mammoth ivory

Chang Su, Yingshuang Xie, Bo Wang et al. Feb 17, 2025 10.1038/s41598-025-89678-7

Shallow burial of drip irrigation tape improves the water use efficiency of potatoes in semi-arid areas

Ting Guan, Peng Liu, Liguo Jia et al. Feb 16, 2025 10.1038/s41598-025-89295-4

Predicting visual field global and local parameters from OCT measurements using explainable machine learning

Md Mahmudul Hasan, Jack Phu, Henrietta Wang et al. Feb 16, 2025 10.1038/s41598-025-89557-1

Abstract Glaucoma is characterised by progressive vision loss due to retinal ganglion cell deterioration, leading to gradual visual field (VF) impairment. The standard VF test may be impract...

Fracture properties of dolomite and prediction of fracture toughness based on BP-ANN

Yu Guo, Dengkai Liu, Junying Rao et al. Feb 16, 2025 10.1038/s41598-025-89906-0

Unraveling the causal association between inflammatory bowel diseases and uveitis through mendelian randomization analysis

Min Zhong, Hongjin An, Huatian Gan Feb 16, 2025 10.1038/s41598-025-90462-w

Abstract To investigate the causal relationship between inflammatory bowel disease (IBD) and uveitis, we conducted a two-sample bidirectional Mendelian randomization (MR) analysis utilizing...

Machine learning-based identification of co-expressed genes in prostate cancer and CRPC and construction of prognostic models

Zhiheng Huang, Han Xu, Tianhe Zhang et al. Feb 16, 2025 10.1038/s41598-025-90444-y

Apolipoprotein E-ε4 allele is associated with perihematomal brain edema and poor outcomes in patients with intracerebral hemorrhage

Lei Huang, Qian Wu, Fei Ye et al. Feb 16, 2025 10.1038/s41598-025-89868-3

Cross-sectional study on the association between serum uric acid levels and non-alcoholic fatty liver disease in an elderly population

Jianqing Xu, Ming Deng, Yinghui Weng et al. Feb 16, 2025 10.1038/s41598-025-90590-3

Predicting preterm birth using machine learning methods

Anna Kloska, Alicja Harmoza, Sylwester M. Kloska et al. Feb 16, 2025 10.1038/s41598-025-89905-1

Identification of IGF2BPs-related mRNA signature for predicting the overall survival of lung adenocarcinoma

Xiang Xu, Weidi Zhao, Di Peng et al. Feb 16, 2025 10.1038/s41598-025-87874-z

Effect of Dzyaloshinskii Moriya interaction on magnetic tunnel junction based molecular spintronics devices (MTJMSD)

Babu Ram Sankhi, Christopher D’Angelo, Danielle Thompson et al. Feb 15, 2025 10.1038/s41598-025-88741-7

Impact of root distribution patterns on the elastic deformation resistance capacity and pore water development in root reinforced soil

Shumin Lyu, Jun Li, Xiaodong Ji et al. Feb 15, 2025 10.1038/s41598-025-88867-8

The effectiveness of a theory‑based health education program on self-efficacy and breastfeeding behaviors continuity of working mothers in Iran

Maryam Golnam, Laleh Hassani, Rakh-shaneh Goodarzi et al. Feb 15, 2025 10.1038/s41598-025-89943-9

Comprehensive analysis of the global, regional, and national burden of benign prostatic hyperplasia from 1990 to 2021

Xin Chen, Siyuan Yang, Zhangxin He et al. Feb 15, 2025 10.1038/s41598-025-90229-3

Exploring the microbiomes of camel ticks to infer vector competence: insights from tissue-level symbiont-pathogen relationships

Rua Khogali, Armanda Bastos, Dennis Getange et al. Feb 15, 2025 10.1038/s41598-024-81313-1

Distinct clinicopathological features and treatment differences in breast cancer patients of young age

Rasmus O. C. Humlevik, Amalie A. Svanøe, Turid Aas et al. Feb 15, 2025 10.1038/s41598-025-90053-9

Abstract The incidence of breast cancer in young women (aged under 40) is on the rise and is associated with more aggressive tumor characteristics and lower survival rates. Breast cancer is...

Integrated network pharmacology, molecular docking and experimental validation to investigate the mechanism of tannic acid in nasopharyngeal cancer

Meiwei Wang, Longmei He, Pan Yan Feb 15, 2025 10.1038/s41598-025-90211-z

The effectiveness evaluation of industry education integration model for applied universities under back propagation neural network

Ying Qi, Wei Feng Feb 15, 2025 10.1038/s41598-025-90030-2

Mutation of the gidB gene causes intrinsic streptomycin resistance in Bacillus velezensis

Hong-Eun Na, Sojeong Heo, Sumin Lee et al. Feb 15, 2025 10.1038/s41598-025-90258-y

Magnetic field detection with single mode spin wave interference in asymmetric structure

Yu Nishitani, Yukihiro Kaneko, Koji Sekiguchi Feb 15, 2025 10.1038/s41598-025-89367-5

The biodegradable polymer poly(butylene succinate-co-adipate) modulates the community structures of actively growing bacteria in rotifer culture water

Akito Taniguchi, Shuji Shirakashi, Tomoki Kawagishi et al. Feb 15, 2025 10.1038/s41598-025-90282-y

Effect of neoadjuvant chemotherapy on CD14 + CD16 + monocytes and soluble CD163 in Egyptian breast cancer patients

Sara Youssry, Hossam Ghoneim, Riham Barakat et al. Feb 15, 2025 10.1038/s41598-025-88719-5

Abstract Neoadjuvant chemotherapy (NACT) influences the anticancer response by favourably altering the immune microenvironment. However, the effects of NACT on peripheral monocytes and their...

Long non-coding RNA NEAT1 promotes colorectal cancer progression via interacting with SIRT1

Yuwei Li, Yunchun Xu, Xinya Yu et al. Feb 15, 2025 10.1038/s41598-025-90416-2

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