Scientific Reports

Early, very high-dose, and prolonged vitamin C administration in murine sepsis

Ok-Hyeon Kim, Tae Wan Kim, Hana Kang et al. May 20, 2025 10.1038/s41598-025-02622-7

Abstract This proof-of-concept study aimed to assess the optimal timing, dosing, and duration of vitamin C administration to increase survival and attenuate organ injuries in murine sepsis....

A novel luciferase-based assay for quantifying coronavirus-induced syncytia

Keisuke Oguma, Kenji Ogawa May 20, 2025 10.1038/s41598-025-02037-4

Abstract Coronaviruses can induce cell‒cell fusion that results in the formation of multinucleated syncytia through the interaction of viral spike proteins with host cell receptors. Quantify...

Canonical correlation analysis of anxiety symptom and behavioral inhibition/activation system among college students and their relationship with physical activity

Wenli Wang, Hairong Liu May 20, 2025 10.1038/s41598-025-01499-w

Balancing accuracy and cost in machine learning models for detecting medial vascular calcification in chronic kidney disease: a pilot study

Urszula Bialonczyk, Malgorzata Debowska, Lu Dai et al. May 20, 2025 10.1038/s41598-025-02457-2

Toxoplasma GRA16 attenuates Tau hyperphosphorylation and enhances autophagy in thrombin-treated HT-22 hippocampal neuronal cells

Seung-Hwan Seo, Do-Won Ham, Ji-Eun Lee et al. May 20, 2025 10.1038/s41598-025-00271-4

Generalists and keystone species drive rhizosphere microbial diversity and stability in feral Brassica napus

Yingshun Cui, Jihoon Kim, Mengqi Sun et al. May 20, 2025 10.1038/s41598-025-02562-2

The relationship between vertical malocclusions and ossification changes in the cranial base and upper cervical spine

Roberta Lekavičiūtė, Diana Šopagienė, Giedrė Trakinienė et al. May 20, 2025 10.1038/s41598-025-02547-1

Assessment of the participation of sulfhydryl proteins in the glutathione peroxidase mimicry of diphenyl diselenide in the presence of thiol alkylating agent

Ebenezer Morayo Ale, Ige Joseph Kade, Mgbede Joy Timothy et al. May 20, 2025 10.1038/s41598-024-77767-y

Entrainment of rhythmic tonal sequences on neural oscillations and the impact on subjective emotion

Jiaxin Ding, Xiaochen Zhang, Jingjing Liu et al. May 20, 2025 10.1038/s41598-025-98548-1

Brain structural differences between fibromyalgia patients and healthy control subjects: a source-based morphometric study

Elijah Agoalikum, Hongzhou Wu, Benjamin Klugah-Brown et al. May 20, 2025 10.1038/s41598-025-01070-7

Abstract Fibromyalgia (FM) is a chronic pain condition that predominantly affects women. Evidence implies that FM is associated with dysfunction of the central nervous system (CNS). In this...

Mathematical modelling of the role of Langerhans cells in the dynamics of HPV infection

Fahad Al Basir, Konstantin B. Blyuss, Aeshah A. Raezah et al. May 20, 2025 10.1038/s41598-025-02608-5

An accurate analytical model and application method for squirt flow in anisotropic fractured rocks

Yiwei Chen, Pingchuan Dong, Youheng Zhang May 20, 2025 10.1038/s41598-025-01439-8

Proteomic and transcriptomic analysis of the action mechanism of spermidine in mitigating the aging of Allium mongolicum seeds

Yan Men, Pengchao Wei, Xiumei Huang et al. May 20, 2025 10.1038/s41598-025-01372-w

Nationwide longitudinal study reveals impact of both national restriction levels and genetic risk factors on loneliness during the COVID-19 pandemic

Liam Quinn, Maria Didriksen, Christian Erikstrup et al. May 20, 2025 10.1038/s41598-025-02293-4

Conceptus signaling markers in immune cells enhance pregnancy prediction in beef cattle

Isabella Rio Feltrin, Gabriela Dalmaso Melo, Pedro Pisani Freitas et al. May 20, 2025 10.1038/s41598-025-01996-y

A method for detection of functional deficiencies due to unilateral vestibular impairment using the TUG test and IMU sensors

Marek Kamiński, Rafał Kotas, Wojciech Tylman et al. May 20, 2025 10.1038/s41598-025-02350-y

Optimization of multi-ancestry polygenic risk score disease prediction models

Jon Lerga-Jaso, Andrew Terpolovsky, Biljana Novković et al. May 20, 2025 10.1038/s41598-025-02903-1

Cognitive and non-cognitive factors predict pigs’ positions in an aggression social network

Lucy Oldham, Saif Agha, Gareth Arnott et al. May 20, 2025 10.1038/s41598-025-02023-w

Abstract Social network analysis (SNA) provides a means of understanding animals’ agonistic behaviour in a group. The aim of this study was to use SNA to characterise how individual cognitiv...

Study on calculation of nonlimit passive earth pressure of unsaturated soil behind retaining wall

Yaxin Zhang, Wenchao Gu, Qiliang Xu et al. May 20, 2025 10.1038/s41598-025-01565-3

Antimicrobial potential of Citrus australasica F. Muell. against methicillin-resistant Staphylococcus aureus supported by in silico analysis

Esraa M. Mohamed, Abeer H. Elmaidomy, Sara Mahmoud Farhan et al. May 20, 2025 10.1038/s41598-025-88113-1

Role of circulating MicroRNAs in prostate cancer diagnosis and risk stratification in the MCC Spain study

Inés Gómez-Acebo, Sara Valero-Dominguez, Javier Llorca et al. May 20, 2025 10.1038/s41598-025-01373-9

Neutrophil extracellular traps aggravate uremic cardiomyopathy by inducing myocardial fibroblast pyroptosis

Ying Xu, Yan Ren, Wenli Zou et al. May 20, 2025 10.1038/s41598-025-02383-3

Comparing Viet Nam’s national climate strategy’s effectiveness in mitigating infectious diseases against other OECD countries in South-East Asia

C. Dunsford, V. Q. Dat, J. Beardsley et al. May 20, 2025 10.1038/s41598-025-01975-3

Investigation of the dengue arbovirus in the cities of Bushehr Province through human blood sampling

Ebrahim Abbasi, Mohammad Djaefar Moemenbellah-Fard, Hamzeh Alipour et al. May 20, 2025 10.1038/s41598-025-02782-6

Prioritizing disability support systems by using Tamir’s complex fuzzy Dombi aggregation operators

Jabbar Ahmmad, Meraj Ali Khan, Ibrahim Al-Dayel et al. May 20, 2025 10.1038/s41598-025-00614-1

Articles in this Issue