Scientific Reports
Articles in this Issue
Stability indicating RP-HPLC method for estimation of finerenone and its related substances in new dosage form
Abstract Stability indicating RP-HPLC method was developed and validated for the estimation of finerenone (FIN) in pure and in new tablet dosage form. The proposed approach was applied and v...
Reducing impact load on RC-Slabs using Expanded Polystyrene (EPS)
Abstract Reinforced Concrete (RC) slabs are widely used in structural applications due to their ability to withstand heavy loads. However, under impact loading conditions such as falling obj...
A mobile robot bridging manual and automated bioscientific workflows by applying the Swiss army knife principle
Abstract The complexity and diversity of bioscientific research laboratories, creates significant challenges for automation. Their varying workflows, personnel, and instruments, often hinder...
Neural network-based image analysis of co-localized microorganisms and human cells on implant materials
Abstract Dental implant-associated infections increase the risk of implant failure, presenting significant challenges in modern dentistry. The host-microbe interaction plays a crucial role i...
Evaluating scar outcomes in pediatric burn patients following skin grafting
Abstract Scarring and its long-term sequelae, contribute significantly to morbidity following burn injuries. Factors associated with less favourable scar outcome...
Impact of adding carboplatin to docetaxel chemotherapy on testosterone levels and treatment outcomes in metastatic docetaxel-resistant prostate cancer
Abstract Docetaxel resistance, particularly post-androgen-receptor targeted therapy (ART), undermines its clinical utility in metastatic castration-resistant prostate cancer (mCRPC). This st...
Associations between cardiac adipose tissue and abdominal visceral fat and muscle based on computed tomography area and density
Abstract Computed Tomography (CT)-derived body composition parameters of cardiac adipose tissue (CAT), as well as abdominal adipose and muscle tissue are surrogates for the patient’s clinica...
Free-breathing cardiovascular magnetic resonance flow quantification can be an alternative to standard breath-holding approach
Abstract Cardiovascular magnetic resonance (CMR) evaluation of valvular heart disease is an important diagnostic tool when echocardiography is inconclusive. Phase contrast flow quantificatio...
Secondary neutron dose measurements at the DRACO laser-driven ion source
Abstract The pulsed nature of laser-driven ion sources and their relative large emission angles result in the production of secondary, undesired, pulsed neutron (and photon) radiation. Conve...
Facilitating laboratory automation using a robot with a simple and inexpensive camera detection system
Abstract Laboratory automation has transformed bioanalytical research, yet smaller research laboratories face challenges in adopting such technologies due to limited resources, time, and tec...
Astaxanthin attenuates DNA fragmentation and cognitive decline in type 2 diabetic rats
Abstract Potential properties of astaxanthin include immunomodulation, antioxidant, and anti-inflammatory effects. In diabetic rats, we examined the potential impacts and underlying mechanis...
Correlating pore space morphology with numerically computed soil gas diffusion for structured loam and sand, including stochastic 3D microstructure modeling
Abstract Biogeochemical soil processes are closely linked to the structure of soil. In particular, nutrient transport depends on diffusivity and permeability within the soil’s pore network....
Enhancing greenhouse cucumber production and quality utilizing organic residues as potting media through various cultivation modes and assessing application economics
Abstract Cocopeat is among the most frequently utilized substrates in soilless farming. Nonetheless, the extraction of Cocopeat generates a detrimental carbon fo...
Author Correction: Antinociceptive effect of intermittent fasting via the orexin pathway on formalin-induced acute pain in mice
Design and synthesis of novel pyridopyrimidine moieties linked to coumarin ring of potentially active cytotoxic agents and their docking study
Abstract Many pyridopyrimidine moieties linked to the coumarin ring were synthesized by the reaction of malononitrile with 7-hydroxy-4-methyl-2-oxo-2 H-chromene-8-carbaldehyde (2) directly i...
Ellipsoid zone reflectivity as a functional imaging biomarker for age-related macular degeneration: a MACUSTAR study report
Abstract This study evaluated the functional relevance of relative ellipsoid zone reflectivity (rEZR) on spectral-domain optical coherence tomography as a structural biomarker for retinal in...
Quadratic mixed convection of Maxwell-Buongiorno nanofluid over cubic stratified surface incorporating cross diffusion effects and solar radiation
Comparative field study of silver nanoparticles and garlic oil nanoemulsion for nematode control and yield enhancement in eggplant
Abstract The root knot nematodes Meloidogyne incognita are the most serious threats affecting eggplant, Solanum melongena L. Chemical nematicides are commonly used against plant-parasitic ne...
Immunohistochemical expression of smoothened in periocular basal cell, squamous cell and sebaceous carcinomas
Abstract Inhibition of Smoothened (SMO), a key protein in the Hedgehog signaling pathway, is effective for locally advanced basal cell carcinoma (BCC), but is not yet used for sebaceous carc...
Image statistics substantiate Gaudí’s naturalistic design principles
Abstract Human observers perceive natural and man-made environments differently, a distinction measurable through image statistics. However, limited evidence exists on how architectural styl...
Author Correction: CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells
Precision analysis of NGC 2158 with Gaia DR3
Abstract This research uses the third edition of the Gaia Data Release (DR3) to re-investigate the open star cluster NGC 2158. We employed the pyUPMASK Python package and HDBSCAN algorithms...
Nano Astaxanthin ameliorates myocardial infarction in rats through autophagy
Abstract Acute myocardial infarction (MI), a serious manifestation of ischemic heart disease, remains the culprit for mortality among coronary heart disease patients. Astaxanthin has demonst...
CCL20 expression is elevated in inflammatory bowel disease and attenuated by vitamin D metabolites
Abstract Intestinal epithelial overexpression of the Th17 cell chemoattractant CCL20 is implicated in inflammatory bowel disease and influenced by NOD2 mutations in Crohn’s disease. Vitamin...
Synthesis, characterization and theoretical studies of nitroxoline azo dye metal complexes and their role in mitigation of rheumatoid arthritis
Abstract In this work, an azo dye ligand of 2,6-dichloroaniline with nitroxoline (CPAQ), and its Zn(II), Cu(II), Cd(II), Ni(II) and Co(II) complexes have been synthesized. The structures of...