Scientific Reports

Nationwide comprehensive genomic profiling defines the genomic landscape of hepatocellular carcinoma across etiologies

Kengo Yasugi, Yoshiyasu Kono, Koichiro Tsutsumi et al. Dec 02, 2025 10.1038/s41598-025-30599-w

Identification and in silico evaluation of natural compounds from Annona muricata (soursop) leaves for colon cancer treatment

Md. Yeakub Ali, Afshana Jarin Asha, Farzana Akter Riti et al. Dec 02, 2025 10.1038/s41598-025-30151-w

Study on the rationality of the construction scheme for cement-stabilized macadam base course

Junqin Liu, Shibin Ma, Ze Li et al. Dec 02, 2025 10.1038/s41598-025-30424-4

The necessity of multimodal feedback for learning effective pedagogical policies with reinforcement learning

Lingxuan Che, Pu Guo, Haytham F. Isleem et al. Dec 02, 2025 10.1038/s41598-025-29892-5

Effect of diode laser power settings on calcium loss in acid-eroded dentin: an in-vitro analysis

Mohamed Fadul A. Elagib, Abeer Abdulhadi Alshehri, Rana Mohammed S. Alhajari et al. Dec 02, 2025 10.1038/s41598-025-30394-7

Mitigating distributed denial of service attacks using attribute subset selection with temporal convolutional networks

Hayam Alamro, Asmaa Mansour Alghamdi, Asma Alshuhail et al. Dec 02, 2025 10.1038/s41598-025-30137-8

Reduce the risk of microbial activity and cytotoxicity by Adansonia digitata pulp extract grown under the semi arid conditions of Sudan

Rasha Khalid Abbas Dec 02, 2025 10.1038/s41598-025-30536-x

Abstract Sudan is rich country for natural products like Adansonia digitata is locally name Gongolase and Tabldy, this pl...

The effect of trampoline training combined with CO-OP intervention on motor performance in children with developmental coordination disorder

Hong Zhang, Xiaofeng Zhu, Haitang Wang et al. Dec 02, 2025 10.1038/s41598-025-30801-z

Determining the effect of femoral anteversion and hip alignment parameters on lower limb and knee alignment post-total hip arthroplasty

Shunichi Yokota, Tomohiro Shimizu, Hotaka Ishizu et al. Dec 02, 2025 10.1038/s41598-025-30987-2

Abstract Total hip arthroplasty (THA) aims to restore hip joint alignment in patients with osteoarthritis (OA) or osteonecrosis of the femoral head (ONFH). While THA directly affects...

Cadaveric evidence on lymph node counts and grossing accuracy in pelvic lymph node dissection for prostate cancer staging

Pal Tunksakul, Parkpoom Piyaman, Varat Woranisarakul et al. Dec 02, 2025 10.1038/s41598-025-29196-8

Influence of ageing of graphene oxide on the properties and morphology of cement mortar

Suganthiny Ganesh, Charitha Thambiliyagodage, S. V. T. Janaka Perera et al. Dec 02, 2025 10.1038/s41598-025-30230-y

Knowledge, attitude and preventive practice of cutaneous leishmaniasis in Sodo district, Ethiopia

Lina Gazu, Zerish Zethu Nkosi, Nigatu Kebede Dec 02, 2025 10.1038/s41598-025-30623-z

Abstract Cutaneous Leishmaniasis (CL) is a neglected tropical disease endemic in Ethiopia, causing significant morbidity, disfigurement, and social stigma. Despite its public health...

pCPPs-sADNN: predicting cell-penetrating peptides using self-attention based deep neural network

Naif Almusallam, Shahid, Maqsood Hayat et al. Dec 02, 2025 10.1038/s41598-025-30754-3

Exploring drought adaptation strategies in pistachios through morpho-physiological analysis under deficit irrigation

Mozhgan Gholampoor, Mozhdeh Osku, Mohadeseh Jahanifard et al. Dec 02, 2025 10.1038/s41598-025-30740-9

O-GlcNAcylation of DDB1 at Ser-764 by OGT promotes cancer cell stemness in colorectal cancer through increased polyubiquitination of p53

Sora Jo, Ji Soo Kim, Seung Heon Baek et al. Dec 02, 2025 10.1038/s41598-025-30772-1

The impact of oral frailty and quality of life on gastrointestinal function in middle-aged and elderly patients: a cross-sectional study

Xia Li, Yaoqun Zhou, Shuying Hu et al. Dec 02, 2025 10.1038/s41598-025-30727-6

ICH-HPINet: a hybrid propagation interaction network for intelligent and interactive 3D intracerebral hemorrhage segmentation

Huimin Tao, Hui Jin, Cheng Yang et al. Dec 02, 2025 10.1038/s41598-025-30973-8

MAZ regulates fetal hemoglobin repression by activating MYB transcription

Dian Lu, Yinghong Yang, Bo Yang et al. Dec 02, 2025 10.1038/s41598-025-30733-8

Exploring shared microRNA profiles in liquid-based cytology and plasma as biomarkers of high-grade intraepithelial lesions

Stéphanie Calfa, Ana Julia Aguiar de Freitas, Rhafaela Lima Causin et al. Dec 02, 2025 10.1038/s41598-025-30514-3

Abstract High-grade cervical intraepithelial lesions (CIN 2/3) are critical targets for early detection in cervical cancer prevention. MicroRNAs are stable, tissue-specific molecules...

An explainable machine learning framework for multi-objective carbon reduction targeting material operational seasonal emissions in building retrofits

Huai Zhu, Chenghai Hu, Congyue Zhou et al. Dec 02, 2025 10.1038/s41598-025-29418-z

Black soldier fly larval oil as a renewable substrate for tailored PHA production

Shunmugham Keshaini, Idris Zainab-L, Kumar Sudesh Dec 02, 2025 10.1038/s41598-025-30033-1

Abstract Black soldier fly larvae (BSFL; Hermetia illucens ) are environmentally friendly source of protein and also cont...

Impacts of cognitive forcing and need for cognition on biased AI-assisted decision making about mental health emergencies

Shrika Vejandla, Aksharaa Ray, Laura Sikstrom et al. Dec 01, 2025 10.1038/s41598-025-30506-3

A cross sectional study of the relationship between clinical scores and timing of guidance for resident physicians in outpatient settings

Taiju Miyagami, Yuji Nishizaki, Taro Shimizu et al. Dec 01, 2025 10.1038/s41598-025-30748-1

A novel method for extraction of front boundary agents in multi-agent systems

Fengying Yang, Zia Ur Rehman, Ahmad Din et al. Dec 01, 2025 10.1038/s41598-025-29649-0

Holographic effect through full parallax multi-viewpoint augmented reality with extended depth of field

Jinho Yoon, Ki-hyuk Yoon, Wonshik Choi et al. Dec 01, 2025 10.1038/s41598-025-29734-4

Articles in this Issue