Scientific Reports
Articles in this Issue
Design, green synthesis, and bioevaluation of 1,3-thiazole-sulfonamide hybrids as antimicrobial and anti-inflammatory agent
Robustness of interstitial photodynamic therapy treatment planning under power and positional uncertainties in light delivery
Abstract While computer simulations can accurately model light dose delivery in interstitial photodynamic therapy (iPDT), predicting individual clinical outcomes...
Study on the mining stress field distribution law beneath isolated coal pillar in close coal seam and reasonable location of the roadway
Dynamic response characteristics, load-bearing efficiency in multimaterial tunnel assemblies subjected to recurrent intense fluid loading
HyMSS-GAD: a hybrid multi-stage framework for multi-view graph anomaly detection with structural, contextual, and geometric reasoning
Pharmacophore-driven kinase profiling applied to the PKIS2 chemogenomic dataset
Abstract We present a data-driven and unsupervised approach for extracting 3D pharmacophore hypotheses, without prior ligand selection, from a chemogenomic kinase dataset (406 kinase...
Nanoformulation of pomegranate peel extract enhances anti-psoriatic efficacy in a rat model
Abstract Psoriasis is a chronic inflammatory disease affecting 2% of the global population. Current treatments (e.g., corticosteroids and phototherapy) face limi...
Haptic feedback in violin education as a case study of robotic exoskeleton-mediated motor learning
Abstract This study explores the use of an upper-limb wearable exoskeleton for teaching violin technique to novices through haptic-assisted training. The educati...
Novel proteolytic post-translational modification in voltage-gated potassium channel KCNQ2
Abstract KCNQ2 is a member of the voltage-gated potassium (Kv) channel family and regulates neuronal activity through potassium ion efflux. Pathogenic variants o...
Advanced stacked modeling techniques for material porosity estimation via high-resolution computed tomography imaging
Cut instance mixing: A domain-specific data augmentation method applied to gastrointestinal lesion detection
Abstract Early detection of gastrointestinal lesions such as intestinal metaplasia (IM), dysplasia, and polyps remains challenging due to their subtle appearance and the scarcity of...
Mechanistic investigation of ammonium nitrogen adsorption on low-temperature pyrolysis cotton stalk biochar based on DFT calculations
Construction of automatic air monitoring point siting model based on convolutional neural network and K-means clustering
Analysis of the performance of a virtual gauge-based method in hydrological modeling of basins with no precipitation stations
Phytochemical responses of Dracocephalum kotschyi Boiss. to water deficit stress and different fertilizers
A qualitative study exploring critical care survivors’ and their clinicians’ shared experiences of navigating a fragmented care system
Abstract Recovery following a critical illness is challenging. Follow-up clinic provision is standard of care, but the effectiveness of services remain unclear, with some data demons...
Associations between early-life adversity, coping strategies, and adult mental health, brain, and cognition
Abstract Early adversity is associated with later mental health, brain, and cognitive outcomes, but the pathways are complex and may involve coping strategies an...
Analyzing the impact of gender-specific vaccination strategies and behavioral dynamics on HPV transmission
Investigation of the propagation behavior of hydraulic fractures and its influencing mechanisms in fractured reservoirs based on a hydromechanical coupling numerical model
RETRACTED ARTICLE: Flavokawain C suppresses nephroblastoma growth by inducing autophagy-mediated downregulation of FABP4 via AMPK/mTOR pathway
Mutation type, tyrosine kinase function in normal cell and tyrosine kinase inhibitor activity in cancers
Beyond decoration: free-standing lace embroidery for 3D shaped surgical mesh implants
Abstract Conventional mesh pockets manufactured from flat textiles by cutting and sewing often display wrinkles, excess material, and suboptimal fit on curved surfaces. This study de...
Reliability prediction of crane brakes based on the bayesian method
Thyme and cinnamon essential oils inhibit multidrug resistant Escherichia coli and Klebsiella pneumoniae and alter virulence transcripts
Abstract The increasing incidence of multidrug-resistant (MDR) Gram-negative pathogens, particularly Escherichia coli and...