Scientific Reports
Articles in this Issue
Retraction Note: Dysregulation of ghrelin in diabetes impairs the vascular reparative response to hindlimb ischemia in a mouse model; clinical relevance to peripheral artery disease
Non-ablative fractional laser 1940-nm treatment modulates epigenetic signatures associated with skin aging in a split-face investigation
Abstract Skin aging is driven by multiple factors, including cumulative environmental damage and epigenetic dysregulation, yet whether energy-based therapies can durably remodel the...
16 years of gelatinous zooplankton seasonal abundances reveal food availability and temperature as key drivers in Arctic latitudes
Abstract Year-round long-term monitoring programs are essential for assessing ecosystem functioning and change. In the Arctic, however, continuous multi-year sam...
Scutellaria baicalensis root-derived silver nanoparticles for enhanced Baicalin’s biological activities to inhibit breast cancer cells
Abstract Breast cancer (BC) remains a major global health challenge, particularly aggressive subtypes such as triple-negative breast cancer (TNBC), which often e...
Topological modeling of gene expression in the brain with Huntington’s disease reveals selective disruption of co-expression network
One-dimensional mid-IR defect-mode photonic crystal biosensor for oral cancer detection
Abstract A graphene-assisted one-dimensional photonic crystal biosensor for oral cancer detection in the mid-infrared region is theoretically proposed and analyz...
Effect of EPS geofoam inclusion parameters on the structural performance of rigid box culverts under induced trench installation
Abstract Buried rigid box culverts are widely used in transportation and water structures and are often constructed beneath high embankments. Due to the stiffness contrast between th...
The Use of Botulinum Toxin Type A in Esophageal Atresia Management: a Randomized, Controlled, Investigator-blinded Feasibility and Exploratory Trial in Piglets
Abstract Anastomotic strictures and leaks are severe complications following esophageal atresia (EA) repair. We hypothesized that esophageal injections of botuli...
Retraction Note: Graphene-based LSPR sensors enable polarization-independent detection of CEA antigens
Circulating tRF-Gly-GCC as a biomarker for colorectal cancer and Crohn’s disease activity
Abstract Distinguishing intestinal inflammation from colorectal cancer remains challenging using non-invasive biomarkers. tRNA-derived fragments have been implic...
Comparison of two analytical platforms for quantification of neuroglial biomarkers in blood samples: a single molecule array and an electrochemiluminescence assay
Abstract Advances in ultrasensitive immunoassays have enabled reliable quantification of neuroglial biomarkers in blood, providing valuable insights into neurolo...
Registration-based 3D Light Sheet Fluorescence Microscopy and 2D histology image fusion tool for pathological specimen
Abstract Histological analysis traditionally relies on thin tissue sections, providing inherently two-dimensional (2D) information. However, this approach captures only a fraction of...
Association of AQP5 gene variants and mRNA expression with caries severity in a dental practice cohort: a randomized trial
Abstract Aquaporin 5 (AQP5) is crucial for salivary secretion, composition and enamel mineralization. Genetic variations in AQP5 may influence susceptibility to...
Sustainable green concrete: multi-criteria optimization of bentonite–fly ash–silica fume ternary systems integrating life cycle assessment and mechanical performance analysis
Abstract Global CO₂ emissions from the cement sector account for approximately 8% of anthropogenic greenhouse gas emissions, underscoring the urgent need for sustainable concrete alt...
Plasma COL3A1 propeptide as a promising prognostic marker in oral squamous cell carcinoma
Abstract In this study, we aimed to evaluate the prognostic significance of collagens in patients with oral squamous cell carcinoma (OSCC). Plasma proteomics data from 40 OSCC patien...
Respiratory health impacts of coal-fired power plant emissions with transboundary environmental complexities
Abstract This interdisciplinary longitudinal study examines the association between PM 2.5 levels at sites downwind of a...
Zonal load transfer controlled by an L-shaped irregular coal pillar and the mechanism of rockburst induced by static-dynamic load superposition
Metaheuristic hyperparameter optimization of deep neural networks for demographic-aware autism spectrum disorder classification
Abstract Autism Spectrum Disorder (ASD) classification from neuroimaging data poses significant challenges due to high data heterogeneity and the complexity of learning robust repres...
Explainable artificial intelligence reveals divergent learning in pharmacophore-based hierarchical pooling graph neural networks
Abstract Hierarchical pooling is a promising mechanism to enhance graph neural networks (GNNs) by enabling multi-scale representation learning. Rationalization of hierarchical GNN pr...
Optimization of linear attenuation coefficients and characterization of mechanical and thermal properties in silica ash-reinforced PDMS composites
Abstract This investigation engineers multifunctional polydimethylsiloxane (PDMS) composites incorporating 0–50 wt% silica ash a valorized industrial byproduct a...
Hypervigilance and kinesiophobia characterize distinct exploratory data-driven profiles of temporomandibular disorders
Abstract Hypervigilance and kinesiophobia have been associated with temporomandibular disorders (TMD), but their relationship with specific diagnostic profiles r...
Correction: HS-RankFormer for efficient and robust RGB-to-Hyperspectral image reconstruction across domains
Two novel strains isolated from a brackish lake constitute Aeoliella fuhlenseeensis sp. nov. and Bythopirellula superficialaquae sp. nov. in the family Lacipirellulaceae
Abstract The strain collection of Heinz Schlesner (Kiel University, Germany) largely consists of budding bacteria collected from the 1980s to early 2000s. It sti...
Effect of Al₂O₃ nanoparticle reinforcement and annealing on PMMA composite performance for prosthetic feet
Dynamic multi-period optimal power flow considering renewable energy degradation and temperature derating
Abstract Renewable energy sources, such as solar and wind, play vital role in reducing emissions of carbon dioxide and combating climate change. However, their stochastic behavior ha...