Scientific Reports

Identification of compounds that repress DUX4 expression in facioscapulohumeral muscular dystrophy

Investigation of damage evolution in asphalt concrete under coupled ultraviolet aging and freeze-thaw cycles

Abstract To clarify the degradation law of crack resistance of asphalt concrete under the coupled action of UV aging and freeze–thaw cycles, semi-circular bending tests were conducte...

Area-adjusted influence of built-up pattern on urban land surface temperature in an arid landscape

6-gingerol attenuates renal interstitial fibrosis by downregulating PI3K/Akt/mTOR signaling pathway in unilateral ureteral obstruction rats

Characterization of gut microbiota in wild Asian elephants (Elephas maximus) from five forests across Thailand

Fecal and colonic microbiota differ in composition, function, diagnostic utility and correlation with inflammatory cytokines in ulcerative colitis

The failure mode and evolution process of geosynthetic reinforced embankments under rainfall

Anti-fibrotic effects of evogliptin in fibroblasts derived from post-burn hypertrophic scars

Advancing passenger next-station prediction via collaborative knowledge graph representational learning

Abstract Conventional passenger next station prediction models are often restricted by rigid graph structures, failing to account for the dynamic interactions between passengers and...

Efficient hydrogen generation from NaBH₄ methanolysis using a lithium-enhanced Dawson-type polyoxometalate catalyst

Impact of butanol-sunflower oil biodiesel–diesel blends on engine performance, combustion, and after-treatment emissions (DOC + SCR)

The effect of Staphylococcus aureus targeting ROS-dependent mitochondrial damage activating NLRP10 in inducing skin and soft tissue infection

A hybrid CNN–LSTM approach for large-scale Twitter sentiment analysis with explainable artificial intelligence

Impact of sky view factor on multimodal physiological responses: integrating EEG, heart rate, and thermal sensation in urban landscapes

Abstract Traditional thermal comfort models often fail to capture the dynamic neurophysiological complexity of outdoor human perception. This study introduces a...

Associations of the CHG index combined with obesity indicators with cardiovascular disease in early CKM syndrome using CHARLS data

The effects of an extemporaneous speech dual-task on center of pressure displacement and velocity in older adults

Development of novel reinforcement learning-based optimizer to impede tumor growth via radiochemotherapy

Abstract Current cancer treatment strategies prioritize algorithmic robustness and efficiency but frequently neglect critical aspects of patient safety and comfort. These approaches...

Density-aware and energy-gradient based relay selection for enhanced routing in mobile sink wireless sensor networks

The effect of astaxanthin supplementation on inflammatory markers, lipid profile, and anthropometric indices in patients with heart failure: a randomized controlled trial

Physics-guided cross-domain adaptation: a hierarchical hybrid transformer framework with contrastive learning for robust fault diagnosis under variable working conditions

Bioengineered zinc oxide nanoparticles derived from Teucrium polium as a multifunctional platform for anticancer activity, hemocompatibility, larval toxicity and photocatalytic remediation

Effect of organic material addition combined with tillage systems on organic carbon components and microbial communities in corn-fields of North East China

Biomechanical analysis of single leg deadlift under the effect of instability

Microfluidics-based engineered silver nanoparticles to control growth and biofilm formation in bacterial pathogens causing dental infection

Benchmarking machine learning approaches for polarization mapping in ferroelectrics using 4D-STEM

Abstract Four-dimensional scanning transmission electron microscopy (4D-STEM) provides rich, atomic-scale insights into materials structures. However, extracting specific physical pr...