Scientific Reports

Contribution of cytochrome P450-mediated metabolism to clavulanic acid-induced cytotoxicity in TK6-derived cytochrome P450-overexpressing cell lines

Jia-Long Fang, Xilin Li, Si Chen et al. Jul 15, 2026 10.1038/s41598-026-59728-9

Abstract Clavulanic acid, a β-lactamase inhibitor, is widely co-administered with amoxicillin (as in Augmentin ) to treat...

A green electrochemical sensor based on Fe/N-graphene hybrid nanostructure for trace-level determination of apremilast in biological and pharmaceutical samples

Marwah Naser, Wiem Bouali, Onur Karaman et al. Jul 15, 2026 10.1038/s41598-026-62081-6

Explainable deep learning for multi-country energy forecasting and sustainability analysis using climate and socio-economic indicators

Sajjad Ahmad, Turke Althobaiti, Muhammad Shoaib Saleem et al. Jul 15, 2026 10.1038/s41598-026-62451-0

Differential effects of ischemic preconditioning and cold compression on recovery in recreational crossfit athletes aged ≥ 40 years: a 2-week randomized controlled trial

Magdalena Hagner-Derengowska, Bartłomiej Kacprzak, Jakub Taradaj et al. Jul 15, 2026 10.1038/s41598-026-60885-0

Study on three-dimensional stress characteristics and torsional performance of titanium-steel tool joints

Feng Chen, Xiang Meng, Jiaqing Liu et al. Jul 15, 2026 10.1038/s41598-026-61305-z

Abstract Titanium alloy has promising applications in the ultra-deep well drilling field. When using titanium alloy drill pipes in composite drill strings, using titanium-steel tool...

Explainable machine learning for flood susceptibility mapping in Kyrgyzstan’s major urban areas

Nguyen Thi Thuy Linh, Chiranjit Singha, Vikas Kumar Rana et al. Jul 15, 2026 10.1038/s41598-026-58498-8

Surface and elemental analysis of stainless-steel needles after invasive physiotherapy: an exploratory scanning electron microscopy (SEM) study

Emilio J. Poveda-Pagán, Carlos Lozano-Quijada, José Vicente Toledo-Marhuenda et al. Jul 15, 2026 10.1038/s41598-026-57733-6

AI-assisted 6G-IoT system for environmental monitoring and risk management in mining sites

Khalid F. Alsirhani, Aymen Hlali, Anis Sahbani et al. Jul 15, 2026 10.1038/s41598-026-61649-6

MORF4L1, encoding a chromatin remodeler, is mutated in a recognizable dysmorphic neurodevelopmental disorder

Hanan E. Shamseldin, Dana Marafi, Mohammed AlMuhaizea et al. Jul 15, 2026 10.1038/s41598-026-61907-7

Predicting premature failure of quantum cascade lasers with different quantum designs using active machine learning

Ahmet Cagri Aydinkarahaliloglu, Arifin Nur Alif, Xiaojun Wang et al. Jul 15, 2026 10.1038/s41598-026-55243-z

Colonization of empty shells by cryptic fauna: a global event and important ecological innovation in Ordovician benthic ecosystems

Olev Vinn, Mark A. Wilson, Oive Tinn et al. Jul 15, 2026 10.1038/s41598-026-62638-5

Design of high-efficiency ultrathin perovskite solar cells using embedded plasmonic Au nanowires and SiO₂ antireflection nanoparticles

Hamideh Talebi, Rafat Rafiei Rad, Mitra Sarhangzadeh et al. Jul 15, 2026 10.1038/s41598-026-62295-8

Oregano oil, carvacrol, and thymol as novel ophthalmic antimicrobials: ocular safety, phenolic interactions, and antibacterial efficacy against clinically relevant ocular pathogens

Faith Uche Ukachukwu, Raid G. Alany, Myron Christodoulides et al. Jul 15, 2026 10.1038/s41598-026-62730-w

Abstract Bacterial ocular infections are a major cause of vision loss, with antimicrobial resistance limiting treatment efficacy. This study investigated oregano...

Tegoprazan-based dual therapy versus bismuth-containing quadruple therapy for Helicobacter pylori eradication: a prospective, multicenter, open-label, non-inferiority, randomized controlled trial

HaoCheng Wang, Yi Qu, Jun Wang et al. Jul 15, 2026 10.1038/s41598-026-62237-4

GIS-MCDA assessment of landfill suitability in flood-prone coastal Alappuzha, Kerala

Shinov Paitonpatrick, Sajad Nabi Dar Jul 15, 2026 10.1038/s41598-026-59081-x

Perceptions and care-seeking experiences of people living with type 2 diabetes in urban and rural settings in Central Uganda

Mathias Akugizibwe, Chaka Moreen Namulundu, Paul Kitandwe et al. Jul 15, 2026 10.1038/s41598-026-61382-0

Neopterin, tryptophan and kynurenine as biomarkers in glioblastoma

Petr Krupa, Lenka Kujovská Krčmová, Marketa Krupova et al. Jul 15, 2026 10.1038/s41598-026-52612-6

Fuzzy topological analysis of fuzzy Helm graphs with applications to protein interaction networks

Zeeshan Saleem Mufti, Ali H. Tedjani, Shama Liaqat et al. Jul 15, 2026 10.1038/s41598-026-61816-9

Abstract In biological and chemical networks, in which the strength of interactions is often not absolute, uncertainty is an inherent feature of many real-world...

An explainable hybrid deep learning framework for computational aesthetics, thematic mining, and sentiment analysis in english poetry

Ishfaq Yaseen, Mohamed S. A. Aly Jul 15, 2026 10.1038/s41598-026-61763-5

Mechanical and biological enhancement of glass ionomer cement through nanofiller integration: a preliminary study for improved restorative applications

Safa Al-Hammadi, Mengdi Li, Ahmed A. Madfa et al. Jul 15, 2026 10.1038/s41598-026-59123-4

Resilient federated intrusion detection with explainable AI: a robust CNN-LSTM architecture for extreme non-IID data distributions

Jallal-Eddine Moussaoui, Mehdi Kmiti, Yassine Maleh et al. Jul 15, 2026 10.1038/s41598-026-61994-6

Articles in this Issue