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Driver identification in advanced transportation systems using osprey and salp swarm optimized random forest model
Design and analysis of electromagnetic and mechanical structure of ultra-high-speed slotted solid rotor induction motor
Age- and sex-adjusted CT-based reference values for temporal muscle thickness, cross-sectional area and radiodensity
The associations of physical activity patterns and the triglyceride-glucose index in US adults: a secondary data analysis of NHANES (2007–2018)
Improving mechanical properties and electrical conductivity of Al-Cu-Mg matrix composites by GNPs and sc additions
Abstract To enhance the mechanical properties and electrical conductivity of Al-Cu-Mg-based composites, aluminum matrix composites containing scandium (Sc) and graphene nanoplatelets (GNPs) were fabricated by means of stepwise ball milling, vacuum hot pressing sintering, and hot rolling techniques. When Sc and GNPs were incorporated at concentrations of 0.1 wt% and 0.2 wt% respectively, the resultant composites demonstrated a maximum tensile strength of 326.81 MPa, an elongation of 3.2%, an electrical conductivity of 46.95% IACS, and a hardness of 112.96 HV. In comparison with the 2024 aluminum alloy matrix, enhancements of 39%, 255%, 51% and 51.21% were witnessed in tensile strength, elongation, electrical conductivity, and hardness respectively. These improvements can be primarily ascribed to the addition of Sc, which facilitated the precipitation of solute atoms and enhanced the interfacial bonding between the GNPs and the matrix, as well as the remarkable heterogeneous layered microstructure induced by the incorporation of GNPs. This study presents a feasible approach to concurrently enhance the strength and electrical conductivity of composites through the combined addition of Sc and GNPs.
Changes in microbiome composition during ontogeny and dispersal of the coral boring sponge Thoosa mismalolli
PET imaging of 52Mn labeled DOTATATE and DOTAJR11
Insights into the diverse roles of the terminal oxidases in Burkholderia cenocepacia H111
Abstract Burkholderia cenocepacia H111 is an obligate aerobic bacterium which has been isolated from a cystic fibrosis (CF) patient. In CF lungs the environment is considered micro-oxic or even oxygen-depleted due to bacterial activities and limited oxygen diffusion in the mucus layer. To adapt to low oxygen concentrations, bacteria possess multiple terminal oxidases. In this study, we identified six terminal oxidases of B. cenocepacia H111 and constructed reporter strains to monitor their expression in different environments. While the heme-copper oxidase aa 3 (cta) was constitutively expressed, the bd-1 oxidase (cyd) was induced under oxygen-limited growth conditions. The cyanide-insensitive bd-type terminal oxidase (cio-1) was mainly expressed in cells grown on the surface of solid medium or in liquid cultures in presence of cyanide, which is known to be produced in the CF lung by the often co-residing CF pathogen Pseudomonas aeruginosa. Indeed, a cio-1 insertional mutant was not able to grow in the presence of cyanide confirming the important role of Cio-1 in cyanide resistance. The caa 3 oxidase (caa), was only expressed under nutrient limitation when cells were grown on the surface of solid medium. We also investigated the involvement of two regulatory systems, Anr and RoxS/RoxR, in the expression of cio-1 and cyd. Our data suggest, that, given that Cio-1 is only present in prokaryotes and plays an important role in the defense against cyanide-producing P. aeruginosa, it may be a valuable drug target for treatment of polymicrobial infections in CF patients.
Abnormal alterations in structure-function coupling at the modular level in patients with postherpetic neuralgia
Oxytocin levels in response to CRH administration in hypopituitarism and hypothalamic damage: a randomized, crossover, placebo-controlled trial
TCTEX1D2 is essential for sperm flagellum formation in mice
Quantitative study on the environmental impact of Beijing’s urban rail transit based on carbon emission reduction
Abstract Urban rail transit, as an efficient and eco-friendly mode of transportation, plays a pivotal role in mitigating traffic congestion and lowering urban carbon emissions. Despite the significant contributions by scholars in this area, debates surrounding the quantification of carbon emissions during the operational phase of urban rail transit persist, particularly in assessing its impact on reducing ground traffic congestion. This study examines the passenger flow during Beijing’s morning and evening peak hours, assuming that all passengers initially using urban rail transit switch to buses and taxis during these periods. A traffic congestion prediction model is developed based on the analysis of actual traffic operation data under this assumption. Through this model, the study calculates the potential congestion times across various scenarios, employing a bottom-up approach to carbon emission estimation to analyze the impact on carbon emissions. Results spanning 2015 to 2021 suggest that substituting urban rail transit with buses could increase congestion by 37–92 min and 46–59 min during morning and evening peaks, respectively, leading to a 24-82% and 27-56% surge in carbon emissions. The conversion of all these vehicles to taxis would result in a direct paralysis of Beijing’s road transport network, with a corresponding increase in carbon emissions of between 289% and 556% and 333% and 614%, respectively.These outcomes emphasize the substantial efficacy of urban rail transit in curbing traffic congestion and carbon emissions.