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Potassium application enhances vegetative and reproductive yield of Zygopetalum maculatum and reduces post-flowering K depletion from storage organs of the orchid

Scientific Reports Siddhartha Sankar Biswas, Suman Natta, N. S. Kalaivanan et al. Mar 29, 2025 DOI: 10.1038/s41598-025-89452-9

Abstract The orchid cultivation is a significant sector in floriculture industry, and Zygopetalum maculatum is one of the most important orchid species of this industry due to its captivating fragrance and aesthetic appeal. Orchids, being epiphytic, are typically grown in soilless media, which lack essential macronutrients like nitrogen (N), phosphorus (P) and potassium (K), crucial for overall plant growth. Literature cited suggest several studies on combined effect of NPK on orchids, however, the studies on the impact of sole K application on morphological traits, and flower yield of Zygopetalum maculatum orchid have not been cited. Hence, this study was designed to explore the impact of K supplementation on morphological traits, floral yields, K uptake by the flowers, K dynamics in plant parts, and vase life of Zygopetalum maculatum flowers. The experiment was laid out in completely randomized design with six treatments of K application (i.e. T1 = No K in fertigation solution (K0), T2 = 10 mg K per L fertigation solution (K10), T3 = 25 mg K per L fertigation solution (K25), T4 = 50 mg K per L fertigation solution (K50), T5 = 75 mg K per L fertigation solution (K75) and T6 = 100 mg K per L fertigation solution (K100)), each treatment was replicated four times. The plants under the experimentation were treated with the nutrient solution weekly once. Results showed that K application enhanced water-extractable K content and dehydrogenase activity in the potting media. Morphological parameters such as bulb size, leaf number were significantly increased under the K100 treatment. Floral yields, including spike length, floret number per spike, floret dimension, and flower biomass, were also substantially higher with K supplementation. The K100 treatment produced 167% higher number of flower spike per plant with 44.4% higher number of significantly bigger sized florets per spike over K0 treatment. K content in leaves, bulbs, and roots significantly increased with K application. Flowering induced K reduction from back bulbs, leaves and roots. The post-flowering K reduction from different plant parts was minimized by K100 treatment. Partial regression analysis showed one unit K uptake by flowers caused, ~ 0.227, 0.564 and 0.317 unit K reduction from leaf, back bulb, and roots, respectively. Moreover, flowers from the K100 treatment exhibited an extended vase life compared to other treatments. Thus, it can be recommended that, 100 mg K L−1 fertigation solution should be applied weekly to sustainably improve Zygopetalum maculatum yields.

Risk factors and influence on neurodevelopmental outcomes of neonatal seizures in very low birth weight infants based on nationwide cohort

Scientific Reports Jin A Lee, Jin A Sohn, Sohee Oh Mar 29, 2025 DOI: 10.1038/s41598-025-86224-3

Motion of fullerene nanomachines on thermally activated curved gold substrates

Scientific Reports Saeed Seifi, Hossein Shaygani, Mohammad Ali Bakhtiari et al. Mar 29, 2025 DOI: 10.1038/s41598-025-95076-w

Chronic disturbance alters seed dispersal traits and frugivores resources in a dry tropical forest

Scientific Reports Carlos Iván Espinosa, Andrea Jara-Guerrero, Judith Castillo-Escobar et al. Mar 29, 2025 DOI: 10.1038/s41598-025-95319-w

Global burden of drowning and risk factors across 204 countries from 1990 to 2021

Scientific Reports Zhongyong Xie, Zhihua Huang, Qifeng Ran et al. Mar 29, 2025 DOI: 10.1038/s41598-025-95486-w

Flexible Patched Brain Transformer model for EEG decoding

Scientific Reports Timon Klein, Piotr Minakowski, Sebastian Sager Mar 29, 2025 DOI: 10.1038/s41598-025-86294-3

Abstract Decoding the human brain using non-invasive methods is a significant challenge. This study aims to enhance electroencephalography (EEG) decoding by developing of machine learning methods. Specifically, we propose the novel, attention-based Patched Brain Transformer model to achieve this goal. The model exhibits flexibility regarding the number of EEG channels and recording duration, enabling effective pre-training across diverse datasets. We investigate the effect of data augmentation methods and pre-training on the training process. To gain insights into the training behavior, we incorporate an inspection of the architecture. We compare our model with state-of-the-art models and demonstrate superior performance using only a fraction of the parameters. The results are achieved with supervised pre-training, coupled with time shifts as data augmentation for multi-participant classification on motor imagery datasets.

Gender moderates the mediating effect of psychological capital between physical activity and depressive symptoms among adolescents

Scientific Reports Xiangyu Luo, Hanqi Liu, Zhaoyang Sun et al. Mar 29, 2025 DOI: 10.1038/s41598-025-95186-5

Prevalence of pharmaceutical industry conspiracy theories among the polish population

Scientific Reports Marta Makowska, Akihiko Ozaki, Rafał Boguszewski Mar 29, 2025 DOI: 10.1038/s41598-025-95626-2

Establishment and characterization of a novel immortalized human aortic valve interstitial cell line

Scientific Reports Zihao Wang, Zhenqi Rao, Yixuan Wang et al. Mar 29, 2025 DOI: 10.1038/s41598-025-85909-z

Genetic targeting of myelinated primary afferent neurons using a new NefhCreERT2 knock-in mouse

Scientific Reports John CY. Chen, Lech Kaczmarczyk, Felipe Meira de-Faria et al. Mar 29, 2025 DOI: 10.1038/s41598-025-95874-2

Abstract Primary afferent neurons that convey somatosensory modalities comprise two large, heterogeneous populations: small-diameter neurons that give rise to slowly conducting unmyelinated axonal C fibers and medium-to-large diameter neurons with fast myelinated A fibers. Despite these two major groupings, tools to differentiate between unmyelinated and myelinated primary afferent fibers by genetic targeting have not been available; in particular, whereas numerous mouse driver lines exist to target different C fiber populations, genetic tools that target myelinated primary afferent populations are scarce. Here we describe a knock-in mouse line expressing tamoxifen-dependent CreERT2 under control of the Nefh gene, which encodes neurofilament heavy chain (NFH or NF200), a protein that is highly enriched in myelinated fibers. This mouse enables highly selective and efficient recombination of Cre-dependent reporters for functional and anatomical interrogation of myelinated fibers while excluding unmyelinated C fibers. In combination with other recombinase-expressing mouse lines, this genetic tool will be valuable for intersectional targeting of subpopulations of myelinated primary afferent fibers.

Development and evaluation of S-carboxymethyl-L-cystine-loaded solid lipid nanoparticles for Parkinson’s disease in murine and zebrafish models

Scientific Reports Shannon D Almeida, Sameera Hammigi Ramesh, Govardhan Katta Radhakrishna et al. Mar 29, 2025 DOI: 10.1038/s41598-025-95806-0

A novel wind speed prediction model based on neural networks, wavelet transformation, mutual information, and coot optimization algorithm

Scientific Reports Faezeh Amirteimoury, Farshid Keynia, Elaheh Amirteimoury et al. Mar 29, 2025 DOI: 10.1038/s41598-025-94082-2

Vorinostat attenuates UVB-induced skin senescence by modulating NF-κB and mTOR signaling pathways

Scientific Reports Qianlong Dai, Zhiwei Wang, Xue Wang et al. Mar 29, 2025 DOI: 10.1038/s41598-025-95624-4

A reference equation for peak oxygen uptake for cycle ergometry in Chinese adult participants

Scientific Reports Jinan Wang, Chuan Ren, Shunlin Xu et al. Mar 29, 2025 DOI: 10.1038/s41598-025-94207-7

PVA and PVP nanofibers combined with Helichrysum italicum oil preserve skin cell interactions, elasticity and proliferation

Scientific Reports Diletta Serra, Giuseppe Garroni, Sara Cruciani et al. Mar 29, 2025 DOI: 10.1038/s41598-025-95788-z

Determinants of care-seeking for ARI/Pneumonia-like symptoms among under-2 children in urban slums in and around Dhaka City, Bangladesh

Scientific Reports Samiun Nazrin Bente Kamal Tune, Gulam Muhammed Al Kibria, Mohammad Zahirul Islam et al. Mar 29, 2025 DOI: 10.1038/s41598-024-80979-x

Abstract Childhood pneumonia affects an estimated 18% of under-five children in Bangladesh. Urban slum-dwellers face challenges in healthcare-seeking. This study examined the factors influencing the healthcare-seeking for childhood pneumonia among under-two children in urban slums in Bangladesh. The study examined influence of children’s characteristics (age, sex, number of ARI/pneumonia symptoms, and duration of symptoms), maternal factors (age, education, and working status), and household characteristics (number of household members, wealth quintile, sex of household heads, age of household heads). The outcome variable was receiving care from a qualified medical provider for childhood pneumonia or pneumonia-like symptoms within 14 days before the collection of surveillance data. The research utilized data from the Urban Health and Demographic Surveillance System, which included 155,000 people from five slums in Dhaka and Gazipur City Corporation areas. Overall, 753 out of 4,679 (16%) children under two years of age were included in this study, all of whom had ARI/pneumonia-like symptoms. The mean age of these children was 11.4 months, and 50% were boys. Of them, 350 (46%) sought care from local pharmacies, while 37% sought care from medically trained providers. Logistic regression analyses indicated that children with multiple symptoms (AOR: 2.32, 95% CI: 1.71–3.14) and illness duration over seven days (AOR: 2.61, 95% CI: 1.51–4.51) had higher odds of receiving care from a medically trained provider. Higher maternal education compared to no formal education, having five or more household members compared to four or fewer, household heads aged 40–49 years compared to those under 25 years, a longer duration of living in the slum (more than 10 years compared to less than five years), and belonging to the richest wealth quintile compared to the poorest were protective factors for care-seeking from qualified providers. Further research is required to understand the context for designing appropriate interventions and comprehensive policies for improved child health regarding ARI/pneumonia-like symptoms.

Immunoinformatics method to design universal multi-epitope nanoparticle vaccine for TGEV S protein

Scientific Reports Shinian Li, Jingjing Yu, Chencheng Xiao et al. Mar 29, 2025 DOI: 10.1038/s41598-025-95602-w

Correlation between pierced earrings and the prevalence of metal allergies at Tokushima university hospital: a 15-year retrospective analysis

Scientific Reports Toyoko Tajima, Maki Hosoki, Mayu Miyagi et al. Mar 29, 2025 DOI: 10.1038/s41598-025-86868-1

Research on the desalination kinetics of carbon tableting electrodes for capacitive deionization water purification

Scientific Reports Yu Liang, Youheng Song, Yuchen Sun et al. Mar 29, 2025 DOI: 10.1038/s41598-025-95292-4

UV-Vis spectroscopy coupled with firefly algorithm-enhanced artificial neural networks for the determination of propranolol, rosuvastatin, and valsartan in ternary mixtures

Scientific Reports Ahmed Serag, Maram H. Abduljabbar, Yusuf S. Althobaiti et al. Mar 29, 2025 DOI: 10.1038/s41598-025-89187-7

Abstract In the present study, a simple, rapid and cost-effective analytical method was developed for the simultaneous determination of three commonly prescribed cardiovascular drugs: propranolol, rosuvastatin and valsartan. The method employed artificial neural networks (ANN) to model the relation between the UV absorption spectra of the drugs and their concentrations. An experimental design of 25 samples was employed as a calibration set, and a central composite design of 20 samples was used as a validation set. The firefly algorithm (FA) was evaluated as a variable selection procedure to optimize the developed ANN models resulting in simpler models with improved predictive performance as evident by lower relative root mean square error of prediction (RRMSEP) values compared to the full spectrum ANN models. Validation of the developed FA-ANN models demonstrated excellent accuracy, precision and selectivity for the quantification of the target analytes as per international conference on harmonisation (ICH) guidelines. Additionally, the greenness, analytical practicality and sustainability of the developed models were assessed using the analytical greenness (AGREE), blue applicability grade index (BAGI) and the red-green-blue (RGB) tools, confirming their environmentally friendly, practical and sustainable nature. This research shed the light on the potential of ANN coupled with UV fingerprinting for the rapid and simultaneous determination of critical cardiovascular drugs posing a significant impact on pharmaceutical quality control and patient monitoring.