Browse Articles

A group based network analysis for Alzheimer’s disease fMRI data

Online database of clinical algorithms with race and ethnicity

A novel avenue in the successful synthesis of Schiff base macromolecules via innovative plasma and classical approaches

Multi-omics study reveals differential expression and phosphorylation of autophagy-related proteins in autism spectrum disorder

Potassium application enhances vegetative and reproductive yield of Zygopetalum maculatum and reduces post-flowering K depletion from storage organs of the orchid

Abstract The orchid cultivation is a significant sector in floriculture industry, and Zygopetalum maculatum is one of the most important orchid species of this industry due to its captivating fragrance and aesthetic appeal. Orchids, being epiphytic, are typically grown in soilless media, which lack essential macronutrients like nitrogen (N), phosphorus (P) and potassium (K), crucial for overall plant growth. Literature cited suggest several studies on combined effect of NPK on orchids, however, the studies on the impact of sole K application on morphological traits, and flower yield of Zygopetalum maculatum orchid have not been cited. Hence, this study was designed to explore the impact of K supplementation on morphological traits, floral yields, K uptake by the flowers, K dynamics in plant parts, and vase life of Zygopetalum maculatum flowers. The experiment was laid out in completely randomized design with six treatments of K application (i.e. T1 = No K in fertigation solution (K0), T2 = 10 mg K per L fertigation solution (K10), T3 = 25 mg K per L fertigation solution (K25), T4 = 50 mg K per L fertigation solution (K50), T5 = 75 mg K per L fertigation solution (K75) and T6 = 100 mg K per L fertigation solution (K100)), each treatment was replicated four times. The plants under the experimentation were treated with the nutrient solution weekly once. Results showed that K application enhanced water-extractable K content and dehydrogenase activity in the potting media. Morphological parameters such as bulb size, leaf number were significantly increased under the K100 treatment. Floral yields, including spike length, floret number per spike, floret dimension, and flower biomass, were also substantially higher with K supplementation. The K100 treatment produced 167% higher number of flower spike per plant with 44.4% higher number of significantly bigger sized florets per spike over K0 treatment. K content in leaves, bulbs, and roots significantly increased with K application. Flowering induced K reduction from back bulbs, leaves and roots. The post-flowering K reduction from different plant parts was minimized by K100 treatment. Partial regression analysis showed one unit K uptake by flowers caused, ~ 0.227, 0.564 and 0.317 unit K reduction from leaf, back bulb, and roots, respectively. Moreover, flowers from the K100 treatment exhibited an extended vase life compared to other treatments. Thus, it can be recommended that, 100 mg K L−1 fertigation solution should be applied weekly to sustainably improve Zygopetalum maculatum yields.

Risk factors and influence on neurodevelopmental outcomes of neonatal seizures in very low birth weight infants based on nationwide cohort

Motion of fullerene nanomachines on thermally activated curved gold substrates

Chronic disturbance alters seed dispersal traits and frugivores resources in a dry tropical forest

Global burden of drowning and risk factors across 204 countries from 1990 to 2021

Flexible Patched Brain Transformer model for EEG decoding

Abstract Decoding the human brain using non-invasive methods is a significant challenge. This study aims to enhance electroencephalography (EEG) decoding by developing of machine learning methods. Specifically, we propose the novel, attention-based Patched Brain Transformer model to achieve this goal. The model exhibits flexibility regarding the number of EEG channels and recording duration, enabling effective pre-training across diverse datasets. We investigate the effect of data augmentation methods and pre-training on the training process. To gain insights into the training behavior, we incorporate an inspection of the architecture. We compare our model with state-of-the-art models and demonstrate superior performance using only a fraction of the parameters. The results are achieved with supervised pre-training, coupled with time shifts as data augmentation for multi-participant classification on motor imagery datasets.

Gender moderates the mediating effect of psychological capital between physical activity and depressive symptoms among adolescents

Prevalence of pharmaceutical industry conspiracy theories among the polish population

Establishment and characterization of a novel immortalized human aortic valve interstitial cell line

Genetic targeting of myelinated primary afferent neurons using a new NefhCreERT2 knock-in mouse

Abstract Primary afferent neurons that convey somatosensory modalities comprise two large, heterogeneous populations: small-diameter neurons that give rise to slowly conducting unmyelinated axonal C fibers and medium-to-large diameter neurons with fast myelinated A fibers. Despite these two major groupings, tools to differentiate between unmyelinated and myelinated primary afferent fibers by genetic targeting have not been available; in particular, whereas numerous mouse driver lines exist to target different C fiber populations, genetic tools that target myelinated primary afferent populations are scarce. Here we describe a knock-in mouse line expressing tamoxifen-dependent CreERT2 under control of the Nefh gene, which encodes neurofilament heavy chain (NFH or NF200), a protein that is highly enriched in myelinated fibers. This mouse enables highly selective and efficient recombination of Cre-dependent reporters for functional and anatomical interrogation of myelinated fibers while excluding unmyelinated C fibers. In combination with other recombinase-expressing mouse lines, this genetic tool will be valuable for intersectional targeting of subpopulations of myelinated primary afferent fibers.

Development and evaluation of S-carboxymethyl-L-cystine-loaded solid lipid nanoparticles for Parkinson’s disease in murine and zebrafish models

A novel wind speed prediction model based on neural networks, wavelet transformation, mutual information, and coot optimization algorithm

Vorinostat attenuates UVB-induced skin senescence by modulating NF-κB and mTOR signaling pathways

A reference equation for peak oxygen uptake for cycle ergometry in Chinese adult participants

PVA and PVP nanofibers combined with Helichrysum italicum oil preserve skin cell interactions, elasticity and proliferation

Determinants of care-seeking for ARI/Pneumonia-like symptoms among under-2 children in urban slums in and around Dhaka City, Bangladesh

Abstract Childhood pneumonia affects an estimated 18% of under-five children in Bangladesh. Urban slum-dwellers face challenges in healthcare-seeking. This study examined the factors influencing the healthcare-seeking for childhood pneumonia among under-two children in urban slums in Bangladesh. The study examined influence of children’s characteristics (age, sex, number of ARI/pneumonia symptoms, and duration of symptoms), maternal factors (age, education, and working status), and household characteristics (number of household members, wealth quintile, sex of household heads, age of household heads). The outcome variable was receiving care from a qualified medical provider for childhood pneumonia or pneumonia-like symptoms within 14 days before the collection of surveillance data. The research utilized data from the Urban Health and Demographic Surveillance System, which included 155,000 people from five slums in Dhaka and Gazipur City Corporation areas. Overall, 753 out of 4,679 (16%) children under two years of age were included in this study, all of whom had ARI/pneumonia-like symptoms. The mean age of these children was 11.4 months, and 50% were boys. Of them, 350 (46%) sought care from local pharmacies, while 37% sought care from medically trained providers. Logistic regression analyses indicated that children with multiple symptoms (AOR: 2.32, 95% CI: 1.71–3.14) and illness duration over seven days (AOR: 2.61, 95% CI: 1.51–4.51) had higher odds of receiving care from a medically trained provider. Higher maternal education compared to no formal education, having five or more household members compared to four or fewer, household heads aged 40–49 years compared to those under 25 years, a longer duration of living in the slum (more than 10 years compared to less than five years), and belonging to the richest wealth quintile compared to the poorest were protective factors for care-seeking from qualified providers. Further research is required to understand the context for designing appropriate interventions and comprehensive policies for improved child health regarding ARI/pneumonia-like symptoms.