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GPCR drug discovery: new agents, targets and indications

Nature Reviews Drug Discovery Javier Sánchez Lorente, Aleksandr V. Sokolov, Gavin Ferguson et al. Jun 01, 2025 DOI: 10.1038/s41573-025-01139-y

MYC in cancer: from undruggable target to clinical trials

Nature Reviews Drug Discovery Jonathan R. Whitfield, Laura Soucek Jun 01, 2025 DOI: 10.1038/s41573-025-01143-2

Live cell analysis of mobility and decay kinetics of the histone variant H3.3

Journal of Biological Chemistry Vishal Nehru, David Ball, Abhishek Mukherjee et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108557

The late-stage steps of Burkholderia cenocepacia protein O-linked glycan biosynthesis are conditionally essential

Journal of Biological Chemistry Leila Jebeli, Taylor A. McDaniels, Duncan T.T. Ho et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108515

The LDL receptor-related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions

Journal of Biological Chemistry Mashhood M. Wani, Joanna M. Cooper, Mary Migliorini et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110227

Prospective Observational Study of the Optinal Timing of Extubation in Cardiac Surgery Patients

Indian Journal of Critical Care Medicine Pandurang Tekawade, Vivek Vijay Tambe May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.53

Improving Clinical Decision-making for Hypercapnic Respiratory Failure and NIV: A Multi-facility Study

Indian Journal of Critical Care Medicine Dinesh Nirmal, Omini Kowkuntla, Nikhita Kalra May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.207

To Assess the Echocardiogram Parameters in Predicting the Outcome in Patients with Sepsis/Septic Shock

Indian Journal of Critical Care Medicine Magesh Parthiban, Ritika Swaminathan, Gopinathan T May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.121

Efficacy of Human Albumin in Prevention of Intradialytic Hypotension in Critically Ill Patients with Hypoalbuminemia Undergoing Haemodialysis – A Randomized Controlled Trial

Indian Journal of Critical Care Medicine Srikant Behera, Debananda Sahoo, Rakesh Kumar Mohapatra et al. May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.132

Comparison of Clinical Outcomes between Culture Positive and Culture Negative Sepsis and Septic Shock Patients

Indian Journal of Critical Care Medicine Yatin Mehta, Prabhat Kumar, Lalit Singh et al. May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.156

Therapeutic Plasma Exchange in Paediatric Intensive Care Unit: A Single Center Experience

Indian Journal of Critical Care Medicine Rakshay Shetty, Devika Chennakeshava, Milind Ballal May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.141

Correlation of Optic Nerve Sheath Diameter Measured Using Bedside Ultrasonography with Directly Measured Intracranial Pressure

Indian Journal of Critical Care Medicine Dilip Karnad, Ravindra Ghawat, Jasmine Nathani May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.187

Optimizing Fluid Management in Critical Care: Expert Consensus on the Clinical and Operational Impact of the Starling Fluid Management Monitoring System

Indian Journal of Critical Care Medicine Atul Jindal, Rajesh Pande, Indrani Hemantkumar et al. May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.198

Epidemiology and Clinical Profile of Critically Ill Obstetric Patients Requiring ICU Admission – An Observational Tertiary Care Center Study in North India

Indian Journal of Critical Care Medicine Rekha Sachan, Radhey Shyam Gangwar, Rashi Rastogi May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.219

Clinical and Microbiological Profile, and Outcomes of Melioidosis: A Multicentric Study from South India

Indian Journal of Critical Care Medicine Pavani Nimmala, Venkat Raman Kola, Monalisa Sahu et al. May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.218

10 mL/kg vs 20 mL/kg Fluid Bolus for Initial Resuscitation of Septic Shock in Children: A Randomized Clinical Trial

Indian Journal of Critical Care Medicine Arun Bansal, Jaspreet Kaur, Jayashree Muralidharan et al. May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.100

Prognostic Role of VExUS Score in Sepsis Patients – A Prospective Observational Study

Indian Journal of Critical Care Medicine Yatin Mehta, Chitra Mehta, Saurabh Nanda et al. May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.185

Role of Prophylactic Magnesium Supplementation in ICU Patients in Avoiding Other Dyselectrolytemias and their Complications

Indian Journal of Critical Care Medicine Shweta Ram Chandankhede, Srinivas GPVN, Savitha Appana May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.191

Effect of Therapeutic Bronchoscopy in Critically Ill Patients in Terms of Oxygenation and Respiratory Mechanics

Indian Journal of Critical Care Medicine Suraj Kumar, Praveen Das May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.220

Calcitonin Gene Related Peptide in Acute Exacerbation of COPD Patients Admitted to ICU

Indian Journal of Critical Care Medicine Mahesh PA, Sumalatha Arunachala, Mandya V Greeshma et al. May 31, 2025 DOI: 10.5005/jaypee-journals-10071-24933.3