Browse Articles
Discover research articles across all indexed journals
Analysis of the prognostic and immune role of MCM6 in pan-cancer and experimental validation in lung adenocarcinoma cells
Podocyte extracellular vesicles and immune mediators as urinary biomarkers in active lupus nephritis
FTIR based assessment of microplastic contamination in soil water and insect ecosystems reveals environmental and ecological risks
Synthesis and properties of carbon quantum dots as an antimicrobial agent and detection of ciprofloxacin
Daily insider threat detection with hybrid TCN transformer architecture
Development and interpretation of a machine learning risk prediction model for post-stroke depression in a Chinese population
Association between cardiometabolic index and self-reported symptoms of obstructive sleep apnea: a cross-sectional study
A randomized controlled trial of graded exercise rehabilitation enhances diaphragm function and exercise tolerance in patients with AECOPD
Shared and distinct patterns of cortical morphometric inverse divergence and their association with empathy in dancers and musicians
Abstract Neuroimaging research has demonstrated that long-term dance and music training can induce structural changes in the brain. However, most previous studies have focused on isolated structural metrics, neglecting the interregional similarities across cortical areas. In this study, we applied a novel morphometric measure, Morphometric Inverse Divergence (MIND), to assess cortical structural similarity in individuals with professional dance or music training. A total of 89 participants were incorporated in the study, including 25 dancers, 24 musicians, and 40 healthy controls (HC). Our findings showed that both dancers and musicians exhibited higher MIND values compared to HC, with musicians displaying significant differences particularly in the default mode network and somatomotor network. Furthermore, MIND values between the insula and superior parietal lobule, as well as between the superior frontal gyrus and cingulate gyrus, were positively correlated with the total IRI score and the Fantasy subscale. Both shared and distinct MIND patterns were identified between dancers and musicians. Musicians exhibited greater structural similarity in auditory cortical regions, whereas dancers showed increased similarity in visual and kinesthetic areas. Importantly, only the dancer group demonstrated a significant association between MIND values and empathic imagination. These findings provide new insights into how long-term artistic training influences cortical structure and social cognitive abilities.
Nanomechanical interlocking mechanism of 10-MDP nanolayering
Bioinformatics analysis of Rho-signal transduction genes in postmenopausal osteoporosis and periodontitis
Defected ground structure antenna array with metasurface inspired interlinked CSRR for 5G millimeter wave applications
Investigating the electronic structure and adsorption of OCN− and CN− on Si12C12 Fullerene-like cages using DFT and MD simulations
Heat shock proteins related signature characterizes immune status and predicts prognosis of gliomas
Depressive and anxiety symptoms mediate the relationship between family support and alcohol relapse in transplant recipients with alcohol-associated liver disease
Epidemiology of potential source, risk attribution of Clostridium perfringens from Egyptian broiler farms and genetic diversity of multidrug resistance strains
Abstract Clostridium perfringens induced necrotic enteritis (NE) became a persistent problem that had a major financial impact on the poultry business worldwide. Nevertheless, no prior research has assessed the related risk factors in Egyptian broiler farms. Thus, the purpose of this study is to perform an epidemiological analysis of C. perfringens occurrence, toxinotyping, and risk factors in El-Dakhlia and Damietta provinces, Egypt as well as their characteristics of antimicrobial resistance and molecular typing. From 25 broiler farms, 1100 samples were gathered. Antimicrobial resistance profiles and molecular typing were used to characterize the isolates. The findings revealed an overall prevalence of 26.3% (289/1100) from chickens’ clinical samples (30.3%; 273/900) and farm environmental samples (8%; 16/200). Toxinotyping of 289 isolates showed that 165 (57.1%) isolates were C. perfringens type A, harboring only alpha toxin gene (cpa) while 124 (42.9%) isolates were C. perfringens type G, containing netB gene. The cpb2 genes were found in 66 (22.8%) isolates with the highest positive rate from dead birds. Additionally, the study found a number of possible risk variables that were substantially linked to the prevalence of C. perfringens, including location in Damietta, winter season, history of coccidia infection, use of antimicrobial growth promoters, birds older than 22 days, wet litter type, and biosecurity strategy. Univariate and multivariate analyses showed a significant association between C. perfringens infection and grower chickens (OR 2.09, 95% CI 1.05–4.21, p = 0.037) compared to starter chickens. The isolates displayed their highest resistance rate to sulfamethoxazole-trimethoprim (94.5%), erythromycin, imipenem (94.1% each), penicillin, ampicillin, streptomycin, gentamycin (90.7% each), ampicillin/sulbactam (89.9%), cefuroxime and cefepime (85.8%), nalidixic acid (85.1%), and tetracycline (78.9%). Remarkably, none of the strains were resistant to meropenem. Multidrug-resistant was observed in 94.5% strains with MAR index of 0.32–0.79. The resistance genes carried by different strains were obviously different, among which the detection rate of aminoglycoside resistance gene aphA1, was the highest (100%), followed by bla TEM (85.8%), ermB, qnrS (85.1%), sul1 (80.6%), tetA(78.9%), drfA-1 (75.1%), qnrD, sul2 (60.2%), catA (57.4%), aadA (57.4%), ampC, mefA, qnrA (50.2%), bla CTX (46%), and tetM (42.2%). Enterobacterial repetitive intergenic consensus polymerase chain reaction (ERIC-PCR) was used to classify these isolates into eight different genotypes according to sampling place and sample type. The epidemiological information from this study was helpful in determining the danger of clostridial infection linked to Egyptian broiler farms. Our results also show that in order to combat multidrug resistance, new medications and antibiotic substitutes are required. The importance of conducting more surveys to better understand the prevalence of C. perfringens infection under strict management circumstances for various flock purposes cannot be overstated.
Linking carbon footprint methodologies and environmental protection via sustainable product development with a moderating role of regulatory compliance
Left to dry: unseen risks lurking on reusable medical devices
Disc deformation as a potential biomarker of nonspecific low back pain
Abstract Nonspecific low back pain (nLBP) lacks clear biomarkers, making diagnosis challenging. The disorder is commonly associated with annular fissures, which are hypothesized to trigger nerve endings to signal pain during disc deformation. Although symptoms worsen with load, MRI is typically performed in a relaxed state. Herein, a novel loading-based MRI method for non-invasive quantification of disc deformation was applied on 76 discs from 28 nLBP-patients to determine whether specific deformation patterns reflect fissures and pain using computer tomography and low-pressure discography during the same day as references. Discs without fissures and those with posterior fissures only displayed compression of annulus fibrosus posteriorly and expansion anteriorly, while discs with fissures both anteriorly and posteriorly and those with severe fissuring displayed elevated deformation and larger within-group variance (p = 0.001–0.04). Notably, discs with elevated anterior and low posterior deformation were more likely pain-signaling, whereas those with elevated posterior and low anterior deformation were often non-pain-signaling. At model probability thresholds below 0.38, all discs were correctly identified as non-painful and above 0.65, 86% were correctly identified as pain-signaling. Conclusively, this study provides in vivo evidence of a close interplay between disc deformation, fissures and pain, supporting the hypothesis that disc deformation contributes to nLBP.