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Discover research articles across all indexed journals

Australia’s world-first social media ban is a ‘natural experiment’ for scientists

Nature Rachel Fieldhouse, Mohana Basu Dec 11, 2025 DOI: 10.1038/d41586-025-04069-2

T. rex debate settled: contested fossils are smaller rival species, not juveniles

Nature Lawrence M. Witmer Dec 11, 2025 DOI: 10.1038/d41586-025-03552-0

Seminal fluid extracellular vesicles restore human sperm osmoregulation after cystic fibrosis transmembrane conductance regulator inhibition

Scientific Reports Sara C. Pereira, Oleksandra Fomichova, Isabel Damião et al. Dec 11, 2025 DOI: 10.1038/s41598-025-27409-8

Complex Regional Pain Syndrome

New England Journal of Medicine Andreas Goebel Dec 11, 2025 DOI: 10.1056/nejmcp2415752

VI-OCR: “Visually Impaired” optical character recognition pipeline for text accessibility assessment

Scientific Reports Qingying Gao, Roberto Manduchi, Pradeep Y. Ramulu et al. Dec 11, 2025 DOI: 10.1038/s41598-025-30982-7

Extended Treatment of Provoked Venous Thromboembolism

New England Journal of Medicine Dec 11, 2025 DOI: 10.1056/nejmc2515264

Bio-combustion synthesis of silver nanoparticles and evaluation of their effective antibacterial and photodegradation properties

Scientific Reports Sanjay S. Majani, K. B. Ramesh, Bharath K. Devendra et al. Dec 11, 2025 DOI: 10.1038/s41598-025-32173-w

Monteggia Fracture

New England Journal of Medicine Yen Cheng Chen, Ta-Li Hsu Dec 11, 2025 DOI: 10.1056/nejmicm2510553

A breathalyser-style test for detecting pancreatic cancer

Nature Esme Hedley Dec 11, 2025 DOI: 10.1038/d41586-025-03946-0

Application of CoFe2 − xMnxO4 spinel structures as an efficient electrode material for supercapacitors

Scientific Reports Seyyed Mohammad Hossein Jafari-Mousavi, Jafar Mostafaei, Mohammad Ahangari et al. Dec 11, 2025 DOI: 10.1038/s41598-025-32387-y

Raising a RUCkus

New England Journal of Medicine Dec 11, 2025 DOI: 10.1056/nejmp2514238

A novel migrasome-associated lncRNA model for clear cell renal cell carcinoma prognosis and immune response prediction

Scientific Reports Linlin Zhang, Longxin Dong, Tengzheng Tian et al. Dec 11, 2025 DOI: 10.1038/s41598-025-31455-7

Molecular Evidence of Multiorgan Damage in Patients with Immune-Related Adverse Events

New England Journal of Medicine Yuxuan Wang, Howard L. Li, Chetan Bettegowda et al. Dec 11, 2025 DOI: 10.1056/nejmc2513984

The influence of short-lived halogens on atmospheric chemistry and climate

Nature Alfonso Saiz-Lopez, Anoop S. Mahajan, Jonathan Abbatt et al. Dec 11, 2025 DOI: 10.1038/s41586-025-09753-x

Nanotyrannus and Tyrannosaurus coexisted at the close of the Cretaceous

Nature Lindsay E. Zanno, James G. Napoli Dec 11, 2025 DOI: 10.1038/s41586-025-09801-6

Differential associations of parents’ ADHD tendencies, boredom proneness, and parenting styles with children’s ADHD tendencies and boredom proneness

Scientific Reports Tianyi Zhang, Yuji Ikegaya, Izumi Uehara Dec 11, 2025 DOI: 10.1038/s41598-025-30163-6

Immeasurable Excellence — What Happens to Medicine without the “Good Doctor”?

New England Journal of Medicine Lisa Rosenbaum Dec 11, 2025 DOI: 10.1056/nejmms2510430

Overexpression of milk thistle SOD gene enhances drought tolerance in tobacco by improving photosynthesis and photoprotection

Scientific Reports Rahele Ghanbari Moheb Seraj, Masoud Tohidfar, Keyvan Esmaeilzadeh-Salestani et al. Dec 11, 2025 DOI: 10.1038/s41598-025-31510-3

Abstract Superoxide dismutase (SOD) is involved in the plant’s primary defense mechanism against the adverse effects of reactive oxygen species (ROS), maintaining ROS homeostasis within cells. Therefore, it is essential to investigate and compare the stress tolerance mechanism in both tolerant and sensitive plants. This study investigates the drought stress tolerance of Tobacco following transferring of a SOD gene obtained from a drought-tolerant plant. The SOD gene was isolated from the Milk thistle ( Silybum marianum L.) plant ( SmSOD ), cloned into the pBI121 (Binary Agrobacterium plasmid) expression vector, and subsequently transformed into Agrobacterium tumefaciens . Pre-cultivated Tobacco ( Nicotiana tabacum L.) plants were inoculated with the recombinant bacteria. Following validation of transgene integration via PCR, plants subjected to drought stress corresponding to ~ 50% field capacity for 5 days. Results demonstrated that the expression of SOD and its enzyme activity in drought-imposed transgenic plants were respectively 5 and 1.8 times higher than its expression and activity in wild-type plants. Imaging of chlorophyll fluorescence showed that drought-imposed transgenic plants had a higher maximum quantum yield of photosystem II (F v /F m ) and Non-photochemical quenching (NPQ) compared with wild-type plants. Stomatal density in drought-imposed plants was lower than in control plants, consistent across both transgenic and wild-type groups. Stomatal width decreased under stress in both plant types, with transgenic plants showing smaller width than wild-type plants. Stomatal length showed no significant differences between transgenic and wild-type plants or between drought-stressed and control conditions. In conclusion, SmSOD gene transfer from the Milk thistle to Tobacco plants increased the drought tolerance of the transgenic plants; this shed light on the path toward reaching drought-tolerant crops. These findings highlight the potential of SmSOD as a key gene for improving drought resistance in crops, offering promising applications in developing drought-tolerant crops for agriculture in water-scarce regions.

FDA’s New Plausible Mechanism Pathway

New England Journal of Medicine Vinay Prasad, Martin A. Makary Dec 11, 2025 DOI: 10.1056/nejmsb2512695

Will young universities set the pace in the age of AI?

Nature Bec Crew Dec 11, 2025 DOI: 10.1038/d41586-025-03949-x