Browse Articles

TNF-alpha: Roles in pathogenesis and therapeutics in cancer

Journal of Biological Chemistry Miriam Valenzuela Cardenas, Theodore Scott Nowicki Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111251

Emerging biologic modalities for targeted protein degradation

Journal of Biological Chemistry Alana G. Caldwell, Harshil Parmar, Xiaoyu Zhang Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111248

Divergent pathways of surfactant protein C maturation for disease-associated isoforms

Journal of Biological Chemistry Sarah Bui, Anamarie Reineberg, Dakota Jones et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111252

A tryptophan-phenylalanine binding motif for the histone methyltransferases MLL4 and MLL3

Journal of Biological Chemistry Soumi Biswas, Zohreh Tavaf, Caroline Benz et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111189

Organelles stick together through PDZD8-mediated condensate formation

Nature Reviews Molecular Cell Biology Lisa Heinke Mar 01, 2026 DOI: 10.1038/s41580-026-00950-8

P-bodies act as dynamic control hubs for RNA processing and storage

Journal of Biological Chemistry Matthew Wenjie Feng, Amir Mossanen-Parsi, Viktoras Stonys et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111273

The protease cathepsin K can debulk the cancer glycocalyx

Journal of Biological Chemistry Angel Kuo, Gabrielle S. Tender, William D. Chow et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111206

The terminal heme synthetic enzyme, coproheme decarboxylase, negatively regulates heme uptake in Mycobacterium tuberculosis

Journal of Biological Chemistry Rebecca K. Donegan, Yibo Fu, Jacqueline Copeland et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111197

The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation

Journal of Biological Chemistry Christina Michail, Jérémy Berthelet, Ariel E. Mechaly et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111259

Engineered nanobodies facilitate cryo-EM studies of small proteins

Nature Reviews Molecular Cell Biology Gangshun Yi, Dimitrios Mamalis Mar 01, 2026 DOI: 10.1038/s41580-025-00940-2

Acid ceramidase ASAH1 is a key regulator of epidermal ceramide levels and composition

Journal of Biological Chemistry Wakana Nobumoto, Tatsuro Naganuma, Nana Nozaka et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111178

RNA-binding protein tristetraprolin inhibits Th2 cell activation and differentiation in allergic rhinitis by promoting TRIM18 mRNA decay

Journal of Biological Chemistry Dongsheng Xing, Hongwei Cao, Yan Yang et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111240

SIRT7 safeguards ERα proteostasis via deacetylation-dependent degradation of unliganded and misfolded receptors

Journal of Biological Chemistry Mengdi Cao, Junfeng Zhang, Huixia Liu et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111173

Progress in stem cell-based embryo models and their applications in developmental biology and biomedicine

Nature Reviews Molecular Cell Biology Hao Wu, Hongmei Wang Mar 01, 2026 DOI: 10.1038/s41580-025-00942-0

Transcriptional plasticity of stromal cells amplifies their differentiation efficiency in vitro

Journal of Biological Chemistry Ali Jasim Mohammad Jamil, Mikkel Ørnfeldt Nørgård, Emilie Grupe et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111183

Antagonist nanobodies prevent protease inhibition by CD109

Journal of Biological Chemistry Kathrine Tejlgård Jensen, Ana Viana Almeida, Sanne Rönning et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111187

Unusual and atypical cyclooxygenase reactions

Journal of Biological Chemistry Claus Schneider, Alan R. Brash Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111247

Delineation of the active site of MtgB, a cobalamin-dependent glycine betaine methyltransferase

Journal of Biological Chemistry Jonathan Picking, Yunfeng Li, Tomislav Ticak et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111216

Mannose metabolic pathway senses glucose supply and regulates cell fate decisions

Journal of Biological Chemistry Ziwei Wang, Yasuhide Miyamoto, Takehiro Suzuki et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111213

KRAS4a and KRAS4b show distinct lipid-dependent regulation of RAS-RAF membrane dynamics

Journal of Biological Chemistry Konstantia Georgouli, Jeremy O.B. Tempkin, Liam G. Stanton et al. Mar 01, 2026 DOI: 10.1016/j.jbc.2026.111237