Browse Articles

Deep learning-based high-speed railway communication systems

Enantioselective Synthesis of 2-Oxabicyclo[2.1.1]hexanes and Bicyclo[2.1.1]hexanes via Catalytic Asymmetric Intramolecular Photocycloadditions

Evaluation of bacterial reduction by contemporary irrigation activation methods against Enterococcus faecalis biofilm in root canals

Configurational entropy and Adam-Gibbs relation for quantum liquids

Abstract As a liquid approaches the glass state, its dynamics slows down rapidly, by a few orders of magnitude in a very small temperature range. In the case of light elements and small molecules containing hydrogen (e.g., water), such a process can be affected by nuclear quantum effects (due to quantum fluctuations/atoms delocalization). In this work, we apply the potential energy landscape (PEL) formalism and path-integral computer simulations to study the low-temperature behavior of a Lennard-Jones binary mixture (LJBM) that obeys quantum mechanics. We show that, as for the case of classical liquids, (i) a configurational entropy S IS can be defined, and (ii) the Adam-Gibbs equation, which relates the diffusion coefficient of a liquid and its S IS , holds for the studied quantum LJBM. Overall, this study shows that one theoretical approach, the PEL formalism, can be used to describe low-temperature liquids close to their glass transition, independently of whether the system obeys classical or quantum mechanics.

Multi-scale covariance filtering for edge-preserving medical image fusion

Species- and variant-specific ACE2 compatibility shapes SARS-CoV-2 spillover potential in North American cervids

PtdIns(3,5)P2 is an endogenous ligand of STING in innate immune signalling

Improved modelling for vibrational energies of diatomic molecules using the generalized fractional derivative

Abstract By using the radial Schrödinger equation with the Morse potential in the context of the generalized fractional derivative (GFD), this work provides an important improvement in modelling the vibrational energy spectrum of diatomic molecules. We have used the generalized fractional Nikiforov-Uvarov (GFNU) method to derive an analytical solution for the energy eigenvalues in D -dimensional space by applying the Pekeris-type approximation to the centrifugal term. The proposed model is thoroughly examined across many electronic states, using a diverse set of twenty-two diatomic molecules, including astrophysically important species like SiO $$^+$$ and TaO, as well as CO, Na $$_2$$ , and AlH. The potential energy curves for the selected diatomic molecules have been produced using the Morse potential with the help of molecular constants. Furthermore, the pure vibrational energy levels for several diatomic molecules have been computed in both classical and fractional models. Our calculated vibrational energies are consistent with the Rydberg-Klein-Rees (RKR) data and previous studies. Additionally, it is seen that the vibrational energy spectra of different diatomic molecules calculated with fitted fractional parameters are improved compared to those obtained in the classical case for modelling the observed RKR data. The analysis of absolute percentage deviations at each level indicates that, for all examined diatomic molecules, the fractional derivative framework produces smaller and more consistent vibrational energy errors compared to the classical limit as the quantum number increases. Consequently, this study provides strong evidence that the GFNU method is a reliable and accurate technique to obtain the pure vibrational energies of various diatomic molecules.

Convection enhanced phase change composite fibers for advanced thermal management

An integrated, simulation-based framework linking satellite fire patterns and wireless sensor network planning in Tunisia

Gmppb-mutant mice exhibit dystroglycanopathy symptoms that are rescued with GSK3β inhibition or AAV-mediated GMPPB gene replacement

Efficient elimination of basic red 9 from wastewater using ceramic metal oxides containing carbon as novel nanohybrids

Assessing European cities with the 3-30-300 rule underscores the need for enhanced urban greening efforts

Abstract Urban green spaces are fundamental to sustainable city living, providing essential temperature regulation and social well-being. However, rapid urbanization often threatens these areas, exacerbating socio-economic disparities in access. This study evaluates adherence to the 3-30-300 rule - a guideline advocating for three trees visible from every home, 30% neighborhood canopy cover, and a park within 300 meters - across 862 European cities. Here we show that less than 15% of the studied population lives in full accordance with these criteria, while 21% reside in areas that do not meet any of the three benchmarks. Our analysis reveals strong vegetation inequalities, where higher levels of urban greenness are consistently associated with wealthier settlements. These findings indicate that most European cities currently fall short of providing equitable access to nature, underscoring an urgent need for a paradigm shift in urban planning to sustainably and equitably address the demands of growing populations.

Non-invasive continuous versus intermittent oscillometric arterial pressure monitoring and maternal hypotension during cesarean delivery: a randomized controlled trial

Author Correction: A porous tellurium interlayer for high-power and long-cycling garnet-based quasi-solid-state lithium-metal batteries

AC decoction augments chemotherapy in NSCLC by reshaping the tumor immune microenvironment: attenuating Tregs and enhancing CD8+ T cells

Tissue-adaptive bioelectronic fibers with temperature-induced self-tightening enable ultrastable neural interface

Chemical capture of diazo metabolites reveals biosynthetic hydrazone oxidation

Abstract Chemically reactive microbial natural products have enabled therapeutic development 1 via their well-established anticancer, antibiotic and antioxidant activities. However, discovery of reactive metabolites is particularly challenging because they may not tolerate traditional bioactivity-guided isolation workflows 2 . Diazo-containing natural products are a subset of highly reactive microbial metabolites that display potent bioactivity 3 and enable powerful biosynthetic transformations 4,5 ; however, instability of the diazo group to light 6 , heat 7 , mild acid 8 and mechanical shock 9 has precluded their efficient discovery and application. Here we develop a reactivity-based screening approach to capture diazo-containing metabolites and facilitate their discovery by mass spectrometry. This workflow revealed two novel diazo-containing natural products, 4-diazo-3-oxobutanoic acid ( 1 ) and diazoacetone ( 2 ), from the human lung pathogen Nocardia ninae . Biosynthetic investigations revealed a distinct enzymatic logic for diazo formation involving hydrazone oxidation catalysed by the metalloenzyme Dob3, and its biochemical characterization suggests promising future applications in biocatalysis. Overall, our work highlights the power of reactivity-guided strategies for identifying reactive metabolites and facilitating the discovery of unique enzymatic transformations.

Capillary-based optical fiber sensor for turbidity measurement

BRD4 directs myofiber identity and metabolic adaptation through CHD4 cooperation