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Genetic determinants of drug-induced gingival overgrowth
Stakeholder perspectives on the financial sustainability of community-based health insurance schemes in North Shewa Zone, Ethiopia: a qualitative study
Dynamic hypergraph network with multi modal fusion for cultural heritage tourism prediction
Predictive risk model for bone metastasis in intermediate-risk prostate cancer: a single-center retrospective analysis
Synthesis of fly ash-based zeolite and experimentation in catalytic converter for NOx reduction on diesel engines: a comparative study
Abstract This study presents the synthesis of low-cost ZSM-5 zeolite-like materials from hazardous coal fly ash and their application as metal-doped catalysts for nitrogen oxides (NO x ) reduction in diesel engine exhaust. The synthesized zeolite was prepared through acid treatment and hydrothermal crystallization, followed by metal doping with Cu, Fe, and Ce using an ion-exchange method. The catalysts were characterized using SEM, XRF, and XRD. Metal-doped zeolite formulations (Fe-ZSM-5, Cu-ZSM-5, Fe–Ce-ZSM-5, and Cu–Ce-ZSM-5,) were wash-coated onto cordierite monoliths and tested in a four-stroke CRDI diesel engine. The performance of the self-made catalytic converters (CCs) was compared with a commercial catalytic converter (CCC). Results showed that Fe–Ce-ZSM-5 and Cu–Ce-ZSM-5 achieved NO x reductions of 69% and 71%, respectively, at full load, which were approximately 7% higher than that of the commercial CC. All developed catalysts demonstrated significant reductions in hydrocarbons (HC) and carbon monoxide (CO) emissions, with only minimal influence on brake thermal efficiency (BTE). The findings demonstrate that fly-ash–derived ZSM-5 is a promising sustainable catalyst support for diesel exhaust after-treatment applications.
A parallel convolutional neural network with background removal and lesion segmentation for field plant disease severity classification
Glycaemic control during Ramadan in adults with type 1 diabetes using continuous glucose monitoring: Saudi Arabia
Integrative taxonomy of cryptic Pachypus chafers using museomics, morphometrics, barcoding, and genomic DNA analysis (Coleoptera: Scarabaeidae: Pachypodinae)
Abstract The taxonomy of the endemic Mediterranean genus Pachypus Dejean, 1821 has long been complicated by cryptic diversity and limited morphological differentiation. Based on extensive results from previous studies and new genomic data analyses, we perform here an integrative taxonomic revision of the genus. Using the morphological examination of the type material of most species and de novo sequencing of 978 metazoan-level universal single-copy orthologous genes (mzl-USCOs) of the almost 200-year-old lectotype of Pachypus impressus Erichson, 1840, we proposed refined species hypotheses within the genus. Resulting species entities from a recent study using mzl-USCOs were aligned within the framework of existing nomenclatorially available names inferred from Museomics and comparative morphological analyses. We additionally removed two existing taxon names from synonymy with Pachypus candidae and raised them to valid species: Pachypus cornutus (Olivier, 1789) and P. impressus Erichson, 1840. Pachypus excavatus Fabricius, 1792 is confirmed here as a valid species. This study also revealed one new synonymy: Pachypus impressus Erichson, 1840 (= P. melonii Sparacio, 2008, syn. n.). Furthermore, we described seven new species which had been already delineated in our earlier study: Pachypus baroniensis sp. n., P. franginii sp. n., P. gallurensis sp. n., P. matzaccara sp. n., P. occidentalis sp. n., P. pelegrinus sp. n., and P. sulcis sp. n. Extensive morphometric analyses of five datasets (one based on distance measurements and four on body outlines), including about 1,900 specimens, confirmed the cryptic character of most Pachypus species, as morphospace plots of all traits largely overlapped among most of the species. This made the assignment of analyzed type specimens to retrieved morphometric clusters a poor predictor of the true identity of mzl-USCO-defined species. We designated a lectotype of Pachypus impressus Erichson, 1840 and a neotype of Pachypus cornutus (Olivier, 1789). Finally, for the purpose of enhancing applied DNA-based studies and metabarcoding, we extracted the 5’ COI DNA sequences from the raw DNA reads of our target enrichment nucleotide data as well as from the newly sequenced lectotype of P. impressus . The phylogenetic tree inferred from these data was compared with that obtained from the previously produced 3’ COI data generated by Sanger sequencing. The habitus and male genitalia of all species are illustrated, an identification key is provided, and the distribution of the species is shown. As a result of our long-term studies of the genus, we also provide new insights into the ecology and distribution of the group, which may be relevant to conservation across the entire circum-Tyrrhenian region. Zoobank link: urn:lsid:zoobank.org:pub:34F3F1E1-2A40-4450-95B3-0336E6E2CF52.
Predicting the range expansion of larger benthic foraminifera under earth’s changing climate
Analytical investigation of natural frequencies and mode shapes of a multi-span beam with a disc and spring supports
Prevalence and severity of sleep-disordered breathing in individuals with Down syndrome using a portable home-based diagnostic device: a pilot study
Subparticle Operando Imaging for Probing Electrocatalytic Intermediates and Cation Effects
Tunable electronic and optical properties of Ru₂S₂X (X = Si, Ge, Sn, Pb) monolayers
Spontaneous and Efficient Oxime Synthesis by Al-Catalyst Assembly
Expressive activation enhances user satisfaction in AIGC co-creation through perceived control and meaning-making
Insights into small-molecule neurotransmitter levels and distribution during tissue regeneration in an ear pinna model in mice
Abstract Best known for their functions in the nervous system, neurotransmitters also play prominent roles in wound healing. The study analysed the spatiotemporal expression of acetylcholine, dopamine, gamma-aminobutyric acid, serotonin, and its metabolite, 5-hydroxyindoleacetic acid, in regenerating mouse ear pinna during normal healing and during enhanced regeneration induced by the epigenetic inhibitor zebularine and retinoic acid, using HPLC-MS/MS. In terms of time, acetylcholine, dopamine, and gamma-aminobutyric acid showed a gradual decrease during the acute phase on days 3 and 7 post-injury, while serotonin, after a sharp decline on day 3, increased markedly. Zebularine and retinoic acid reduced gamma-aminobutyric acid, acetylcholine, and serotonin in the acute phase. On day 42, over 4 weeks after drug administration and 3 weeks after wound closure, the epigenetic treatment resulted in an elevation in serotonin and a decline in acetylcholine. In spatial terms, the neurotransmitter responses showed similar trends in the wound vicinity and distal tissues, except for a significant increase in serotonin in the wound area and gamma-aminobutyric acid in distal tissues on days 7 and 3, respectively. Decoding the concerted tissue profiles of small-molecule neurotransmitters helps reveal their roles in wound healing and informs the design of regenerative therapies targeting neurotransmitter pathways.