YL1004 is a SARS-CoV-2 papain-like protease inhibitor with immunomodulatory and antiviral activity in mice

J Jinshan Nan H Huiping Shuai J Jingxin Qiao R Rui Zeng (School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Key Lab of Electrical Insulation & Thermal Aging) L Lianzhao Du Y Yan Chen C Chaemin Yoon J Jiaheng Hu W Wenyu Guo L Lei Wang C Chong Huang L Lengjing Zhu Y Yueshan Li S Shanshan Zhang X Xinyue Deng (Department of Chemistry, Institute of Molecular Aggregation Science, School of Science) J Jingxuan Sun L Le Du R Ronggang Ma (West China School of Public Health and West China Fourth Hospital, and State Key Laboratory of Biotherapy) Q Qiao Huang J Jian Lei (Department of Public Foundation) H Hin Chu (Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong) S Shengyong Yang