Widespread gene-environment interactions shape the immune response to SARS-CoV-2 infection in hospitalized COVID-19 patients

Haley E. Randolph; Raul Aguirre-Gamboa; Elsa Brunet-Ratnasingham; Tomoko Nakanishi; Zepeng Mu; Veronica Locher; Ellen Ketter; Cary Brandolino; Catherine Larochelle; Alexandre Prat; Nathalie Arbour; Anne Dumaine; Andrés Finzi; Madeleine Durand; J. Brent Richards; Daniel E. Kaufmann; Luis B. Barreiro

doi:10.1038/s41467-026-72393-w

Widespread gene-environment interactions shape the immune response to SARS-CoV-2 infection in hospitalized COVID-19 patients

H Haley E. Randolph R Raul Aguirre-Gamboa E Elsa Brunet-Ratnasingham T Tomoko Nakanishi Z Zepeng Mu V Veronica Locher E Ellen Ketter C Cary Brandolino C Catherine Larochelle (Neuroimmunology Research Laboratory, Multiple Sclerosis Clinic, University of Montreal Hospital Research Center) A Alexandre Prat N Nathalie Arbour A Anne Dumaine A Andrés Finzi M Madeleine Durand J J. Brent Richards D Daniel E. Kaufmann L Luis B. Barreiro

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published April 28, 2026

DOI 10.1038/s41467-026-72393-w

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (17)

H

Haley E. Randolph

R

Raul Aguirre-Gamboa

E

Elsa Brunet-Ratnasingham

T

Tomoko Nakanishi

Z

Zepeng Mu

V

Veronica Locher

E

Ellen Ketter

C

Cary Brandolino

C

Catherine Larochelle

Neuroimmunology Research Laboratory, Multiple Sclerosis Clinic, University of Montreal Hospital Research Center

A

Alexandre Prat

N

Nathalie Arbour

A

Anne Dumaine

A

Andrés Finzi

M

Madeleine Durand

J

J. Brent Richards

D

Daniel E. Kaufmann

L

Luis B. Barreiro

Widespread gene-environment interactions shape the immune response to SARS-CoV-2 infection in hospitalized COVID-19 patients

Article Details

Journal Info

Authors (17)

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