Vitamin D3 ameliorates R-loop-induced replication stress and chromosomal instability in MED12-mutant uterine fibroids

Sribalasubashini Muralimanoharan; Ana Corachán; Azad Khosh; Sierra Hathaway; Natalia Garcia; Susivarshini Karthigayan; Claire Schenken; Nicholas Stansbury; Robert Schenken; Maria Victoria Bariani; Qiwei Yang; Eloise Dray; Mazhar Adli; Hortensia Ferrero; Ayman Al-Hendy; Thomas G. Boyer

doi:10.1038/s41598-026-60844-9

Vitamin D3 ameliorates R-loop-induced replication stress and chromosomal instability in MED12-mutant uterine fibroids

S Sribalasubashini Muralimanoharan A Ana Corachán A Azad Khosh S Sierra Hathaway N Natalia Garcia S Susivarshini Karthigayan C Claire Schenken N Nicholas Stansbury R Robert Schenken M Maria Victoria Bariani Q Qiwei Yang (Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering) E Eloise Dray M Mazhar Adli H Hortensia Ferrero A Ayman Al-Hendy T Thomas G. Boyer

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Article Details

Journal Scientific Reports

Volume / Issue Vol. 1, Issue 1

Published July 06, 2026

DOI 10.1038/s41598-026-60844-9

ISSN 2045-2322

Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (16)

S

Sribalasubashini Muralimanoharan

A

Ana Corachán

A

Azad Khosh

S

Sierra Hathaway

N

Natalia Garcia

S

Susivarshini Karthigayan

C

Claire Schenken

N

Nicholas Stansbury

R

Robert Schenken

M

Maria Victoria Bariani

Q

Qiwei Yang

Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering

E

Eloise Dray

M

Mazhar Adli

H

Hortensia Ferrero

A

Ayman Al-Hendy

T

Thomas G. Boyer

Vitamin D3 ameliorates R-loop-induced replication stress and chromosomal instability in MED12-mutant uterine fibroids

Article Details

Journal Info

Authors (16)

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