Versatile 2-Oxoglutarate-Dependent Dioxygenases Catalyze Radical-Mediated Multifunctional Skeleton Reconstructions and Oxidation Modifications of Taxoids

X Xue Tang X Xuan Zhang L Li-Ping Long (State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy) S Si Wu X Xin-Yu Fan (State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy) J Jia Liu X Xian-Jing Zhang (State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy) C Chen Lin (School of Pharmaceutical Sciences) F Fei-Yan Gou (State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy) Y Yuan-Hui Yu (State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy) K Kai Guo (State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy) J Jing Chen C Chun-Lin Tan (State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy) Y Yun Wang Y Yu Zheng P Peng Zhang J Jonathan Gershenzon (Department of Biochemistry) R Rui-Bo Wu (School of Pharmaceutical Sciences) S Sheng-Hong Li (State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy) Y Yan Liu

Article Details

Volume / Issue Vol. 148, Issue 10
Published March 18, 2026
Pages 11333-11343
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (20)

X

Xue Tang

X

Xuan Zhang

L

Li-Ping Long

State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy

S

Si Wu

X

Xin-Yu Fan

State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy

J

Jia Liu

X

Xian-Jing Zhang

State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy

C

Chen Lin

School of Pharmaceutical Sciences

F

Fei-Yan Gou

State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy

Y

Yuan-Hui Yu

State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy

K

Kai Guo

State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy

J

Jing Chen

C

Chun-Lin Tan

State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy

Y

Yun Wang

Y

Yu Zheng

P

Peng Zhang

J

Jonathan Gershenzon

Department of Biochemistry

R

Rui-Bo Wu

School of Pharmaceutical Sciences

S

Sheng-Hong Li

State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy

Y

Yan Liu