β-Thalassemia minor is associated with high rates of worsening anemia in pregnancy

Arielle L. Langer; Brynn B. Goggins; Erica B. Esrick; Geoffrey Fell; Nancy Berliner; Katherine E. Economy

doi:10.1182/blood.2024026736

β-Thalassemia minor is associated with high rates of worsening anemia in pregnancy

A Arielle L. Langer (Brigham and Women’s Hospital, Boston) B Brynn B. Goggins (2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA) E Erica B. Esrick (3Division of Hematology/Oncology, Boston Children’s Hospital, Boston, MA) G Geoffrey Fell (5Department of Data Science, Dana-Farber Cancer Institute, Boston, MA) N Nancy Berliner (1Department of Hematology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA) K Katherine E. Economy

Abstract

Abstract We identified 347 pregnancies in patients with β-thalassemia minor. Hemoglobin was &lt;9 g/dL in 31% during third trimester and 7.6% at delivery. Postpartum hemorrhage occurred in 8.9%. Forty-six percent of IV iron administration was to iron-replete patients.

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Article Details

Journal Blood

Volume / Issue Vol. 145, Issue 6

Published February 06, 2025

Pages 648-651

DOI 10.1182/blood.2024026736

ISSN 0006-4971

Publisher Elsevier BV

Journal Info

Blood

Elsevier BV

ISSN: 0006-4971 Health Sciences

Authors (6)

A

Arielle L. Langer

Brigham and Women’s Hospital, Boston

B

Brynn B. Goggins

2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA

E

Erica B. Esrick

3Division of Hematology/Oncology, Boston Children’s Hospital, Boston, MA

G

Geoffrey Fell

5Department of Data Science, Dana-Farber Cancer Institute, Boston, MA

N

Nancy Berliner

1Department of Hematology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

K

Katherine E. Economy

β-Thalassemia minor is associated with high rates of worsening anemia in pregnancy

Abstract

Article Details

Journal Info

Authors (6)

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