Update and new advances in fertility preservation and cancer

G Gwendolyn P. Quinn (Department of Obstetrics and Gynecology Grossman School of Medicine New York University New York New York USA) M Michelle Bayefsky (Icahn School of Medicine at Mount Sinai New York New York USA) B Brooke Cherven (Aflac Cancer and Blood Disorders Center at Children’s Healthcare of Atlanta Emory University School of Medicine Atlanta Georgia USA) L Lauren V. Ghazal (School of Nursing University of Rochester Rochester New York USA) K Kara N. Goldman (Division of Reproductive Endocrinology and Infertility Department of Obstetrics and Gynecology Northwestern University Feinberg School of Medicine Chicago Illinois USA) N Nina Francis Levin (Division of Metabolism, Endocrinology, and Diabetes University of Michigan Medical School Ann Arbor Michigan USA) L Leena Nahata (Department of Pediatrics The Ohio State University College of Medicine Columbus Ohio USA) B Bobby Najari (Department of Urology Grossman School of Medicine New York University New York New York USA) S Sameer Thakker (Department of Urology Grossman School of Medicine New York University New York New York USA) D Daniel R. Greenberg (Department of Urology Northwestern University Feinberg School of Medicine Chicago Illinois USA) J Joshua A. Halpern (Department of Urology Northwestern University Feinberg School of Medicine Chicago Illinois USA) S Susan T. Vadaparampil (Department of Health Outcomes and Behavior Moffitt Cancer Center Tampa Florida USA)

Abstract

Abstract Adolescents and young adults with a cancer diagnosis face unique challenges during treatment and into survivorship related to fertility and family building. This review provides an updated overview of the impact of cancer and its associated treatments, including novel treatments in male and female fertility. An overview of fertility preservation and family building options, including experimental options, is also provided.

Article Details

Volume / Issue Vol. 75, Issue 6
Published December 01, 2025
Pages 602-629
ISSN 0007-9235
Publisher Wiley

Journal Info

CA: A Cancer Journal for Clinicians

Wiley

ISSN: 0007-9235 Open Access Q1 Medicine

Authors (12)

G

Gwendolyn P. Quinn

Department of Obstetrics and Gynecology Grossman School of Medicine New York University New York New York USA

M

Michelle Bayefsky

Icahn School of Medicine at Mount Sinai New York New York USA

B

Brooke Cherven

Aflac Cancer and Blood Disorders Center at Children’s Healthcare of Atlanta Emory University School of Medicine Atlanta Georgia USA

L

Lauren V. Ghazal

School of Nursing University of Rochester Rochester New York USA

K

Kara N. Goldman

Division of Reproductive Endocrinology and Infertility Department of Obstetrics and Gynecology Northwestern University Feinberg School of Medicine Chicago Illinois USA

N

Nina Francis Levin

Division of Metabolism, Endocrinology, and Diabetes University of Michigan Medical School Ann Arbor Michigan USA

L

Leena Nahata

Department of Pediatrics The Ohio State University College of Medicine Columbus Ohio USA

B

Bobby Najari

Department of Urology Grossman School of Medicine New York University New York New York USA

S

Sameer Thakker

Department of Urology Grossman School of Medicine New York University New York New York USA

D

Daniel R. Greenberg

Department of Urology Northwestern University Feinberg School of Medicine Chicago Illinois USA

J

Joshua A. Halpern

Department of Urology Northwestern University Feinberg School of Medicine Chicago Illinois USA

S

Susan T. Vadaparampil

Department of Health Outcomes and Behavior Moffitt Cancer Center Tampa Florida USA